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201.
Andreas Ruh Adam-Mwanga Dieckmann Richard Heldele Volker Piotter Robert Ruprecht Christian Munzinger Jürgen Fleischer Jürgen Haußelt 《Microsystem Technologies》2008,14(12):1805-1811
In the field of micro-technology the production of metallic and ceramic micro-components by powder injection molding (PIM)
has become a more and more established fabrication method. But in order to fulfill the demand for more complex-shaped high-precision
micro-components further development work has to be performed. This is especially true if more efficient production routes
for multi-component-micro-assemblies consisting of different materials or sub-components are envisaged. To meet these challenges,
investigations are performed to realize and to establish two primary shape micro-processes. These are two-component micro-injection
molding (2C-MicroPIM) and sinter-joining. The realization of these technologies will lead to a markedly reduction of the efforts
for handling, adjustment, and assembling of metallic and ceramic micro-assemblies. Furthermore, an increased integration level
and functionality can be yielded. For an effective transfer of scientific results to industrial applications the whole process
chain must be considered, from development and construction of the tooling as well as of the components to the quality assurance
and determination of the properties of the assemblies after sintering. These primary shape processes shall enable the mutual
processing of different materials within the fabrication process, so avoiding separate mounting or assembling steps. Additionally
fixed and loose junctions between at least two components shall be realized. The progress in research and development will
be demonstrated especially by the implementation of shaft-to-collar connections between micro-gearwheels and corresponding
shafts. Regarding two-component micro-injection molding, the tool construction for shaft-to-collar connections will be presented
as well as first experimental results on the properties of selected ceramic powders and feedstocks for the special requirements
of the 2C-MicroPIM process. With the assembly step being performed outside the injection molding tool before sinter-joining
different parts and geometries can be combined quite easily. The presented article gives an overview on the concept and on
preliminary testing results for the fabrication of a shaft-to-collar-connection. Additionally, a solution for an automated
assembly of a shaft and a toothed wheel outside the injection molding tool is presented. 相似文献
202.
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205.
Nils Paust Christian Litterst Tobias Metz Michael Eck Christoph Ziegler Roland Zengerle Peter Koltay 《Microfluidics and nanofluidics》2009,7(4):531-543
In this paper we present a new concept of creating and using capillary pressure gradients for passive degassing and passive methanol supply in direct methanol fuel cells (DMFCs). An anode flow field consisting of parallel tapered channels structures is applied to achieve the passive supply mechanism. The flow is propelled by the surface forces of deformed CO2 bubbles, generated as a reaction product during DMFC operation. This work focuses on studying the influence of channel geometry and surface properties on the capillary-induced liquid flow rates at various bubbly gas flow rates. Besides the aspect ratios and opening angles of the tapered channels, the static contact angle as well as the effect of contact angle hysteresis has been identified to significantly influence the liquid flow rates induced by capillary forces at the bubble menisci. Applying the novel concept, we show that the liquid flow rates are up to thirteen times higher than the methanol oxidation reaction on the anode requires. Experimental results are presented that demonstrate the continuous passive operation of a DMFC for more than 15 h. 相似文献
206.
Sunil Kumar Richard J. Pippy Erdem Acar Nam H. Kim Raphael T. Haftka 《Structural and Multidisciplinary Optimization》2009,38(6):613-626
Probabilistic structural design deals with uncertainties in response (e.g. stresses) and capacity (e.g. failure stresses).
The calculation of the structural response is typically expensive (e.g., finite element simulations), while the capacity is
usually available from tests. Furthermore, the random variables that influence response and capacity are often disjoint. In
previous work we have shown that this disjoint property can be used to reduce the cost of obtaining the probability of failure
via Monte Carlo simulations. In this paper we propose to use this property for an approximate probabilistic optimization based
on exact capacity and approximate response distributions (ECARD). In Approximate Probabilistic Optimization Using ECARD, the
change in response distribution is approximated as the structure is re-designed while the capacity distribution is kept exact,
thus significantly reducing the number of expensive response simulations. ECARD may be viewed as an extension of SORA (Sequential
Optimization and Reliability Assessment), which proceeds with deterministic optimization iterations. In contrast, ECARD has
probabilistic optimization iterations, but in each iteration, the response distribution is approximated so as not to require
additional response calculations. The use of inexpensive probabilistic optimization allows easy incorporation of system reliability
constraints and optimal allocation of risk between failure modes. The method is demonstrated using a beam problem and a ten-bar
truss problem. The former allocates risk between two different failure modes, while the latter allocates risk between members.
