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161.
G. E. Lucas 《Metallurgical and Materials Transactions A》1990,21(5):1105-1119
Small specimen test technology has evolved out of the necessity to develop and monitor materials proposed for or used in nuclear
power generation systems. Development of materials for improved cladding and in-core structures for fission reactors and assessment
of core materials and pressure vessel steels already under irradiation necessitated the use of specimens which fit into existing
irradiation space or which could be extracted from irradiated structures, such as cladding or ducts. Interest in simulating
neutron irradiation by light and heavy ion irradiation led to the development of thin foil and wire geometry specimens. Further,
interest in developing materials for fusion reactors has added additional constraints on specimen sizes associated with available
irradiation volumes in existing and proposed high-energy neutron irradiation facilities. Consequently, a wide array of specimen
geometries and test techniques has now been developed. It is the purpose of this paper to review these techniques and examine
their status, problems, and potential for future applications.
This paper is based on a presentation made in the symposium “Irradiation-Enhanced Materials Science and Engineering” presented
as part of the ASM INTERNATIONAL 75th Anniversary celebration at the 1988 World Materials Congress in Chicago, IL, September
25–29, 1988, under the auspices of the Nuclear Materials Committee of TMS-AIME and ASM-MSD. 相似文献
162.
Lucas J. Brickweg Bryce R. Floryancic Erik D. Sapper Raymond H. Fernando 《Journal of Coatings Technology and Research》2007,4(1):107-110
Atomic Force Microscopy and Scanning Electron Microscopy were used to study shear-induced alignment of alumina and silica
nanoparticles in two-component polyurethane clear coatings. 1-D strings of nanoparticles, formed in an extended pearl-necklace
fashion were observed near the surfaces of cured films at nanoparticle volume fractions less than 0.05. This alignment is
affected by the shear conditions of the application method. When applied by spraying, linear particle strings as long as 5 cm
were observed in the direction of shear. Nanoparticle strings were also found, to a lesser extent, when coatings were applied
by a drawdown method. The phenomenon was not observed in coatings applied with minimal shear. These particle string formations,
in addition to affecting the performance of coatings, may have broader implications in the field of nanomaterials. Our literature
searches so far have not uncovered reports of stable, 1-D nanoparticle arrangements with same degree of linearity produced
under simple shear with compositions having very low particle loadings.
Presented at the 2006 FutureCoat! conference, sponsored by the Federation of Societies for Coatings Technology, in New Orleans,
LA, on November 1–3, 2006. 相似文献
163.
Lucas M. Hale 《JOM Journal of the Minerals, Metals and Materials Society》2018,70(7):1100-1105
Multiple computational methods for modeling dislocations are implemented within a high-throughput calculation framework allowing for rigorous investigations comparing the methodologies. Focusing on aluminum edge dislocations, 21 classical aluminum interatomic potentials are used to directly model dislocation core structures using molecular dynamics and to provide input data for solving the semidiscrete variational Peierls–Nabarro dislocation model. The predicted dislocation core spreading obtained from both computational methods shows similar trends across the potentials. Additionally, tests are done to rigorously determine if a recent correction to the Peierls–Nabarro model results in better agreement with the atomistic calculations. 相似文献
164.
Priv. Doz. Dr. Felix Zelder Marjorie Sonnay Lucas Prieto 《Chembiochem : a European journal of chemical biology》2015,16(9):1264-1278
Antivitamins represent a broad class of compounds that counteract the essential effects of vitamins. The symptoms triggered by such antinutritional factors resemble those of vitamin deficiencies, but can be successfully reversed by treating patients with the intact vitamin. Despite being undesirable for healthy organisms, the toxicities of these compounds present considerable interest for biological and medicinal purposes. Indeed, antivitamins played fundamental roles in the development of pioneering antibiotic and antiproliferative drugs, such as prontosil and aminopterin. Their development and optimisation were made possible by the study, throughout the 20th century, of the vitamins' and antivitamins' functions in metabolic processes. However, even with this thorough knowledge, commercialised antivitamin‐based drugs are still nowadays limited to antagonists of vitamins B9 and K. The antivitamin field thus still needs to be explored more intensely, in view of the outstanding therapeutic success exhibited by several antivitamin‐based medicines. Here we summarise historical achievements and discuss critically recent developments, opportunities and potential limitations of the antivitamin approach, with a special focus on antivitamins K, B9 and B12. 相似文献
165.
Changes in actin and tubulin expression in osteogenic cells cultured on bioactive glass‐based surfaces 下载免费PDF全文
Carolina Scanavez Martins Emanuela Prado Ferraz Larissa Moreira Spinola De Castro‐Raucci Lucas Novaes Teixeira William Marcatti Amarú Maximiano Adalberto Luiz Rosa Paulo Tambasco De Oliveira 《Microscopy research and technique》2015,78(11):1046-1053
The present study evaluated whether the changes in the labeling pattern of cytoskeletal proteins in osteogenic cells cultured on bioactive glass‐based materials are due to altered mRNA and protein levels. Primary rat‐derived osteogenic cells were plated on Bioglass® 45S5, Biosilicate®, and borosilicate (bioinert control). The following parameters were assayed: (i) qualitative epifluorescence analysis of actin and tubulin; (ii) quantitative mRNA and protein expression for actin and tubulin by real‐time PCR and ELISA, respectively, and (iii) qualitative analysis of cell morphology by scanning electron microscopy (SEM). At days 3 and 7, the cells grown on borosilicate showed typical actin and tubulin labeling patterns, whereas those on the bioactive materials showed roundish areas devoid of fluorescence signals. The cultures grown on bioactive materials showed significant changes in actin and tubulin mRNA expression that were not reflected in the corresponding protein levels. A positive correlation between the mRNA and protein as well as an association between epifluorescence imaging and quantitative data were only detected for the borosilicate. SEM imaging of the cultures on the bioactive surfaces revealed cells partly or totally coated with material aggregates, whose characteristics resembled the substrate topography. The culturing of osteogenic cells on Bioglass® 45S5 and Biosilicate® affect actin and tubulin mRNA expression but not the corresponding protein levels. Changes in the labeling pattern of these proteins should then be attributed, at least in part, to the presence of a physical barrier on the cell surface as a result of the material surface reactions, thus limiting fluorescence signals. Microsc. Res. Tech. 78:1046–1053, 2015. © 2015 Wiley Periodicals, Inc. 相似文献
166.
