Barriers to the adoption of an energy efficient technology

Solid state electronic ballasts promise significant energy savings in the lighting systems of large buildings. However, organizational factors and standard operating procedures may inhibit the adoption of this technology in the large, bureaucratic public and private sector organizations which represent the major potential users of this technology.     

Levels of functional impairment following a civilian disaster: The Beverly Hills Supper Club fire.

117 individuals (mean age 37.77 yrs) who were at the fire and 30 individuals (mean age 40.72 yrs) who were not at the fire (bereaved families and rescue workers) were assessed regarding objective stressfulness of their fire experience, subjective stressfulness, and intensity of psychological symptoms (the Psychiatric Evaluation Form, PEF) in a structured clinical interview approximately 1 yr after the fire. Ss also filled out the Symptom Checklist-90, Revised Version (SCL-90R). 88 Ss were followed-up at 2 yrs. The group as a whole was more impaired than comparison samples of normals but less impaired than outpatients. Ss at the fire were less impaired than those not at the fire, who were similar to outpatients on the PEF. The latter group improved significantly on several measures from 1 to 2 yrs postfire, whereas the group at the fire showed little change. Results are discussed in the context of the specific instruments and methodology used in the present study, impairment levels of other samples, and the nature of the particular disaster. (19 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Therapist attitudes as influenced by A-B therapist type, patient diagnosis, and social class.

Attempted to clarify a number of inconsistent and contradictory findings regarding interactions between patient diagnosis (schizophrenic vs. neurotic) and the A-B therapist variable. 37 psychiatric residents completed Kemp's version of the A-B scale. The 10 highest and 10 lowest scorers then rated 4 patient vignettes on likability, discomfort, interest in treating, and prognosis. Patient social class as well as diagnosis were systematically controlled. Results support some of the previous research on likability but provided no support for other A-B * Patient Type interactions. A number of main effects for diagnosis and social class indicate that, in general, residents of both types hold more favorable attitudes toward neurotic and middle-class patients than they do toward schizophrenic and lower-class patients. (23 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Characterizing the NLRP3 Inflammasome in Mood Disorders: Overview,Technical Development,and Measures of Peripheral Activation in Adolescent Patients

The NOD-, LRR-, and pyrin-domain-containing protein 3 (NLRP3) inflammasome is a node of intracellular stress pathways and a druggable target which integrates mitochondrial stress and inflammatory cascades. While a body of evidence suggests the involvement of the NLRP3 inflammasome in numerous diseases, a lack of reliable measurement techniques highlights the need for a robust assay using small quantities of biological samples. We present a literature overview on peripheral activation of the NLRP3 inflammasome in mood disorders, then outline a process to develop and validate a robust assay to measure baseline and activated intracellular levels of “apoptosis-associated speck-like protein containing a CARD” (ASC) as a key component of an inflammatory profile in peripheral blood mononuclear cells (PBMC). A consistent association between high NLRP3 mRNA levels and relevant cytokines was seen in the literature. Using our method to measure ASC, stimulation of PBMC with lipopolysaccharide and nigericin or adenosine triphosphate resulted in microscopic identification of intracellular ASC specks, as well as interleukin 1 (IL-1) beta and caspase-1 p10 in the periphery. This was abolished by dose-dependent pre-treatment with 100 nM MCC950. We also report the use of this technique in a small pilot sample from patients with bipolar disorder and depressive disorders. The results show that levels of intracellular ASC and IL-1 beta are sensitive to change upon activation and maintained over time, which may be used to improve the detection of NLRP3 activation and guide personalized therapeutic strategy in the treatment of patients.     

Gas Chromatography with Flame Ionization Detection of 1,4-Dioxane in Palm-Based Fatty Alcohol Ethoxylates

During the ethoxylation of fatty alcohol, 1,4-dioxane, a toxic by-product may be formed. A simple and rapid method using gas chromatography with a flame ionization detector was developed for detection of 1,4-dioxane in commercial palm-based fatty alcohol ethoxylate (FAEO). The method involved spiking the 1,4-dioxane into FAEO samples, and directly injecting the spiked samples into GC with no clean-up steps. The method was validated in terms of linearity, accuracy, intra-day precision and inter-day precision, selectivity, limit of detection and limit of quantification. In terms of linearity, a calibration curve with a correlation coefficient of 0.9999 was obtained. The accuracy of the method was indicated by recovery obtained for spiked 1,4-dioxane samples at 5 levels of spiking, i.e. at 30, 60, 100, 200 and 500 μg/g, where recoveries were within 99–105 % with relative standard deviation (RSD) of <4.0 %. The RSD values of the intra-day and inter-day precision were <1.0 %. The limit of detection and quantification was 10 and 30 μg/g, respectively. The selectivity of the method was indicated by its ability to analyze commercial FAEO samples with different average moles of ethylene oxide (EO). The GC profiles of these FAEO with varying numbers of moles of EO were similar, and there were no other peaks interfering with the 1,4-dioxane peak.     

