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71.
Recent studies have revealed microscopic amorphous lamella resulting from inelastic deformation in the ballistic impact of boron carbide ceramic. The possibility that these deformation features are a consequence of adiabatic shear deformation in the impact event is explored. An early theory of adiabatic shear that was limited to the response of rigid-plastic deformation is expanded to include elastic strain energy. The study reveals that elastic strain energy is commonly a small, but not negligible, contribution to impact-induced adiabatic shear in metals. Elastic strain energy is paramount in brittle solids. Relations are developed from the theory to predict the nominal width and spacing of adiabatic shear-bands in brittle solids. Comparisons of the theoretical predictions are consistent with observations of impact-induced deformation features in boron carbide.  相似文献   
72.
Scope: An early reaction in osteoarthritic chondrocytes is hyaluronan overproduction followed by proteoglycan loss and collagen degradation. We recently found that hyaluronan is exported by the ATP‐binding cassette transporter multidrug resistance associated protein 5 (MRP5) in competition with cGMP and that some phosphodiesterase 5 inhibitors also inhibited hyaluronan export. These inhibitors also prevented osteoarthritic reactions in cartilage. In an effort to identify the improved inhibitors directed primarily toward MRP5, we analyzed the flavonoids Methods and results: Prenylflavonoids from hop xanthohumol, isoxanthohumol and 8‐prenylnaringenin inhibited MRP5 export at lower concentrations than phosphodiesterase 5 activity. They were analyzed for their effect on IL‐induced osteoarthritic reactions in bovine chondrocytes. Xanthohumol was the superior compound to inhibit hyaluronan export, as well as proteoglycan and collagen loss. It also prevented the shedding of metalloproteases into the culture medium. It directly inhibited MRP5, because it reduced the export of the MRP5 substrate fluorescein immediately and did not influence the hyaluronan synthase activity. Conclusions: Xanthohumol may be a natural compound to prevent hyaluronan overproduction and subsequent reactions in osteoarthritis.  相似文献   
73.
74.
At CRYPTO 2004, Kurosawa and Desmedt presented a new hybrid encryption scheme that is chosen-ciphertext (CCA2) secure in the standard model. Until now it was unknown if the key encapsulation part of the Kurosawa-Desmedt scheme by itself is still CCA2-secure or not. In this note we answer this question to the negative, namely we present a simple CCA2 attack on the Kurosawa-Desmedt key encapsulation mechanism. Our attack further supports the design paradigm of Kurosawa and Desmedt to build CCA2-secure hybrid encryption from weak key encapsulation.  相似文献   
75.
Previous research on perceiving spatial layout has found that people often exhibit normative biases in their perception of the environment. For instance, slant is typically overestimated and distance is usually underestimated. Surprisingly, however, the perception of height has rarely been studied. The present experiments examined the perception of height when viewed from the top (e.g., looking down) or from the bottom (e.g., looking up). Multiple measures were adapted from previous studies of horizontal extents to assess the perception of height. Across all of the measures, a large, consistent bias was found: Vertical distances were greatly overestimated, especially from the top. Secondary findings suggest that the overestimation of distance and size that occurs when looking down from a high place correlates with reports of trait- and state-level fear of heights, suggesting that height overestimation may be due, in part, to fear. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
76.
In this paper we propose an agitation method based on megasonic acoustic streaming to overcome the limitations in plating rate and uniformity of the metal deposits during the electroplating process. Megasonic agitation at a frequency of 1 MHz allows the reduction of the thickness of the Nernst diffusion layer to less than 600 nm. Two applications that demonstrate the benefits of megasonic acoustic streaming are presented: the formation of uniform ultra-fine pitch flip-chip bumps and the metallisation of high aspect ratio microvias. For the latter application, a multi-physics based numerical simulation is implemented to describe the hydrodynamics introduced by the acoustic waves as they travel inside the deep microvias.  相似文献   
77.
Clinical trials with cocaine-dependent outpatients have found a strong relation between in-treatment and follow-up abstinence, and the strength of this relation is constant across treatment conditions with variable efficacy in generating abstinence. The authors conducted secondary analyses of data from 3 clinical trials to determine whether this relation generalizes to cocaine-dependent homeless persons. The 3 trials (total N = 543) were conducted in a community health care facility for homeless people. The 7 treatment arms across the 3 trials were combinations of day treatment, abstinence-contingent housing, and vocational training. Drug use was measured with urine toxicology testing. Consecutive weeks of abstinence during treatment were strongly related to abstinence at the 12-month follow-up, whether or not missing 12-month data were included in the analysis. The treatment arms differed in their efficacy in generating abstinence, but the relation between in-treatment and follow-up abstinence did not differ across treatment arms. These results replicate earlier reports of these relations and extend them to a population of homeless people. The lack of differences between treatment arms in the in-treatment–follow-up abstinence relation implies that that relation is independent of the treatment-specific intervention components that generate group differences in abstinence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
78.
Previous research has suggested that perceived distances are scaled by the action capabilities of the body. The present studies showed that when “reachability” is constrained due to a difficult grasp required to pick up an object, perceived distance to the object increases. Participants estimated the distances to tools with handle orientations that made them either easy or difficult to grasp with their dominant and nondominant hands. Right-handed participants perceived tools that were more difficult to grasp to be farther away than tools that were easier to grasp. However, perceived distance did not differ in left-handed participants. These studies suggest that, when reaching toward a target, the distance to that target is scaled in terms of how far one can effectively reach, given the type of reaching posture that is executed. Furthermore, this effect is modulated by handedness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
79.
This review draws on knowledge for the treatment of heavy‐metal leachate in contaminated mine sites. Mine waste rock dumps and tailings generate a continuous stream of metalliferous and saline leachate over the long term. The mining industry has many legacy sites, which have compromised aquatic ecosystems and groundwater because of heavy‐metal contamination. Chemical and engineering methods are available and have been extensively utilised. However, these methods require intensive energy and often produce substantial volumes of secondary waste. We therefore argue in favour of phytoremediation as a sustainable remediation strategy leading towards efficient and sustainable metal removal and immobilisation through constructed wetlands.  相似文献   
80.
This paper examines the relationships between construction planning efforts and construction planning effectiveness. The influence of the project's environment and organizational characteristics of construction firms on planning efforts and planning effectiveness is also investigated. A sample of 26 building projects was studied and the results were analysed using simple correlations. Three factors were found to have a significant effect on improving construction planning effectiveness: increases in planning time prior to commencement of work on site, the extent to which emphasis is placed on the determination of construction methods during construction planning and the frequency of revision of construction plans after commencement of work on site. Significant relationships were also found between project environment variables and organizational characteristics of construction firms and planning efforts and planning effectiveness. Implications of the results are that construction planners should systematically evaluate alternative plans, sufficient time should be allowed for proper planning, thorough reviews are needed whilst work is in progress, the planning effort needs to be relevant to the environmental context of the project and the firm should be appropriately organized. Suggestions are given for future research studies.  相似文献   
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