The effect of carotid sinus denervation on fetal heart rate variation in normoxia, hypoxia and post-hypoxia in fetal sheep

BACKGROUND: Previous reports documented high rates of tobacco use among Alaska Natives (Eskimos, Indians, and Aleuts). In this population, tobacco use is the leading preventable cause of death. Lung cancer is the leading cause of cancer death among Alaska Natives and tobacco is responsible for over one-third of all cancer deaths in this population. Until recently there has been no systematic surveillance of the prevalence of tobacco use in this high-risk population. Data that did exist were not readily available to those primarily responsible for the health care of this population. This is the first time since 1990 that data on Alaska Natives have been collected in one analysis; this permits a more representative evaluation of tobacco use. METHODS: Data on tobacco use were obtained and analyzed from national and state surveys and selected research projects from 1988 to 1993. RESULTS: Alaska Natives have high prevalence of tobacco use, including both cigarettes and smokeless tobacco. Tobacco use prevalence among Alaska Natives exceeds that of Alaska non-Natives, U.S. whites, and American Indians/Alaska Natives in the United States outside of Alaska. Smoking prevalence among Alaska Native women is twice that of non-Native women in Alaska and nearly twice as high among pregnant Alaska Natives than pregnant non-Natives. Overall, prevalence of smokeless tobacco use was four times higher among Alaska Natives than comparative state and national populations. CONCLUSION: Because this population has such high rates of tobacco use, it is important to public health that monitoring and educational programs be in place and that data specific to Alaska Natives be made available.     

Structural behaviour of a dry dock with pile-anchored bottom slab

In this article the analysis and theoretical interpretation of the results obtained in the observation of some cross sections of dock 21 of SETENAVE shipyards is described. The deformability of a large construction, whose behaviour showed marked interaction with the surrounding soil was studied. The overall behaviour is strongly affected by the behaviour of a vast zone of piles, densely distributed and subjected to strong tensile and compressive forces. The purpose of theoretical treatment of results obtained directly from the prototype, which are still quite rare, was to improve the knowledge needed for the design of this kind of structures. The interpretation of the results also provided a better knowledge of the behaviour of large groups of piles subjected to tensile forces, which are very difficult to study in the laboratory. The type of problem dealt with is not limited to dry docks anchored on piles. It also concerns other types of structures, either sunk or at earthfill level, such as large resevoirs, nuclear plants, etc.     

Predicting porosity content in triaxial porcelain bodies as a function of raw materials contents

This work describes the relationships observed between the porosity of fired ceramic test pieces and the raw materials contents in the unfired mixture. The investigation was carried out using the mixture experiments design approach coupled with response surface methodology, which enables the calculation of statistically significant models for the properties from a limited number of experimental results. Ten formulations of a clay mixture, potash feldspar and quartz sand were processed in the laboratory under fixed conditions, similar to those used on wall and floor tile industrial practice, and characterized. Closed porosity (CP) was estimated from the analysis of back-scattered SEM photomicrographs, open porosity (OP) was calculated as the product of bulk density and water absorption, and total porosity (TP) was calculated from OP and CP values. Characterization results were used to calculate statistically significant and valid regression equations, relating those properties with the raw material contents in the unfired mixture. For the particular raw materials and processing conditions used, the models clearly show how quartz contributes to increasing OP and the crucial role played by feldspar when CP and TP are to be minimized (circa 3 vol.%), and how the clay content can counteract that effect and lead to maximum closed porosity (∼14 vol.%).     

Signal probability for reliability evaluation of logic circuits

As integrated circuits scale down into nanometer dimensions, a great reduction on the reliability of combinational blocks is expected. This way, the susceptibility of circuits to intermittent and transient faults is becoming a key parameter in the evaluation of logic circuits, and fast and accurate ways of reliability analysis must be developed. This paper presents a reliability analysis methodology based on signal probability, which is of straightforward application and can be easily integrated in the design flow. The proposed methodology computes circuit’s signal reliability as a function of its logical masking capabilities, concerning multiple simultaneous faults occurrence.     

Simple High Performance General Purpose Single Channel Analyser

A simple single channel analyser using standard components is described. High temperature stability (0.002% / °C) and resolution (? 100 ?V) is achieved. The two-level generator circuits described allow full DC coupling of the input pulses. The performance of these circuits is discussed in detail and experimental results presented.     

