全文获取类型
收费全文 | 444篇 |
免费 | 10篇 |
专业分类
电工技术 | 3篇 |
综合类 | 2篇 |
化学工业 | 134篇 |
金属工艺 | 12篇 |
机械仪表 | 5篇 |
建筑科学 | 27篇 |
矿业工程 | 1篇 |
能源动力 | 6篇 |
轻工业 | 31篇 |
石油天然气 | 2篇 |
无线电 | 40篇 |
一般工业技术 | 72篇 |
冶金工业 | 33篇 |
原子能技术 | 2篇 |
自动化技术 | 84篇 |
出版年
2023年 | 4篇 |
2022年 | 9篇 |
2021年 | 13篇 |
2019年 | 6篇 |
2018年 | 13篇 |
2017年 | 7篇 |
2016年 | 8篇 |
2015年 | 12篇 |
2014年 | 12篇 |
2013年 | 23篇 |
2012年 | 12篇 |
2011年 | 27篇 |
2010年 | 22篇 |
2009年 | 19篇 |
2008年 | 23篇 |
2007年 | 16篇 |
2006年 | 14篇 |
2005年 | 15篇 |
2004年 | 13篇 |
2003年 | 10篇 |
2002年 | 9篇 |
2001年 | 3篇 |
2000年 | 7篇 |
1999年 | 12篇 |
1998年 | 12篇 |
1997年 | 14篇 |
1996年 | 13篇 |
1995年 | 10篇 |
1994年 | 10篇 |
1993年 | 4篇 |
1992年 | 3篇 |
1991年 | 4篇 |
1990年 | 7篇 |
1989年 | 3篇 |
1988年 | 3篇 |
1987年 | 2篇 |
1986年 | 5篇 |
1985年 | 7篇 |
1984年 | 3篇 |
1983年 | 3篇 |
1980年 | 5篇 |
1979年 | 2篇 |
1978年 | 5篇 |
1977年 | 9篇 |
1976年 | 6篇 |
1975年 | 7篇 |
1970年 | 1篇 |
1969年 | 1篇 |
1959年 | 1篇 |
1941年 | 1篇 |
排序方式: 共有454条查询结果,搜索用时 0 毫秒
91.
Dietrich Braun Burkhard Schmiedel Gtz P. Hellmann Morand Lambla Michael Schneider 《大分子材料与工程》1998,254(1):79-84
Natural latex (NR) particles, modified with a hard shell of poly(methyl methacrylate) (PMMA) and with a substructure of PMMA (type "NR-M") or polystyrene (type "NR-SM"), were tested as compatibilizers in blends of polycarbonate (of bisphenol A, PC) and PMMA or PS. During melt blending, the modified NR particles were torn apart, from an original size of >0.5 μm down to ≅0.1 μm in diameter. Two different types of particle distribution were observed in the blends: in PC/PMMA/NR-M blends, the NR-M particles were dispersed in the PMMA phase, whereas, in PC/PS/NR-SM blends, the NR-SM particles formed interface layers between PC and PS phase domains. The latter blend morphology, distinguished by continuous rubbery interface layers of NR-SM, turned out to be mechanically excellent in injection-moulded parts. The poor impact strength of PC/PS was raised by an order of magnitude. The effect depends on the orientation in the injection-moulded test bars. 相似文献
92.
Malte Steiner Lutz Claes Anita Ignatius Frank Niemeyer Ulrich Simon Tim Wehner 《Journal of the Royal Society Interface》2013,10(86)
Numerical models of secondary fracture healing are based on mechanoregulatory algorithms that use distortional strain alone or in combination with either dilatational strain or fluid velocity as determining stimuli for tissue differentiation and development. Comparison of these algorithms has previously suggested that healing processes under torsional rotational loading can only be properly simulated by considering fluid velocity and deviatoric strain as the regulatory stimuli. We hypothesize that sufficient calibration on uncertain input parameters will enhance our existing model, which uses distortional and dilatational strains as determining stimuli, to properly simulate fracture healing under various loading conditions including also torsional rotation. Therefore, we minimized the difference between numerically simulated and experimentally measured courses of interfragmentary movements of two axial compressive cases and two shear load cases (torsional and translational) by varying several input parameter values within their predefined bounds. The calibrated model was then qualitatively evaluated on the ability to predict physiological changes of spatial and temporal tissue distributions, based on respective in vivo data. Finally, we corroborated the model on five additional axial compressive and one asymmetrical bending load case. We conclude that our model, using distortional and dilatational strains as determining stimuli, is able to simulate fracture-healing processes not only under axial compression and torsional rotation but also under translational shear and asymmetrical bending loading conditions. 相似文献
93.