It is shown that ECARD provides most of the improvement from risk re-allocation that can be obtained from full probabilistic
optimization. 相似文献
207.
Christoph Riedl Tilo Böhmann Michael Rosemann Helmut Krcmar 《Information Systems and E-Business Management》2009,7(2):199-221
Service-oriented architectures and Web services mature and have become more widely accepted and used by industry. This growing
adoption increased the demands for new ways of using Web service technology. Users start re-combining and mediating other
providers’ services in ways that have not been anticipated by their original provider. Within organisations and cross-organisational
communities, discoverable services are organised in repositories providing convenient access to adaptable end-to-end business
processes. This idea is captured in the term Service Ecosystem. This paper addresses the question of how quality management
can be performed in such service ecosystems. Service quality management is a key challenge when services are composed of a
dynamic set of heterogeneous sub-services from different service providers. This paper contributes to this important area
by developing a reference model of quality management in service ecosystems. We illustrate the application of the reference
model in an exploratory case study. With this case study, we show how the reference model helps to derive requirements for
the implementation and support of quality management in an exemplary service ecosystem in public administration. 相似文献
208.
Jastorff AM Haegler K Maccarrone G Holsboer F Weber F Ziemssen T Turck CW 《Proteomics. Clinical applications》2009,3(11):1273-1287
Multiple sclerosis is characterized by inflammatory demyelination and axonal loss as pathophysiological correlates of relapsing activity and progressive development of clinical disability. The molecular processes involved in this pathogenesis are still unclear as they are quite complex and heterogeneous. In this article we present protein expression analysis of brain and spinal cord tissues from different models of murine experimental autoimmune encephalomyelitis (EAE), the most commonly used animal model for multiple sclerosis. We observed a number of EAE-specific protein expression and PTM differences. Proteome analysis was extended to multiple sclerosis specimens in order to validate the EAE findings. Our findings suggest the regulation of a number of proteins that shed light on the molecular mechanisms of the disease processes taking place in EAE and multiple sclerosis. We found consistent modulation of proteins including serum amyloid P component, sirtuin 2, dihydropyrimidinase-related protein family proteins, stathmin 1, creatine kinase B and chloride intracellular channel protein 1. Functional classification of the proteins by database and the literature mining reveals their association with neuronal development and myelinogenesis, suggesting possible disease processes that mediate neurodegeneration. 相似文献
209.
With the proliferation of macroergonomic field research, it is time to carefully examine how such research should be managed and implemented. We argue that the importance of attending to high-quality implementation of field research is equal to that of methodological rigor. One way to systematically manage the implementation process is to adopt a change management framework, wherein the research project is conceptualized as an instance of organization-level change. Consequently, principles for successful organization-level change from the literature on change management can be used to guide successful field research implementation. This paper briefly reviews that literature, deriving 30 principles of successful change management, covering topics such as political awareness, assembling the change team, generating buy-in, and management support. For each principle, corresponding suggestions for macroergonomic field research practice are presented. We urge other researchers to further develop and adopt frameworks that guide the implementation of field research. 相似文献
210.
