The Nyquist robust sensitivity margin for uncertain closed‐loop systems

The Nyquist robust sensitivity margin is proposed as a new scalar indicator of robust stability that also provides a meaningful quantitative assessment of the worst sensitivity realized by the uncertain closed loop. After formulating and discussing in detail the underlying optimization problem required for the calculation of the margin, the approach is applied to the characterization of the robust stability of a closed‐loop featuring a linear system with an affine uncertainty structure and a parametric uncertainty set described by a real rectangular polytope. The capabilities of the methodology are illustrated through examples, which include an approach for quantifying alternative robustness margins, such as a parametric stability margin. The computational algorithm is systematic and can be carried out with high numerical precision. Copyright © 2005 John Wiley & Sons, Ltd.     

An approach for high-yield requirements capture for e-commerce and its application

Web-based e-commerce software is typically real-time, responsive, and distributed software that must meet high quality requirements. Moreover, because of its Internet-based operating environment, e-commerce software must deal with concurrency, synchronization, and non-deterministic issues (such as delays) primarily caused by the heavy usage load and underlying network conditions. In this paper, we introduce a generic, cost-effective approach to optimize requirements capture (and subsequent development and testing) with respect to functional coverage and customer perception of quality. This high-yield approach is presented and illustrated by application to an e-commerce online shopping system and used to explain the principles of use-case requirements captured in the unified modeling language. Published online: 25 July 2001     

Effect of dead space on gain and noise ofdouble-carrier-multiplication avalanche photodiodes

The effect of dead space on the statistics of the gain in a double-carrier-multiplication avalanche photodiode (APD) is determined using a recurrence method. The dead space is the minimum distance that a newly generated carrier must travel in order to acquire sufficient energy to become capable of causing an impact ionization. Recurrence equations are derived for the first moment, the second moment, and the probability distribution function of two random variables that are related, in a deterministic way, to the random gain of the APD. These equations are solved numerically to produce the mean gain and the excess noise factor. The presence of dead space reduces both the mean gain and the excess noise factor of the device. This may have a beneficial effect on the performance of the detector when used in optical receivers with photon noise and circuit noise     

Dissolution Rates of Commercial Phenylbutazone Tablets: Inter-And Intra-Brand Effects

A study has been carried out to investigate the dissolution rate profiles of twelve batches of sugar-coated phenylbutazone tablets belonging to four commercial brands. Using the rotating basket method, significant inter-brand and inter-batch variations in dissolution rates were found. Only two batches of one brand passed the B.P. dissolution limit whilst other batches had percentages dissolution between 0.3 and 58 after 45 min. Batches with poor dissolution characteristics exhibited significant tablet-to-tablet variations in dissolution rates; a finding which was not observed in the relatively fast-dissolving batches. When the paddle method was substituted for the B.P. basket method, the dissolution rates were relatively faster but similar dissolution failure was found. However, the tablet-to-tablet dissolution variability was decreased in some of the batches. The observed differences in dissolution rates of the batches examined were unrelated to their disintegration times. Inspite of the poor dissolution characteristics of most of the batches studied, no apparent chemical degradation was found. It is recommended that when evaluating the dissolution rates of brands of phenylbutazone tablets, a number of batches from each brand should be tested.     

Isolated agenesis of the mastoid antrum

The first isolated case of agenesis of the mastoid antrum, previously only described in association with the congenital syndromes trisomy 13 and mandibulofacial dysostosis, is reported. The loss of this important surgical landmark may result in disorientation and iatrogenic trauma. The surgeon must be aware of its existence, and where it is suspected the middle fossa dura should be exposed and followed posteriorly until the lateral sinus is encountered.     

Real-Time Testing of WPT-Based Protection of Three-Phase VS PWM Inverter-Fed Motors

This paper presents an experimental testing of a wavelet packet transform (WPT)-based technique for protecting and controlling three-phase voltage-source (VS) pulse-width modulated (PWM) inverters under extreme load conditions. The proposed technique is based on a two-level multiresolution analysis (MRA) applied on output currents of a 3Phi VS PWM inverter. The MRA aims to extract certain signatures, which are the second level highest frequency subband coefficients. These coefficients take a nonzero value for any signal that is short-duration, nonperiodic and nonstationary with impulse-super imposed high frequencies. Such a signal perfectly matches a current arising from any typical fault occurring in either the inverter legs or on the load side. The proposed technique is realized using a -code hosted and executed by a dSPACE ds1102 controller board. The tested inverter supplies loads that include a 3Phi Y-connected R - L load, a 3Phi squirrel-cage induction motor and a 3Phi synchronous reluctance motor. The extreme load conditions include inverter open-leg, motor starting currents and different faults in motor stator windings. The experimental test results show accurate, fast, and effective response to all disturbances including fault currents by the proposed WPT-based technique.     