Dayon L Hainard A Licker V Turck N Kuhn K Hochstrasser DF Burkhard PR Sanchez JC 《Analytical chemistry》2008,80(8):2921-2931
A new 6-plex isobaric mass tagging technology is presented, and proof of principle studies are carried out using standard protein mixtures and human cerebrospinal fluid (CSF) samples. The Tandem Mass Tags (TMT) comprise a set of structurally identical tags which label peptides on free amino-terminus and epsilon-amino functions of lysine residues. During MS/MS fragmentation, quantification information is obtained through the losses of the reporter ions. After evaluation of the relative quantification with the 6-plex version of the TMT on a model protein mixture at various concentrations, the quantification of proteins in CSF samples was performed using shotgun methods. Human postmortem (PM) CSF was taken as a model of massive brain injury and comparison was carried out with antemortem (AM) CSF. After immunoaffinity depletion, triplicates of AM and PM CSF pooled samples were reduced, alkylated, digested by trypsin, and labeled, respectively, with the six isobaric variants of the TMT (with reporter ions from m/z = 126.1 to 131.1 Th). The samples were pooled and fractionated by SCX chromatography. After RP-LC separation, peptides were identified and quantified by MS/MS analysis with MALDI TOF/TOF and ESI-Q-TOF. The concentration of 78 identified proteins was shown to be clearly increased in PM CSF samples compared to AM. Some of these proteins, like GFAP, protein S100B, and PARK7, have been previously described as brain damage biomarkers, supporting the PM CSF as a valid model of brain insult. ELISA for these proteins confirmed their elevated concentration in PM CSF. This work demonstrates the validity and robustness of the tandem mass tag (TMT) approach for quantitative MS-based proteomics. 相似文献
94.
Manfred Lamprecht Simon Bogner Gert Schippinger Kurt Steinbauer Florian Fankhauser Seth Hallstroem Burkhard Schuetz Joachim F Greilberger 《Journal of the International Society of Sports Nutrition》2012,9(1):1-13
Background
Probiotics are an upcoming group of nutraceuticals claiming positive effects on athlete??s gut health, redox biology and immunity but there is lack of evidence to support these statements.Methods
We conducted a randomized, double-blinded, placebo controlled trial to observe effects of probiotic supplementation on markers of intestinal barrier, oxidation and inflammation, at rest and after intense exercise. 23 trained men received multi-species probiotics (1010 CFU/day, Ecologic?Performance or OMNi-BiOTiC?POWER, n?=?11) or placebo (n?=?12) for 14?weeks and performed an intense cycle ergometry over 90 minutes at baseline and after 14?weeks. Zonulin and ??1-antitrypsin were measured from feces to estimate gut leakage at baseline and at the end of treatment. Venous blood was collected at baseline and after 14?weeks, before and immediately post exercise, to determine carbonyl proteins (CP), malondialdehyde (MDA), total oxidation status of lipids (TOS), tumor necrosis factor-alpha (TNF-??), and interleukin-6 (IL-6). Statistical analysis used multifactorial analysis of variance (ANOVA). Level of significance was set at p?<?0.05, a trend at p?<?0.1.Results
Zonulin decreased with supplementation from values slightly above normal into normal ranges (<30?ng/ml) and was significantly lower after 14?weeks with probiotics compared to placebo (p?=?0.019). We observed no influence on ??1-antitrypsin (p?>?0.1). CP increased significantly from pre to post exercise in both groups at baseline and in the placebo group after 14?weeks of treatment (p?=?0.006). After 14?weeks, CP concentrations were tendentially lower with probiotics (p?=?0.061). TOS was slightly increased above normal in both groups, at baseline and after 14?weeks of treatment. There was no effect of supplementation or exercise on TOS. At baseline, both groups showed considerably higher TNF-?? concentrations than normal. After 14?weeks TNF-?? was tendentially lower in the supplemented group (p?=?0.054). IL-6 increased significantly from pre to post exercise in both groups (p?=?0.001), but supplementation had no effect. MDA was not influenced, neither by supplementation nor by exercise.Conclusions
The probiotic treatment decreased Zonulin in feces, a marker indicating enhanced gut permeability. Moreover, probiotic supplementation beneficially affected TNF-?? and exercise induced protein oxidation. These results demonstrate promising benefits for probiotic use in trained men.Clinical trial registry
http://www.clinicaltrials.gov, identifier: NCT01474629 相似文献95.
