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排序方式: 共有501条查询结果,搜索用时 31 毫秒
21.
Nicolas Vivas Guy Bourgeois Christiane Vitry Yves Glories Victor de Freitas 《Journal of the science of food and agriculture》1996,72(3):309-317
The composition of various commercial tannin extracts were determined by liquid secondary ion mass spectrometry (LSIMS). Spectra were obtained directly from tannin extracts without any pre-separation. Eight different tannin powders were analysed: three gallotannins (Chinese, Turkish, tara), three ellagitannins (sweet chestnut, pendunculata oak, sessile oak), one mixed hydrolysable tannin (myrabolans) and one proanthocyanidin (grape seeds). This method enabled the main molecules in these powders to be identified. 相似文献
22.
23.
Christiane L. Ojaimi Julieta A. Ferreira Adilson L. Chinelatto Raphael E. P. Salem Adriana S. A. Chinelatto Eliria M. J. A. Pallone 《International Journal of Applied Ceramic Technology》2020,17(4):1619-1628
Composites of Al2O3/ZrO2 (containing 25, 50, and 75 vol% ZrO2) were prepared by mixing Al2O3 and ZrO2 suspensions. The microstructural control via two-step sintering (TSS) was the main objective of this work. For this purpose, different sintering curves were constructed, aiming to achieve the best temperature combination for the sintering steps that provides higher density and finer microstructure. The results were compared with single-step sintering (SSS). Furthermore, microhardness and fracture toughness were measured for the best TSS specimens under each composition. The results showed that the high densities were obtained, and the reduction of grain size was greater than 40% for two-step sintered specimens, compared to SSS ones. Consequently, microhardness values increased. However, fracture toughness values remained unchanged. 相似文献
24.
Mayrhofer S Domig KJ Amtmann E Van Hoek AH Petersson A Mair C Mayer HK Kneifel W 《Journal of food protection》2007,70(1):119-124
The widespread use of antimicrobial substances has led to resistant populations of microorganisms in several ecosystems. In animal husbandry, the application of antibiotics has contributed to resistance development in pathogenic and commensal bacteria. These strains or their resistance genes can be spread along several ecological routes, including the food chain. Antibiotic resistance is important in terms of the safety of industrial strains, such as probiotics for food and feed. Bifidobacterium thermophilum and Bifidobacterium pseudolongum are known to comprise the major part of the bifidobacterial microbiota in the gut and feces of cattle and pigs. In this study, the antimicrobial susceptibility in bifidobacterial isolates of these species was investigated. Isolates from the beef and pork production chain were identified and typed to strain level, and the antimicrobial susceptibility level was tested to a set of antibiotics. Isolates with low susceptibility levels were screened by PCR for already described resistance genes. Strains atypically resistant to clindamycin, erythromycin, and tetracycline were determined. The resistance genes tet(O), tet(W), and erm(X) were detected in the bifidobacterial species that were examined. 相似文献
25.
Patients with peanut allergy are often serologically sensitised to other legumes. If primary peanut allergy was contracted,
secondary allergies to other legume plants may develop. The cross-sensitisation implies an enhanced risk of food-related anaphylaxis
for the patients even if its clinical relevance is under discussion. In the present study, 32 patients with anti-peanut immunoglobulin
E-levels (IgE) of at least class 1 according to the ImmunoCap™ classification system were included. The patients had been
referred to the Norwegian National Register and Reporting System for Severe Allergic Reactions to Food with histories of anaphylaxis
by the consumption of legume-containing foods. The patient sera were analysed for IgE that reacted to peanut (Arachis hypogea), soybean (Glycine max), pea (Pisum sativum), lupin (Lupinus albus) and fenugreek (Trigonella foenum graecum). Immunoblot experiments were performed using extracts of in total eight different legume plants. IgE measurements and blot
analyses revealed differentiated patterns of legume sensitisation. One third of the patients had anti-peanut IgE class 4 to
6. In contrast, just one patient had specific IgE higher than class 4 to respectively pea, soybean and fenugreek. However,
ten patients had elevated anti-fenugreek IgE (≥class 3), significantly more than for the other legumes. The second highest
levels were found for soybean, followed by pea and lupin. The immunoblots showed particularly strong IgE binding to proteins
at 12, 22, 30, 36 and 50 kDa for all legumes, indicating that the major peanut allergens Ara h 1, Ara h 2 and Ara h 3 are
strong candidates for causing cross-sensitivity. 相似文献
26.
Mario Cano-Muoz Julie Lucas Li-Yun Lin Samuele Cesaro Christiane Moog Francisco Conejero-Lara 《International journal of molecular sciences》2022,23(5)
Inhibition of the HIV-1 fusion process constitutes a promising strategy to neutralize the virus at an early stage before it enters the cell. In this process, the envelope glycoprotein (Env) plays a central role by promoting membrane fusion. We previously identified a vulnerability at the flexible C-terminal end of the gp41 C-terminal heptad repeat (CHR) region to inhibition by a single-chain miniprotein (named covNHR-N) that mimics the first half of the gp41 N-terminal heptad repeat (NHR). The miniprotein exhibited low stability, moderate binding to its complementary CHR region, both as an isolated peptide and in native trimeric Envs, and low inhibitory activity against a panel of pseudoviruses. The addition of a disulfide bond stabilizing the miniprotein increased its inhibitory activity, without altering the binding affinity. Here, to further study the effect of conformational stability on binding and inhibitory potency, we additionally stabilized these miniproteins by engineering a second disulfide bond stapling their N-terminal end, The new disulfide-bond strongly stabilizes the protein, increases binding affinity for the CHR target and strongly improves inhibitory activity against several HIV-1 strains. Moreover, high inhibitory activity could be achieved without targeting the preserved hydrophobic pocket motif of gp41. These results may have implications in the discovery of new strategies to inhibit HIV targeting the gp41 CHR region. 相似文献
27.
Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase‐treated broccoli sprout extract 下载免费PDF全文
28.
The impact of dietary fibers on dendritic cell responses in vitro is dependent on the differential effects of the fibers on intestinal epithelial cells 下载免费PDF全文
29.
Chaudhury Dipesh; Manella Laura; Arellanos Adolfo; Escanilla Olga; Cleland Thomas A.; Linster Christiane 《Canadian Metallurgical Quarterly》2010,124(4):490
Habituation is a simple form of memory, yet its neurobiological mechanisms are only beginning to be understood in mammals. In the olfactory system, the neural correlates of habituation at a fast experimental timescale involving very short intertrial intervals (tens of seconds) have been shown to depend on synaptic adaptation in olfactory cortex. In contrast, behavioral habituation to odorants on a longer timescale with intertrial intervals of several minutes depends on processes in the olfactory bulb, as demonstrated by pharmacological studies. We here show that behavioral habituation to odorants on this longer timescale has a neuronal activity correlate in the olfactory bulb. Spiking responses of mitral cells in the rat olfactory bulb adapt to, and recover from, repeated odorant stimulation with 5-min intertrial intervals with a time course similar to that of behavioral habituation. Moreover, both the behavioral and neuronal effects of odor habituation require functioning N-methyl-d-aspartic acid receptors in the olfactory bulb. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
30.