Masculine gender roles and counseling-related variables: Links with and mediation by personality.

The authors examined the overlap of masculine gender-role conflict and stress with personality, as organized in the 5-factor model (FFM), in a sample of 300 college men. Using a subset (n?=?173) of the total sample, the authors also revisited previously established relations of masculine gender-role conflict and stress with several counseling-related variables; there was a specific focus on the mediational role of personality in these relations. Results indicated that personality and masculine gender-role variables had 60% overlapping variance and that personality mediated 94% of the significant relations between masculinity and counseling-related variables. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

How users perceive and respond to security messages: a NeuroIS research agenda and empirical study

Users are vital to the information security of organizations. In spite of technical safeguards, users make many critical security decisions. An example is users’ responses to security messages – discrete communication designed to persuade users to either impair or improve their security status. Research shows that although users are highly susceptible to malicious messages (e.g., phishing attacks), they are highly resistant to protective messages such as security warnings. Research is therefore needed to better understand how users perceive and respond to security messages. In this article, we argue for the potential of NeuroIS – cognitive neuroscience applied to Information Systems – to shed new light on users’ reception of security messages in the areas of (1) habituation, (2) stress, (3) fear, and (4) dual-task interference. We present an illustrative study that shows the value of using NeuroIS to investigate one of our research questions. This example uses eye tracking to gain unique insight into how habituation occurs when people repeatedly view security messages, allowing us to design more effective security messages. Our results indicate that the eye movement-based memory (EMM) effect is a cause of habituation to security messages – a phenomenon in which people unconsciously scrutinize stimuli that they have previously seen less than other stimuli. We show that after only a few exposures to a warning, this neural aspect of habituation sets in rapidly, and continues with further repetitions. We also created a polymorphic warning that continually updates its appearance and found that it is effective in substantially reducing the rate of habituation as measured by the EMM effect. Our research agenda and empirical example demonstrate the promise of using NeuroIS to gain novel insight into users’ responses to security messages that will encourage more secure user behaviors and facilitate more effective security message designs.     

Why older adults make more immediate treatment decisions about cancer than younger adults.

Literature relevant to medical decision making was reviewed, and a model was outlined for testing. Two studies examined whether older adults make more immediate decisions than younger adults about treatments for prostate or breast cancer in authentic scenarios. Findings clearly showed that older adults were more likely to make immediate decisions than younger adults. The research is important because it not only demonstrates the consistency of this age-related effect across disease domains, gender, ethnic groups, and prevalent education levels but begins to investigate a model to explain the effect. Major reasons for the effect focus on treatment knowledge, interest and engagement, and cognitive resources. Treatment knowledge, general cancer knowledge, interest, and cognitive resources relate to different ways of processing treatment information and preferences for immediate versus delayed decision making. Adults with high knowledge of treatments on a reliable test tended to make immediate treatment decisions, which supports the knowledge explanation. Adults with more cognitive resources and more interest tended to delay their treatment decisions. Little support was found for a cohort explanation for the relationship between age and preference for immediate medical decision making. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Fluoxetine, smoking, and history of major depression: A randomized controlled trial.

The study was a randomized placebo-controlled trial testing whether fluoxetine selectively enhances cessation for smokers with a history of depression. Euthymic smokers with (H+, n = 109) or without (H-, n = 138) a history of major depression received 60 mg fluoxetine or placebo plus group behavioral quit-smoking treatment for 12 weeks. Fluoxetine initially enhanced cessation for H+ smokers (p = .02) but subsequently impaired cessation regardless of depressive history. Six months after quit date, fluoxetine-treated participants were 3.3 times more likely to be smoking (p = .02). Further research is warranted to determine why high-dose fluoxetine produces continuing effects that oppose tobacco abstinence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Objectification theory and deaf cultural identity attitudes: Roles in deaf women's eating disorder symptomatology.

This study examined the generalizability of direct and mediated links posited in objectification theory among internalization of sociocultural standards of beauty, body surveillance, body shame, and eating disorder symptoms with a sample of Deaf women. The study also examined the role of marginal Deaf cultural identity attitudes within this framework. Data from 177 Deaf women indicated positive relations among internalization, body surveillance, body shame, and eating disorder symptomatology. Consistent with tenets of objectification theory, body shame mediated the links of internalization and body surveillance with eating disorder symptoms. In addition, marginal Deaf identity attitudes (but not hearing, immersion, or bicultural attitudes) were linked uniquely with eating disorder constructs and had significant indirect relations through internalization with body surveillance, body shame, and eating disorder symptoms. Implications for practice and future research are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)