Andreas Hohenleutner Susanna Schmidbauer Rudolf Vasold Dominik Joosten Philipp Stoessel Herwig Buchholz Burkhard König 《Advanced functional materials》2012,22(16):3406-3413
This work reports the combinatorial synthesis and screening of phosphorescent iridium complexes as solution processable emitters for OLEDs. The approach taken here allows for the rapid synthesis, isolation, spectroscopic characterization and identification of the libraries based on chromatographic methods. Subsequent analysis of the irradiation induced degradation provides insight on the stability of the complexes under continuous excitation. The method is versatile and can easily be applied to other metal complexes or organic dyes for various applications, e.g., in electroluminescence, photovoltaics and sensing. 相似文献
96.
97.
98.
Andreas Birk Burkhard Wiggerich Heiko Bülow Max Pfingsthorn Sören Schwertfeger 《Journal of Intelligent and Robotic Systems》2011,64(1):57-76
Several missions with an Unmanned Aerial Vehicle (UAV) in different realistic safety, security, and rescue field tests are
presented. First, results from two safety and security missions at the 2009 European Land Robot Trials (ELROB) are presented.
A UAV in form of an Airrobot AR100-B is used in a reconnaissance and in a camp security scenario. The UAV is capable of autonomous
waypoint navigation using onboard GPS processing. A digital video stream from the vehicle is used to create photo maps—also
known as mosaicking—in real time at the operator station. This mapping is done using an enhanced version of Fourier Mellin
based registration, which turns out to be very fast and robust. Furthermore, results from a rescue oriented scenario at the
2010 Response Robot Evaluation Exercises (RREE) at Disaster City, Texas are presented. The registration for the aerial mosaicking
is supplemented by an uncertainty metric and embedded into Simultaneous Localization and Mapping (SLAM), which further enhances
the photo maps as main mission deliveries. 相似文献
99.
Genome-Wide Investigation of Multifocal and Unifocal Prostate Cancer—Are They Genetically Different?
Chinyere Ibeawuchi Hartmut Schmidt Reinhard Voss Ulf Titze Mahmoud Abbas Joerg Neumann Elke Eltze Agnes Marije Hoogland Guido Jenster Burkhard Brandt Axel Semjonow 《International journal of molecular sciences》2013,14(6):11816-11829
Prostate cancer is widely observed to be biologically heterogeneous. Its heterogeneity is manifested histologically as multifocal prostate cancer, which is observed more frequently than unifocal prostate cancer. The clinical and prognostic significance of either focal cancer type is not fully established. To investigate prostate cancer heterogeneity, the genetic profiles of multifocal and unifocal prostate cancers were compared. Here, we report observations deduced from tumor-tumor comparison of copy number alteration data of both focal categories. Forty-one fresh frozen prostate cancer foci from 14 multifocal prostate cancers and eight unifocal prostate cancers were subjected to copy number variation analysis with the Affymetrix SNP 6.0 microarray tool. With the investigated cases, tumors obtained from a single prostate exhibited different genetic profiles of variable degrees. Further comparison identified no distinct genetic pattern or signatures specific to multifocal or unifocal prostate cancer. Our findings suggest that samples obtained from multiple sites of a single unifocal prostate cancer show as much genetic heterogeneity and variability as separate tumors obtained from a single multifocal prostate cancer. 相似文献
100.
Matthias Siemon Olaf Riese Burkhard Forell Dominic Krnung Walter Klein‐Heßling 《火与材料》2019,43(5):497-513
In the context of industrial buildings and power plants, electrical installations and cable trays represent a main fuel load and a potential initial fire source due to possible short circuits or comparable malfunction. Furthermore, a fire can spread from one tray to additional trays mounted above and/or horizontally on one tray. Because of the high significance of cable fires, several research projects have been carried out, investigating the fire behaviour of cables from small‐scale tests, eg, the cone calorimeter, up to large‐scale tests, analysing complete cable tray constructions. The goal of the work presented in this paper is the extension of the knowledge regarding the influence of geometrical parameters like the packing density and tray distance on the burning behaviour and fire spread of cable tray installations. The results are considered, together with test results from the literature, to quantify the main physical parameters describing the burning behaviour. In a next step, the general applicability of these parameters as input data for the parametrization of the source term of numerical simulations is shown. The test results show that the burning behaviour and the fire spreading highly depend on the cable arrangement of the cables on the cable tray, in combination with other boundary conditions. By applying the results as input for a fire simulation, the mass loss rate is considered appropriately. 相似文献