运用PDCA循环提升企业保密工作水平

保密工作事关党和国家的安全,事关企业核心利益。随着经济全球化伴随着互联网信息技术的迅猛发展,企业间交流与合作日益增多,对保密工作也提出了新的更高要求。本文探讨运用PDCA循环提升企业保密工作水平的方法及步骤,并提出建议和措施。     

Therapeutic Effects of Insulin-Producing Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Type 1 Diabetes Mouse Model

In patients with type 1 diabetes (T1D), compromised pancreatic β-cell functions are compensated through daily insulin injections or the transplantation of pancreatic tissue or islet cells. However, both approaches are associated with specific challenges. The transplantation of mesenchymal stem cells (MSCs) represents a potential alternative, as MSCs have tissue-forming capacity and can be isolated from various tissues. The human umbilical cord (hUC) is a good source of freely available MSCs, which can be collected through pain-free, non-invasive methods subject to minimal ethical concerns. We sought to develop a method for the in vitro generation of insulin-producing cells (IPCs) using MSCs. We examined the potential therapeutic uses and efficacy of IPCs generated from hUC-derived MSCs (hUC-IPCs) and human adipose tissue (hAD)-derived MSCs (hAD-IPCs) through in vitro experiments and streptozotocin (STZ)-induced C57BL/6 T1D mouse models. We discovered that compared to hAD-IPCs, hUC-IPCs exhibited a superior insulin secretion capacity. Therefore, hUC-IPCs were selected as candidates for T1D cell therapy in mice. Fasting glucose and intraperitoneal glucose tolerance test levels were lower in hUC-IPC-transplanted mice than in T1D control mice and hAD-IPC-transplanted mice. Our findings support the potential use of MSCs for the treatment of T1D.     

基于多重自相关微弱正弦信号的检测

强噪音背景下检测出有用的正弦信号是信号检测中的一个典型问题。本文介绍的多重自相关法利用了正弦函数的特性,经过多重自相关运算,再对信号进行频谱分析,就能准确检测出湮没于强大噪声的微弱正弦信号,其中频率信息精确,幅值信息经过修正后也能达到一定精度。     

电站锅炉压力容器检验单位资质问题的现状及思考

文章回顾了电力行业锅监工作的历史及检验体系的建立,针对目前电站锅炉压力容器检验单位资质问题的现状,为了保证对电力安全生产及锅炉压力容器设备的安全稳定运行,对检验单位的资质问题进行了分析,并对目前以及将来的检验工作、检验单位的发展、检验市场的建立等提出了建设性的意见。     

Structure evolution,dielectric,and conductivity behavior of(K0.5Na0.5)NbO3-Bi(Zn2/3Nb1/3)O3 ceramics

(1-x)K0.5Na0.5NbO3-xBi(Zn2/3Nb1/3)O3 ((1-x)KNN-xBZN,x =0.010,0.015,0.020,0.025,and 0.030) lead-free ceramics were fabricated via a traditional solid-state metho...     

The E3 Ligase GmPUB21 Negatively Regulates Drought and Salinity Stress Response in Soybean

E3-ubiquitin ligases are known to confer abiotic stress responses in plants. In the present study, GmPUB21, a novel U-box E3-ubiquitin ligase-encoding gene, was isolated from soybean and functionally characterized. The expression of GmPUB21, which possesses E3-ubiquitin ligase activity, was found to be significantly up-regulated by drought, salinity, and ABA treatments. The fusion protein GmPUB21-GFP was localized in the cytoplasm, nucleus, and plasma membrane. Transgenic lines of the Nicotiana benthamiana over-expressing GmPUB21 showed more sensitive to osmotic, salinity stress and ABA in seed germination and inhibited mannitol/NaCl-mediated stomatal closure. Moreover, higher reactive oxygen species accumulation was observed in GmPUB21 overexpressing plants after drought and salinity treatment than in wild-type (WT) plants. Contrarily, silencing of GmPUB21 in soybean plants significantly enhanced the tolerance to drought and salinity stresses. Collectively, our results revealed that GmPUB21 negatively regulates the drought and salinity tolerance by increasing the stomatal density and aperture via the ABA signaling pathway. These findings improved our understanding of the role of GmPUB21 under drought and salinity stresses in soybean.     

Studies on Lotus Genomics and the Contribution to Its Breeding

Lotus (Nelumbo nucifera), under the Nelumbonaceae family, is one of the relict plants possessing important scientific research and economic values. Because of this, much attention has been paid to this species on both its biology and breeding among the scientific community. In the last decade, the genome of lotus has been sequenced, and several high-quality genome assemblies are available, which have significantly facilitated functional genomics studies in lotus. Meanwhile, re-sequencing of the natural and genetic populations along with different levels of omics studies have not only helped to classify the germplasm resources but also to identify the domestication of selected regions and genes controlling different horticultural traits. This review summarizes the latest progress of all these studies on lotus and discusses their potential application in lotus breeding.     

云南省碳酸盐岩地区水库的渗漏评价

1岩溶发育的时空分布 云南省主要岩溶分布：海拔高程2600～2700m称高原期;2350～2450m,2150～2250m,1900～2000m称石林期;小于1600m称金沙江期。这是几个大的地史时期,其间各地依据地方特点还有一些地方分期。     

土钉墙分步开挖中挡土机理分析

土钉墙和由它派生出的复合支护方式在实际工程中广泛应用,但在理论上对它的挡土机理研究还不够。本文对均质土中的土钉墙,采用数值分析方法,探讨开挖过程中土钉、面层、土体三者的受力变化及土钉墙的稳定机理,得到了面层受到的总土压力是主动土压力的0．05倍等一些结论。