The main part of the code presented in this work represents an implementation of the split-operator method [J.A. Fleck, J.R. Morris, M.D. Feit, Appl. Phys. 10 (1976) 129-160; R. Heather, Comput. Phys. Comm. 63 (1991) 446] for calculating the time-evolution of Dirac wave functions. It allows to study the dynamics of electronic Dirac wave packets under the influence of any number of laser pulses and its interaction with any number of charged ion potentials. The initial wave function can be either a free Gaussian wave packet or an arbitrary discretized spinor function that is loaded from a file provided by the user. The latter option includes Dirac bound state wave functions. The code itself contains the necessary tools for constructing such wave functions for a single-electron ion. With the help of self-adaptive numerical grids, we are able to study the electron dynamics for various problems in 2+1 dimensions at high spatial and temporal resolutions that are otherwise unachievable.Along with the position and momentum space probability density distributions, various physical observables, such as the expectation values of position and momentum, can be recorded in a time-dependent way. The electromagnetic spectrum that is emitted by the evolving particle can also be calculated with this code. Finally, for planning and comparison purposes, both the time-evolution and the emission spectrum can also be treated in an entirely classical relativistic way.Besides the implementation of the above-mentioned algorithms, the program also contains a large C++ class library to model the geometric algebra representation of spinors that we use for representing the Dirac wave function. This is why the code is called “Dirac++”.
Program summary
Program title: Dirac++ or (abbreviated) d++Catalogue identifier: AEAS_v1_0Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEAS_v1_0.htmlProgram obtainable from: CPC Program Library, Queen's University, Belfast, N. IrelandLicensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.htmlNo. of lines in distributed program, including test data, etc.: 474 937No. of bytes in distributed program, including test data, etc.: 4 128 347Distribution format: tar.gzProgramming language: C++Computer: Any, but SMP systems are preferredOperating system: Linux and MacOS X are actively supported by the current version. Earlier versions were also tested successfully on IRIX and AIXNumber of processors used: Generally unlimited, but best scaling with 2-4 processors for typical problemsRAM: 160 Megabytes minimum for the examples given hereClassification: 2.7External routines: FFTW Library [3,4], Gnu Scientific Library [5], bzip2, bunzip2Nature of problem: The relativistic time evolution of wave functions according to the Dirac equation is a challenging numerical task. Especially for an electron in the presence of high intensity laser beams and/or highly charged ions, this type of problem is of considerable interest to atomic physicists.Solution method: The code employs the split-operator method [1,2], combined with fast Fourier transforms (FFT) for calculating any occurring spatial derivatives, to solve the given problem. An autocorrelation spectral method [6] is provided to generate a bound state for use as the initial wave function of further dynamical studies.Restrictions: The code in its current form is restricted to problems in two spatial dimensions. Otherwise it is only limited by CPU time and memory that one can afford to spend on a particular problem.Unusual features: The code features dynamically adapting position and momentum space grids to keep execution time and memory requirements as small as possible. It employs an object-oriented approach, and it relies on a Clifford algebra class library to represent the mathematical objects of the Dirac formalism which we employ. Besides that it includes a feature (typically called “checkpointing”) which allows the resumption of an interrupted calculation.Additional comments: Along with the program's source code, we provide several sample configuration files, a pre-calculated bound state wave function, and template files for the analysis of the results with both MatLab and Igor Pro.Running time: Running time ranges from a few minutes for simple tests up to several days, even weeks for real-world physical problems that require very large grids or very small time steps.References:- [1]
- J.A. Fleck, J.R. Morris, M.D. Feit, Time-dependent propagation of high energy laser beams through the atmosphere, Appl. Phys. 10 (1976) 129-160.
- [2]
- R. Heather, An asymptotic wavefunction splitting procedure for propagating spatially extended wavefunctions: Application to intense field photodissociation of H+2, Comput. Phys. Comm. 63 (1991) 446.
- [3]
- M. Frigo, S.G. Johnson, FFTW: An adaptive software architecture for the FFT, in: Proceedings of the IEEE International Conference on Acoustics, Speech and Signal Processing, vol. 3, IEEE, 1998, pp. 1381-1384.
- [4]
- M. Frigo, S.G. Johnson, The design and implementation of FFTW3, in: Proceedings of the IEEE, vol. 93, IEEE, 2005, pp. 216-231. URL: http://www.fftw.org/.
- [5]
- M. Galassi, J. Davies, J. Theiler, B. Gough, G. Jungman, M. Booth, F. Rossi, GNU Scientific Library Reference Manual, second ed., Network Theory Limited, 2006. URL: http://www.gnu.org/software/gsl/.
- [6]
- M.D. Feit, J.A. Fleck, A. Steiger, Solution of the Schrödinger equation by a spectral method, J. Comput. Phys. 47 (1982) 412-433.