A critical review on physical factors and functional characteristics that may explain a sex/gender difference in work-related neck/shoulder disorders

The objective of this paper is to critically review recent literature on physical and functional sex/gender (s/g) differences, with focus on physical determinants associated with neck/shoulder musculoskeletal injuries. It is well known that there are s/g differences in anthropometrical and functional body characteristics (e.g. size and strength). However, s/g differences may be wrongly attributed if data analysis does not include appropriate corrections (e.g. by strength for endurance). Recent literature on motor control shows that there may indeed be s/g differences in muscle coordination and movement strategies during upper limb tasks that are not currently explained by methodological inadequacies. Moreover, recent studies have shown differences between men and women in sensory hypersensitivity characteristics associated with neck/shoulder injuries. Taken together, the literature points to the importance of accounting for possible s/g differences at all levels of the biopsychosocial system in order to better understand sex- and gender-specific issues relevant to workplace health. PRACTITIONER SUMMARY: This article critically reviews recent literature and a conceptual model highlighting s/g differences in physical and functional characteristics related to neck/shoulder musculoskeletal disorders (NSMSD). Findings have implications on understanding how personal factors may affect NSMSD risk. With better understanding, practitioners can make more appropriate decisions to prevent work-related NSMSD.     

Maintenance of Response Readiness in Patients With Parkinson's Disease: Evidence From a Simple Reaction Time Task.

The authors explored the effect of Parkinson's disease (PD) on the generation and maintenance of response readiness in a simple reaction time task. They compared performance of idiopathic PD patients without dementia, age-matched controls, and younger controls over short (1-, 3-, and 6-s) and long (12- and 18-s) foreperiod intervals. After each trial, the authors probed memory for visual information that also had to be maintained during the trial interval. Patients and controls did not differ overall in their ability to maintain readiness over long delays. However, within the PD group only, errors in maintaining visual information were correlated with difficulty in maintaining readiness, suggesting that systems impaired in PD may facilitate the maintenance of processing in both motor and cognitive domains. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Concerted utility review of VVER-440 safety research needs (VERSAFE)

There are twelve operating VVER-440/213 reactors in the Czech Republic, Hungary and Slovakia. The plant owners have carried out extensive safety enhancement programmes, which have included measures to improve prevention, mitigation and control of design basis accidents. Recently, there have been a number of projects to study the Severe Accident Management aspects of these plants. The plant owners have also initiated Plant Life Management programmes. The objective of the VERSAFE Concerted Action is to create a network of the VVER-440/213 plant owners and operators, which aims at definition of the further research needs of severe accidents and plant ageing from the utilities’ viewpoint. The starting point is to formulate a general approach to severe accident management and plant life management and then proceed to define the needs for the additional information expected from the safety research. The role of national research institutes and organisations of the partner countries is of crucial importance in performing such research and, thus, creating and maintaining the expertise on the national level. The successful completion of the project will assist in establishing well-defined research projects that are oriented to the needs of the end-users and provide information that can be used to facilitate and support the negotiations of the EU applicant countries operating VVER-440 reactors.     

Coordinated dispatching of proximity sensors for the surveillance of manoeuvring targets

The surveillance of a manoeuvring target with multiple sensors in a coordinated manner requires a method for selecting and positioning groups of sensors in real time. Herein, the principles of dispatching, as used for the effective operation of service vehicles, are considered. The object trajectory is first discretized into a number of demand instants (data acquisition times), to which groups of sensors are assigned, respectively. Heuristic rules are used to determine the composition of each sensor group by evaluating the potential contribution of each sensor. In the case of dynamic sensors, the position of each sensor with respect to the target is also specified. Our proposed approach aims to improve the quality of the surveillance data in three ways: (1) The assigned sensors are manoeuvred into “optimal” sensing positions, (2) the uncertainty of the measured data is mitigated through sensor fusion, and (3) the poses of the unassigned sensors are adjusted to ensure that the surveillance system can react to future object manoeuvres. If a priori target trajectory information is available, the system performance may be further improved by optimizing the initial pose of each sensor off-line. The advantages of dispatching dynamic sensors over similar static-sensor systems are demonstrated through comprehensive simulations.     