A segmentation approach for file broadcast scheduling

We study the broadcast scheduling problem in which clients send their requests to a server in order to receive some files available on the server. The server may be scheduled in a way that several requests are satisfied in one broadcast. When files are transmitted over computer networks, broadcasting the files by fragmenting them provides flexibility in broadcast scheduling that allows the optimization of per user response time. The broadcast scheduling algorithm, then, is in charge of determining the number of segments of each file and their order of transmission in each round of transmission. In this paper, we obtain a closed form approximation formula which approximates the optimal number of segments for each file, aiming at minimizing the total response time of requests. The obtained formula is a function of different parameters including those of underlying network as well as those of requests arrived at the server. Based on the obtained approximation formula we propose an algorithm for file broadcast scheduling which leads to total response time which closely conforms to the optimum one. We use extensive simulation and numerical study in order to evaluate the proposed algorithm which reveals high accuracy of obtained analytical approximation. We also investigate the impact of various headers that different network protocols add to each file segment. Our segmentation approach is examined for scenarios with different file sizes at the range of 100 KB to 1 GB. Our results show that for this range of file sizes the segmentation approach shows on average 13% tolerance from that of optimum in terms of total response time and the accuracy of the proposed approach is growing by increasing file size. Besides, using proposed segmentation in this work leads to a high Goodput of the scheduling algorithm.     

Performance of glass fiber reinforced polymer bars under elevated temperatures

This paper investigates the residual tensile properties of newly developed glass fiber reinforced polymer (GFRP) bars after being subjected to elevated temperatures for different periods. A total of 120 GFRP specimens were tested in this study. Half of the samples were covered with concrete while the other half were bare bars. The specimens were subjected to three different controlled temperatures (100, 200 and 300 °C) for three different periods (1, 2, and 3 h). Test results showed that almost no losses were observed in the tensile modulus after all exposure periods and temperatures. Losses in the tensile strength, proportional to the level of temperature and exposure period, were recorded. The bars with concrete cover showed higher residual tensile strength compared to their counterparts without coating. The concrete cover was more effective at the lowest temperature level (100 °C) and at the shortest time period (1 h). Scanning Electronic Microscopy (SEM) technique was also used to investigate the effect of elevated temperature on the degradation mechanism of the GFRP bars. The results showed that increasing the temperature level affected the resin matrix surrounding the glass fibers and consequently affected the bond between the fibers and the matrix.     

Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade

Developmental neurotoxicity caused by chlorpyrifos exposure is generally thought to target cholinesterase but chlorpyrifos may also act on cellular intermediates, such as adenylyl cyclase, that serve global functions in the coordination of cell development. In the current study, neonatal rats were exposed to apparently subtoxic doses of chlorpyrifos (no weight loss, no mortality) either on Postnatal Days 1-4 or on Postnatal Days 11-14, and the effects on components of the adenylyl cyclase cascade were evaluated in brain regions that are enriched (forebrain) or sparse (cerebellum) in cholinergic innervation, as well as in a nonneural tissue (heart). In all three, chlorpyrifos evoked deficits in multiple components of the adenylyl cyclase cascade: expression and activity of adenylyl cyclase itself, functioning of G-proteins that link neurotransmitter and hormone receptors to cyclase activity, and expression of neurotransmitter receptors that act through this cascade. Disruption of signaling function was not restricted to transduction of cholinergic signals but rather extended to adrenergic signals as well. In most cases, the adverse effects were not evident during the immediate period of chlorpyrifos administration, but appeared after a delay of several days. These results suggest that chlorpyrifos can affect cell development by altering the activity and reactivity of the adenylyl cyclase signaling cascade, a major control point for trophic regulation of cell differentiation. The effects are not restricted to cholinergic targets, nor even to the central nervous system. Hence, disruption of cell development by chlorpyrifos is likely to be more widespread than previously thought.