建筑能效设计简便方法

本文介绍了一种用于建筑设计初始阶段，还不能获取详细设计资料时的建筑能效设计简便方法。该方法通过对建筑窗墙维护结构，建筑方位，照明及设备的合理设计达到建筑节能的目的。该方法编制成计算机软件，使用灵活，方便，可供建筑师进行建筑设计时对各建筑设计方案的供热，空调，通风，照明能耗及CO2排放值进行比较，进而优化建筑设计方案。该方法适合于新建或改建的非住宅建筑。中国各地区的气候资料可以集成于此软件中，供建筑师用于中国的建筑设计。     

The psychology of Lightner Witmer.

Discusses the work of Lightner Witmer (1867–1956), whose recognition of the need to treat "mentally and morally retarded" children led him to establish the first psychological clinic in the US at the University of Pennsylvania in 1896. The following topics are addressed: background and biographical information, Witmer's 4 areas of practical work (statistical and clinical investigation; establishment of a clinic and school; practical opportunities for those in teaching, medicine, and social work; and training of psychological experts), services offered by the clinic (diagnosis, assessment, and treatment), and Witmer's theories regarding the nature of psychology. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A PREDICTIVE MODEL FOR THE THROUGHPUT OF UNBALANCED, UNBUFFERED THREE-STATION SERIAL LINES

The three-station serial line is a fundamental building block of many complex production systems. In this paper we develop methods for predicting the throughput of unbalanced three-station serial lines. We model the variability of processing times using a variety of probability distributions that spans the range of variabilities encountered in practice. We develop procedures for approximating throughput, for any allocation of total mean processing time, based on the throughput of a small number of easily analyzed cases.     

Mechanisms of cyclin-dependent kinase inactivation by progestins

The steroid hormone progesterone regulates proliferation and differentiation in the mammary gland and uterus by cell cycle phase-specific actions. In breast cancer cells the predominant effect of synthetic progestins is long-term growth inhibition and arrest in G1 phase. Progestin-mediated growth arrest of T-47D breast cancer cells was preceded by inhibition of cyclin D1-Cdk4, cyclin D3-Cdk4, and cyclin E-Cdk2 kinase activities in vitro and reduced phosphorylation of pRB and p107. This was accompanied by decreases in the expression of cyclins D1, D3, and E, decreased abundance of cyclin D1- and cyclin D3-Cdk4 complexes, increased association of the cyclin-dependent kinase (CDK) inhibitor p27 with the remaining Cdk4 complexes, and changes in the molecular masses and compositions of cyclin E complexes. In control cells cyclin E eluted from Superdex 200 as two peaks of approximately 120 and approximately 200 kDa, with the 120-kDa peak displaying greater cyclin E-associated kinase activity. Following progestin treatment, almost all of the cyclin E was in the 200-kDa, low-activity form, which was associated with the CDK inhibitors p21 and p27; this change preceded the inhibition of cell cycle progression. These data suggest preferential formation of this higher-molecular-weight, CDK inhibitor-bound form and a reduced number of cyclin E-Cdk2 complexes as mechanisms for the decreased cyclin E-associated kinase activity following progestin treatment. Ectopic expression of cyclin D1 in progestin-inhibited cells led to the reappearance of the 120-kDa active form of cyclin E-Cdk2 preceding the resumption of cell cycle progression. Thus, decreased cyclin expression and consequent increased CDK inhibitor association are likely to mediate the decreases in CDK activity accompanying progestin-mediated growth inhibition.     

Today's Access Technologies

The drive to deliver an increasingly diverse range of telecommunications products over an access network, designed originally for the delivery of telephony, has demanded, in recent years, the development and deployment of a range of copper, fibre and radio-based delivery solutions. This paper outlines the history and the current status of some of the key access delivery solutions that exist within BT's portfolio of access components today.     

Neuropsychological testing and functional outcome for individuals with traumatic brain injury

The relationship between performance on neuropsychological measures and the vocational and independent living functioning of individuals with traumatic brain injury was examined. The Wechsler Adult Intelligence Scale-Revised (WAIS-R) IQ and Stroop Color and Word Test scores differentiated individuals who required no assistance with activities of daily living from those requiring some level of assistance. Only the Stroop Color and Word Test scores differentiated individuals who were competitively employed or engaged in degree-oriented education from those who were unemployed or in sheltered or supported employment. Wechsler Memory Scale-Revised (WMS-R) scores did not differentiate these groups.