Janus particle amphiphilicity and capillary interactions at a fluid interface

Studying the behavior of anisotropic particles at fluid interfaces is a rapidly expanding field, as understanding how the introduced anisotropy affects the resulting properties is essential in the engineering of interfacial systems. Surface anisotropic particles, also known as Janus particles (JPs), offer new possibilities for novel applications due to their amphiphilicity and stronger binding to fluid interfaces compared to homogeneous particles. Introducing surface anisotropy creates complexity as the orientation of interfacially bound particles affects interparticle interactions, a contributing factor to the microstructure formation. In this work, we have investigated the microstructure of JP monolayers formed at the air–water interface using particles with different degrees of amphiphilicity and examined the response of the networks to applied compressions. Our findings demonstrate that JPs amphiphilicity is a crucial factor governing their orientation at the interface, which in turn dictates the complexity of the capillary interactions present and the mechanical properties of the ensuing networks.     

A brief abstinence test for college student smokers: A feasibility study.

Cigarette smoking among college students is prevalent and correlated with other unhealthy behaviors. Reinforced abstinence (e.g., contingency management) has been demonstrated to be an effective method for reducing substance use in a variety of populations and across a variety of drugs, including cigarettes. Reinforced abstinence has seldom been used specifically targeting a college student population. A Brief Abstinence Test (BAT) has been used to effectively reduce cocaine use among methadone maintenance patients (Robles, Silverman, Preston, Cone, Katz, Bigelow, & Stitzer, 2000). However, no published studies have investigated the use of a BAT to reduce the use of cigarettes. The current study implemented a 3-week intervention (Baseline 1, BAT, and Baseline 2 weeks) for smoking abstinence among college students. Forty-two percent of the sample met abstention criteria during the BAT. Carbon monoxide and urinalysis scores decreased significantly from Baseline 1 to the BAT phase but did not differ significantly from BAT to Baseline 2. These results suggest that the BAT may have utility initiating abstinence in both clinical and research contexts. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

First-order,buckling and post-buckling behaviour of GFRP pultruded beams. Part 2: Numerical simulation

This work deals with the numerical evaluation of the structural response of simply supported (transversally loaded at mid-span) and cantilever (subjected to tip point loads) beams built from a commercial pultruded I-section GFRP profile. In particular, the paper addresses the beam (i) geometrically linear behaviour in service conditions, (ii) local and lateral-torsional buckling behaviour, and (iii) lateral-torsional post-buckling behaviour, including the effect of the load point of application location. The numerical results are obtained by means of (i) novel Generalised Beam Theory (GBT) beam finite element formulations, able to capture the influence of the load point of application, and (ii) shell finite element analyses carried out in the code Abaqus. These numerical results are compared with (i) the experimental values reported and discussed in the companion paper (Part 1) and (ii) values provided by analytical formulae available in the literature.     

Creep behavior of pultruded GFRP elements – Part 2: Analytical study

This paper presents an analytical study about the viscoelastic time-dependent (creep) behavior of pultruded GFRP elements made of polyester and E-glass fibers. Experimental results reported in Part 1 are firstly used for material characterization by means of empirical and phenomenological formulations – a good general agreement is obtained using the following analytical models: (i) Findley’s power law, (ii) Bruger–Kelvin model and (iii) Prony–Dirichlet series. Based on accelerated characterization methodology – Time-Stress Superposition Principle (TSSP) coupled with Findley’s law, for a reference stress of 20% of the material ultimate stress, an elastic deformation increase of 30% is obtained after 50,000 h. The creep parameters and deformation estimated by using the Findley’s model derivations indicate a consistent prediction of time-dependent deformation and viscoelastic properties of the two types of elements analysed – laminates and beam. A straightforward formulation to predict the time-dependent elastic modulus is applied, showing that the flexural stiffness should be reduced by 25% of its initial value after 1-year and as much as 50% after 50-years. Similarly, the power law coupled to Euler’s classical beam theory suggests a reasonable adaptability to the creep phenomenon in the linear regime and proved to provide accurate predictions for deflections under flexural loading up to 40% of the ultimate strength. After 50 years, under normal service load level (1/3 of the failure load), the total creep deflection will attain almost twice the initial deflection. If taking into account the shear deformation (Timoshenko’s postulated) of the full-size element with “effective” stiffness properties such estimate is reduced nearly 25%.