Sensitivity of CFP/YFP and GFP/mCherry pairs to donor photobleaching on FRET determination by fluorescence lifetime imaging microscopy in living cells

Fluorescent protein-based FRET is a powerful method for visualizing protein-protein interactions and biochemical reactions in living cells. It can be difficult, however, to avoid photobleaching when observing fluorescent cells under the microscope, especially those expressing CFP. We compared the sensitivity of two protein-based FRET pairs to light-induced fluorescence changes in the donor, on FRET determination by fluorescence lifetime imaging microscopy (FLIM). Thanks to the very low excitation light levels of the time- and space-correlated single photon counting (TSCSPC) method, FLIM acquisitions were achieved without donor photobleaching. Here, we show that photobleaching of CFP by a mercury lamp under the microscope induced a decrease in the mean fluorescence lifetime, which interfered with FRET determination between CFP and YFP. Importantly, the range of light-induced variation of the mean fluorescence lifetime of CFP was not proportional to the decrease in the steady state fluorescence intensity and varied from cell to cell. The choice of the CFP/YFP pair therefore requires that the cells be observed and analyzed at very low light levels during the whole FRET experiment. In contrast, the GFP/mCherry pair provided an accurate FRET measurement by FLIM, even if some GFP photobleaching took place. We thus demonstrate that CFP can be an unreliable donor for FRET determination in living cells, due to its photosensitivity properties. We demonstrate that the GFP/mCherry pair is better suited for FRET measurement by FLIM in living cells than the CFP/YFP pair.     

Biosorption of Acid Red P-2BX by lichens as low-cost biosorbents

The aim of this study is to examine the dye biosorption properties of lichen species called Cladonia convoluta and Evernia prunastri. Since lichens are extensively found in the environment, their suitability as a cheap adsorbent has been investigated in this study. The optimal parameters for textile dye biosorption were also determined. The dried lichen biomass showed better dye biosorption capacity than ash lichen biomass. C. convoluta had better dye biosorption capacity than E. prunastri. Dye biosorption rate was found as 71.41% at optimal conditions. This study concluded that C. convoluta was a successful and cheap biosorbent for treatment of water contaminated by Acid Red P-2BX dye.     

Mechanical properties of submicronic and nanometric boron carbides obtained by Spark Plasma Sintering: Influence of B/C ratio and oxygen content

Boron carbide samples exhibiting nanometric and submicronic microstructure were sintered by Spark Plasma Sintering to investigate the effect of grain size on mechanical properties. The mechanical properties of sintered monoliths were characterized at the grain and macroscopic scales. Although nanostructured material exhibits finer grains than the submicronic material (i.e. mean diameter of 82 vs. 474?nm), its apparent rigidity and hardness are found to be reduced by 6.8% and 8.4% respectively. This contradiction with the Hall-Petch law is linked to the chemical compositions of both materials, which show significant difference in terms of B/C ratio and higher structural oxygen content especially for nanostructured material.     

Mechanical properties of freely suspended semiconducting graphene-like layers based on MoS2

We fabricate freely suspended nanosheets of molybdenum disulphide (MoS₂) which are characterized by quantitative optical microscopy and high-resolution friction force microscopy. We study the elastic deformation of freely suspended nanosheets of MoS₂ using an atomic force microscope. The Young''s modulus and the initial pre-tension of the nanosheets are determined by performing a nanoscopic version of a bending test experiment. MoS₂ sheets show high elasticity and an extremely high Young''s modulus (0.30 TPa, 50% larger than steel). These results make them a potential alternative to graphene in applications requiring flexible semiconductor materials.PACS, 73.61.Le, other inorganic semiconductors, 68.65.Ac, multilayers, 62.20.de, elastic moduli, 81.40.Jj, elasticity and anelasticity, stress-strain relations.