Erweiterung des Vierscheitelsatzes der Differentialgeometrie mit Anwendung in der Theorie der Koppelkurven der ebenen Getriebe

Zusammenfassung Die Erweiterung des Vierscheitelsatzes ergibt die M?glichkeit auch Aussagen zu treffen über die Scheitelpunkte der ebenen geschlossenen Kurvengattungen mit Singularit?ten wie Doppelpunkten und auch teilweise geradlinig verlaufenden geschlossenen Kurven. Eine Anwendung finden die Ergebnisse in den Koppelkurven der ebenen Getriebe. Schlie?lich wird eine analytische Methode zur Ermittlung der Scheitelpunkte einer bekannten ebenen Kurve angegeben.     

Sonderlagen der Getriebe und ihre Anwendungen

Zusammenfassung Durch Anwenden von Sonderlagen, die sich für alle Getriebeketten gleicher Art in universeller Weise erfassen lassen, gelingt es, die Bestimmung der Winkelgeschwindigkeiten und der Winkelbeschleunigungen der Getriebeglieder sowie der Gelenkkr?fte in allgemein gültiger Form festzulegen. Das Verfahren wurde zun?chst auf viergliedrige Kurbelschwingen angewendet und soll sp?ter auf Getriebe mit mehr als vier Gliedern ausgedehnt werden.     

Immunoblotting detection of autoantibodies to human epidermis filaggrin: a new diagnostic test for rheumatoid arthritis

OBJECTIVE: We previously reported that so-called antikeratin antibodies (AKA) and antiperinuclear factor (APF) recognize epitope(s) present on human epidermal filaggrin. In the present study, we developed a new diagnostic test for rheumatoid arthritis (RA) based on detection of antifilaggrin autoantibodies (AFA) by immunoblotting. METHODS: We tested 670 serum samples, including 190 RA. AFA titers were estimated by immunoblotting on filaggrin enriched human epidermis extracts, and AKA titers by indirect immunofluorescence (IIF) on rat esophagus epithelium. Diagnostic values of the tests were compared. RESULTS: Each test resulted in diagnosis of more than 40% of RA samples, with a specificity of 0.99. Although the tests were strongly correlated, their association allowed the diagnosis of more than 60% of RA samples, with the same specificity. CONCLUSION: Immunoblot detection of AFA, a simple and standardizable test, may be an alternative or complement to conventional IIF detection of AKA.     

Laser cutting of 7050 Al alloy reinforced with Al2O3 and B4C composites

In the present study, laser cutting of 7050 aluminum alloy sheets reinforced with Al₂O₃ and B₄C particles are carried out. The cut geometry is examined using scanning electron microscope and the optical microscope. The lump parameter analysis technique is used to formulate and determine the kerf width size. The predictions for kerf width are compared with experimental data. The percentage kerf width size variation along the cut edges is determined and the influence of the laser power level and duty cycle of the laser pulses on the percentage kerf width size variation is examined. It is found that 7050 aluminum alloy reinforced with 20% Al₂O₃ composite results in relatively large kerf width size as compared to its counter parts that corresponding to 7050 aluminum alloy reinforced with 20% B₄C composite. The kerf width size predicted agreed with the experimental data for both composites.     

A Bi-Enzymatic Cascade Pathway towards Optically Pure FAHFAs**

Recently discovered endogenous mammalian lipids, fatty acid esters of hydroxy fatty acids (FAHFAs), have been proved to have anti-inflammatory and anti-diabetic effects. Due to their extremely low abundancies in vivo, forging a feasible scenario for FAHFA synthesis is critical for their use in uncovering biological mechanisms or in clinical trials. Here, we showcase a fully enzymatic approach, a novel in vitro bi-enzymatic cascade system, enabling an effective conversion of nature-abundant fatty acids into FAHFAs. Two hydratases from Lactobacillus acidophilus were used for converting unsaturated fatty acids to various enantiomeric hydroxy fatty acids, followed by esterification with another fatty acid catalyzed by Candida antarctica lipase A (CALA). Various FAHFAs were synthesized in a semi-preparative scale using this bi-enzymatic approach in a one-pot two-step operation mode. In all, we demonstrate that the hydratase-CALA system offers a promising route for the synthesis of optically pure structure-diverse FAHFAs.     

Why self‐cleaning is important for solar thermal receivers?

Surface cleaning remains essential for the sustainable operation of high performance solar thermal receivers. Cleaning of optical surfaces, such as solar troughs and absorbers, requires energy intensive efforts because of the large surface area involvement such as those observed in solar farms. In addition, self‐cleaning of such surfaces becomes demanding because of lowering the cleaning costs, reducing the waste of resources, such as clean water, and minimizing the complication of the mechanical systems incorporated. Self‐cleaning of surfaces is associated with the low adhesion between the surface and the foreign particles; in which case, these particles can be removed easily from the surfaces in a cost‐effective way. The surface energy and contact area of the surface are two main important parameters influencing the particle adhesion on the surfaces. In this case, reducing the surface energy and forming micro/nano size pillars on the surface through texturing lower the particle adhesion on the surfaces significantly. In solar thermal energy harvesting applications, metallic or composite materials are used and texturing the surface remains challenging in terms of cost and precision of operation when conventional texturing methods are used. One of the methods to create surface texture consisting of micro/nano pillars is to use the laser beam ablation. This results in hierarchical distribution of surface texture with desired pillar heights1. In addition, laser surface texturing offers significant advantages over the conventional techniques. Some of these advantages include fast processing, precision of operation, and low cost. Although the laser processing involves with high temperature processing and thermally induced stresses remain important, the defects sites can be minimized via controlling the process parameters during the texturing. Introducing the assisting gas on the texturing surface enables to generate compounds such as oxide or nitride species, which lower the surface energy considerably. Consequently, investigation of laser texturing of solar energy materials while incorporating the assisting gas becomes essential. In the present perspective, the laser surface texturing of solar energy materials for thermal power applications is presented together with challenges and future perspectives. Specifically, the followings will be presented: (1) the texture characteristics of laser treated metallic and ceramic surfaces; (2) wetting state of the textured surface, and optical properties of textured surface in terms of absorption of the solar irradiation.     

Evaluation of alginate and zein films as a carrier of natamycin to increase the shelf life of kashar cheese

The aim of this study was to develop alginate and zein films containing natamycin, a natural antifungal agent, in order to limit/prevent the mould growth on the surface of kashar cheeses. The films were prepared by casting, and characterized in terms of antimicrobial and mechanical properties (tensile strength, elongation-at-break, and elastic modulus), and their morphology was examined by scanning electron microscopy (SEM). Mechanical properties of the zein films were found to be weaker than the alginate films. SEM analysis indicated that alginate films have a more regular structure than zein films, and a more homogenous distribution was observed at lower concentrations of natamycin. The antifungal activities of both films increased as the natamycin concentration (100, 200, 500, 1000, 2000, and 4000 ppm) increased; however, alginate films exhibited relatively high antifungal activity. The effects of films on the shelf life of kashar cheeses inoculated with Aspergillus niger and Penicillium camemberti were investigated during their storage under refrigerator conditions for 45 days. At high-natamycin concentrations, zein films showed higher antifungal activity against both fungi at the end of the storage period.