Qingpeng Niu James Dinan Sravya Tirukkovalur Anouar Benali Jeongnim Kim Lubos Mitas Lucas Wagner P. Sadayappan 《Concurrency and Computation》2016,28(13):3655-3671
Quantum Monte Carlo (QMC) applications perform simulation with respect to an initial state of the quantum mechanical system, which is often captured by using a cubic B‐spline basis. This representation is stored as a read‐only table of coefficients and accesses to the table are generated at random as part of the Monte Carlo simulation. Current QMC applications, such as QWalk and QMCPACK, replicate this table at every process or node, which limits scalability because increasing the number of processors does not enable larger systems to be run. We present a partitioned global address space approach to transparently managing this data using Global Arrays in a manner that allows the memory of multiple nodes to be aggregated. We develop an automated data management system that significantly reduces communication overheads, enabling new capabilities for QMC codes. Experimental results with QWalk and QMCPACK demonstrate the effectiveness of the data management system. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
167.
Hannah Baars Julien Engel Lucas Mertens Daniela Meister Carsten Bolm 《Advanced Synthesis \u0026amp; Catalysis》2016,358(14):2293-2299
Carbamoyl fluorides are formed in reactions of hydroxylamines with difluorocarbene generated from sodium bromodifluoroacetate as readily available and non‐toxic carbene precursor. The process shows a high functional group tolerance, and the reaction path has been rationalized by computational calculations.
168.
In the last few years, thermal comfort research in summer has significantly increased the electricity consumption in buildings. This is mainly due to the use of conventional air conditioning systems operating with mechanical vapor compression. Solar cooling systems appear to be an interesting solution to solve this problem. But the understanding of this technology has to be refined through fundamental studies by developing numerical simulations. Moreover, the study of pilot plants is a practical method to gain experience by analyzing all the processes behind solar cooling technology. This paper presents an experimental study of a solar cooling absorption system implemented in Reunion Island, located in the southern hemisphere near the Capricorn Tropic. The particularity of this project is to achieve an effective cooling of classrooms, by a solar cooling system without any backup systems (hot or cold). The aim of this experimental study is to define the limits of the use of such system under tropical climate conditions without setting a set point temperature. Indoor thermal comfort is achieved by a self-stabilizing operating system that maintains the indoor temperature 6 °C below the outdoor temperature. During some critical periods of the year, when the outdoor temperature is very high and when the solar cooling system cannot provide enough refrigerating production, thermal comfort inside the building is achieved by using ceiling fans. Firstly we will present the installation and the choices we made in the control and design process. In the second part, an analysis of the experimental results will be presented. 相似文献
169.
Righi AA Alves TR Negri G Marques LM Breyer H Salatino A 《Journal of the science of food and agriculture》2011,91(13):2363-2370
BACKGROUND: Chloroform, ethyl acetate and methanol extracts of a sample of red propolis from the state of Alagoas (northeast Brazil) were analyzed by gas chromatography–mass spectrometry and high‐performance liquid chromatography–diode array detection–electrospray ionization‐mass spectrometry. Antimicrobial and antioxidant activities were also obtained. RESULTS: The propolis sample contained low content of narigenin‐8‐C‐hexoside, this being the first report of a C‐glycoside in propolis. The main constituent found was characterized as 3,4,2′,3′‐tetrahydroxychalcone. Other important constituents were the chalcone isoliquiritigenin, the isoflavans (3S)‐vestitol, (3S)‐7‐O‐methylvestitol, the pterocarpan medicarpin, the phenylpropenes trans‐anethol, methyl eugenol, elimicin, methoxyeugenol and cis‐asarone, and the triterpenic alcohols lupeol and α‐ and β‐ amyrins. The methanol extract exhibited high antioxidant activities by 2,2‐diphenyl‐1‐picrylhydrazyl and β‐carotene/linoleic acid assay methods, and antimicrobial activity toward Gram‐positive and Gram‐negative bacteria. CONCLUSION: Structures are suggested for new substances never before seen in any kind of propolis. This is the first report of 3,4,2′,3′‐tetrahydroxychalcone and a flavone C‐glycoside in a propolis sample. Copyright © 2011 Society of Chemical Industry 相似文献
170.
Sergio Neves Monteiro Felipe Perissé Duarte Lopes Anderson Paula Barbosa Alice Barreto Bevitori Isabela Leão Amaral Da Silva Lucas Lopes Da Costa 《Metallurgical and Materials Transactions A》2011,42(10):2963-2974
Recent investigations on the tensile properties of natural cellulose-based fibers revealed an increasing potential as engineering
materials. This is particularly the case of very thin fibers of some species such as sisal, ramie, and curaua. However, several
other commonly used fibers such as flax, jute, hemp, coir, cotton, and bamboo as well as less known bagasse, piassava, sponge
gourde, and buriti display tensile properties that could qualify them as engineering materials. An overview of the strength
limits attained by these fibers is presented. Based on a tensile strength vs density chart, it is shown that natural fibers stand out as a relevant class of engineering materials. 相似文献