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101.
Involuntary migration triggered by war has the capacity to generate substantial socioeconomic and environmental changes in cities of developing countries, resulting in aberrant alterations to land use and land cover (LULC). This scenario has the potential to diminish the quality of life of inhabitants of a city and present administrative challenges for government and other officials. Gauging the scope and trajectory of urban LULC changes in a war-related environment is pivotal for urban and regional planning, the sustainability of natural resources, and information needs of policy makers. Scholarships that link remote sensing to social science mostly focus on a non-conflict environment, resulting in little or no information on the ramifications of conflict-induced forced migration on changes in LULC. As a result, the role of civil conflict-induced forced migration on the composition and configuration of urban landscape in developing countries remains elusive. This study employs a dense time stack of Landsat-5 Thematic Mapper (TM) images and a hybrid classification approach that integrates linear spectral unmixing and an ensemble decision-tree classifier to characterize LULC in a primate city and two lower-ranked cities in Sierra Leone. The study examined three time-steps which span 1986–1991, 1991–2002, and 2002–2010 with the overarching goal of elucidating changes in LULC conditioned by civil conflict. Image classification accuracy (overall accuracy) ranged between 84.0% and 90.2%. The study demonstrated that civil conflict has the capacity to trigger notable growth in urban agricultural land (37.4%) in a primate city, while the expansion of residential (112.7%) and industrial/commercial (18.7%) lands is more prominent in a lower-ranked city. The study further revealed that population expansion does not necessarily result in significant growth in residential area in a primate city that has experienced civil conflict.  相似文献   
102.
We introduce Boundary‐Aware Extinction Maps for interactive rendering of massive heterogeneous volumetric datasets. Our approach is based on the projection of the extinction along light rays into a boundary‐aware function space, focusing on the most relevant sections of the light paths. This technique also provides an alternative representation of the set of participating media, allowing scattering simulation methods to be applied on arbitrary volume representations. Combined with a simple out‐of‐core rendering framework, Boundary‐Aware Extinction Maps are valuable tools for interactive applications as well as production previsualization and rendering.  相似文献   
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Integral ESR and time-resolved CIDEP techniques applied to the study of the light-induced yellowing of bleached and unbleached TMP samples provide some further insights into the nature and the mechanisms of the processes. The identity of the phenoxy and ketyl free radical intermediates involved in mese processes is established and the primary triplet photochemical mechanisms of their formation are characterized. The radical scavenging mechanisms responsible for the inhibition of light-induced yellowing in the TMP system by ascorbic acid and triphenylmethyl thiol are formulated.  相似文献   
105.
While nephrologists wait for the ideal, non invasive, inexpensive, precise, and reproducible tool to evaluate extracellular volume (ECV), they need to exert their clinical acumen in the quest of that holy grail, dry weight (DW). Estimation of DW using a clinical approach based on blood pressure (BP) and ECV is feasible and reliable as shown by successful experiences in various dialysis modes over more than three decades. But a need still exists to resolve difficulties associated with accurate assessment of BP (methods and circumstances of measurement, and the confounding effects of antihypertensive drugs) and ECV (evaluation of weight changes unrelated to ECV, lack of specificity and sensitivity of clinical symptoms, lag time, confusion in terminology). An essential point in clinical assessment of DW is that a normal BP is at the same time the target and the crucial index of DW achievement. For this reason, a trialand‐error “probe” process has to be used at intervals to make sure that the dry weight target point is correctly estimated. The various “non clinical” methods proposed for dry weight assessment increase the complexity and the cost of hemodialysis. They are, in the present state of things, more clinical research than practice tools. They do not replace clinical judgment.  相似文献   
106.
Two soybean cDNA clones, SPK-3 and SPK-4, encoding putative protein kinases were isolated and characterized. Both cDNAs encoded approximately 40-kDa serine/threonine kinases with unusual stretches of acidic amino acids in their carboxy-terminal regions, which are highly homologous to PKABA1 from wheat and ASKs from Arabidopsis. These kinases are encoded by one- or two-copy genes in the soybean genome. Notably, SPK-3 and -4 showed different patterns of expression in various soybean tissues. SPK-3 is highly expressed in dividing and elongating tissues of young seedlings but relatively weakly in tissues of mature plants. In contrast, SPK-4 showed relatively high and constitutive expression in all the tissues examined except for leaf tissues of mature plants. Although various stressors, such as dehydration and high salinity, increased the expression of both genes, the induction kinetics were different. The two genes also differed in their response to abscisic acid (ABA). SPK-3 was induced but SPK-4 was not affected by exogenously supplied abscisic acid. In accordance with these expression data analysis of the activity of a chimeric SPK-3 promoter::beta-glucuronidase (GUS) reporter gene by transient expression in tobacco leaves confirmed the inducibility of SPK-3 by salt and ABA. Polyclonal antibodies raised against a recombinant SPK-4 protein produced in Escherichia coli specifically recognized both recombinant SPK-3 and -4 proteins. Kinase assays using affinity-purified SPK-4/ antibody complexes with crude soybean extracts as substrate identified specific phosphorylation of two 41 and 170 kDa soybean proteins that were phosphorylated on serine residues. Taken together, our results suggest that SPK-3, and/or SPK-4 are functional serine protein kinase(s). Furthermore, SPK-3 and -4 may play different roles in the transduction of various environmental stresses.  相似文献   
107.
108.
The prevalence and severity of gingival overgrowth in organ-transplant patients medicated with cyclosporin are greater in patients concomitantly medicated with nifedipine; however, no relationship between the gingival overgrowth and any of the nifedipine pharmacological variables has been demonstrated. The study examined the effect of five nifedipine pharmacological variables (nifedipine dosage, plasma concentration and gingival crevicular fluid concentration, M1 metabolite plasma concentration and the nifedipine: M1 ratio). The effect of the nifedipine variables on the gingival overgrowth score were examined using univariate and multivariate regression analysis. Adjustment for the effect of other risk factors was made by adding the distribution of each of the nifedipine variables in turn to a stepwise regression model containing previously identified risk factors for this condition. Despite the high levels of nifedipine sequestered in the GCF, only the plasma concentration of nifedipine was identified as a risk factor for the severity of gingival overgrowth in these patients (P = 0.01) once adjusted for other known risk factors (R2 for the model = 55%).  相似文献   
109.
110.
Alcohol consumption by young actively growing rats has been previously demonstrated to decrease cortical and cancellous bone density, to reduce trabecular bone volume, and to inhibit bone growth at the epiphyseal growth plate. This study addresses the action of alcohol on cortical bone growth using histomorphometric techniques and on mechanical properties by three-point bending. Four-week-old, female Sprague-Dawley rats were divided into three groups. Alcohol-treated animals were fed a modified Lieber-DeCarli diet ad libitum containing 35% ethanol-derived calories, whereas the pair-fed animals (weight-matched to ethanol rats) received an isocaloric liquid diet in which maltose-dextrin-substituted calories were supplied by ethanol. Chow animals were fed a standard rat chow ad libitum. Femora were removed for analysis after 2, 4, 6, or 8 weeks on the diets. Cortical bone area, bone formation rates, and mineral apposition rates were reduced in the alcohol-fed animals. Bone stiffness, strength, and energy absorbed to fracture were significantly lower in the alcohol-fed animals. This distinctive alcohol effect was revealed to be caused by lower quality bone tissue as reflected by lower elastic moduli and yield strengths.  相似文献   
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