Method detection limit determination and application of a convenient headspace analysis method for methyl tert-butyl ether in water

Methyl tert-butyl ether (MTBE) is a common groundwater contaminant, introduced to the environment by leaking petroleum storage tanks, urban runoff, and motorized watercraft. In this study. a simplified (static) headspace analysis method was adapted for determination of MTBE in water samples and soil water extracts. The MDL of the headspace method was calculated to be 2.0 microg L(-1) by the EPA single-concentration design method(1) and 1.2 microg L(-1) by a calibration method developed by Hubaux and Vos (Hubaux, A.; Vos, G. Anal. Chem. 1970,42, 849-855). The MDL calculated with the Hubaux and Vos method was favored because it considers both a true positive and a false positive. The static headspace method was applied to analysis of a tap water sample and a monitoring well sample from a gasoline service station, a river sample, and aqueous extracts from soil excavated during removal of a leaking underground storage tank (LUST). The water samples examined in this study had MTTBE concentrations ranging from 6 to 19 microg L(-1). Aqueous extracts of a soil sample taken from the LUST site had 8 microg L(-1) MTBE.     

Heterostructure photonic crystals: theory and applications

A hybrid structure combining square and hexagonal photonic crystal lattices is presented. This structure, which we refer to as heterostructure, offers the ability to tailor, optimize, and match the band structure of different lattices. The availability of heterostructures in photonic crystals opens abroad range of possibilities for optical device development. In particular, heterostructure photonic crystals are well suited for the application of optical beam splitting (Y coupler) and combining. Numerical experiments performed by use of the finite-difference time-domain method are shown to illustrate the device implemented in both unistructure and heterostructure lattices.     

Numerical study of near-field writing on a phase-change optical disk

Absorption in the phase-change layer of an optical disk located in the near field of a Fabry-Perot laser diode is studied with a combination of finite-difference time domain (FDTD) analysis and a phenomenological laser model that predicts the operational characteristics of a laser diode. Some numerical simulations are performed and results are presented. In addition, the combined FDTD/laser-simulation model is described briefly.     

Oestrogen's masculine side: mediation of mating in male mice

This review focuses on the role of oestrogen in male sexual behaviour using oestrogen receptor alpha and beta knockout (ERalphaKO and ERbetaKO) mouse models. ERbetaKO mice are capable of mating and producing offspring, whereas ERalphaKO mice are unable to do either. When ERalphaKO males are treated with testosterone or dihydrotestosterone (DHT), < 50% display mounting behaviour, few intromit and none ejaculate. However, concurrent treatment with testosterone and a dopamine agonist instates masculine sexual behaviour in both male and female ERalphaKO mice. Dopamine content in the preoptic area and associated regions is not affected by oestrogen receptor alpha gene disruption. However, expression of neuronal nitric oxide synthase immunoreactivity is severely reduced in ERalphaKO males compared with wild-type males. These findings, together with studies conducted in aromatase knockout mice, are at odds with the dogma that oestrogen is required during development for expression of male sexual behaviour in adults. However, they do support a role for oestrogens, mediated by oestrogen receptor alpha, in regulation and production of neuronal nitric oxide synthase, which in turn may control dopamine agonist release. As has been shown in male rats, in mice dopamine agonist release is likely to be an essential component of the neural pathway that mediates male sexual behaviour.     

Neural network pruning with Tukey-Kramer multiple comparison procedure

Reducing a neural network's complexity improves the ability of the network to generalize future examples. Like an overfitted regression function, neural networks may miss their target because of the excessive degrees of freedom stored up in unnecessary parameters. Over the past decade, the subject of pruning networks produced nonstatistical algorithms like Skeletonization, Optimal Brain Damage, and Optimal Brain Surgeon as methods to remove connections with the least salience. The method proposed here uses the bootstrap algorithm to estimate the distribution of the model parameter saliences. Statistical multiple comparison procedures are then used to make pruning decisions. We show this method compares well with Optimal Brain Surgeon in terms of ability to prune and the resulting network performance.     

GTO也能变XT 激活RADEON X800GTO显卡隐藏性能

ATI凭借RADEON 9700PRO一举在DirectX 9时代 的显卡市场争夺中获得了压倒性优势,这也让NVIDIA 在随后的一年中吃尽苦头。不过在NVIDIA卧薪尝胆推 出GeForce6系列后,开始改变这一状况。ATI随即推 出的RADEON X800XT PE显卡相对NVIDIA的最高端 产品已无太大优势。为了挽回颜面,同时适应PCI Express潮流,ATI紧接着又推出了RADEON X850XT PE 显卡。尽管缺少Shader Model 3．0的支持,但它凭借 540MHz／1180MHz的惊人频率再次从GeForce6800     

Statistical analysis of water-quality data containing multiple detection limits: S-language software for regression on order statistics

Trace contaminants in water, including metals and organics, often are measured at sufficiently low concentrations to be reported only as values below the instrument detection limit. Interpretation of these “less thans” is complicated when multiple detection limits occur. Statistical methods for multiply censored, or multiple-detection limit, datasets have been developed for medical and industrial statistics, and can be employed to estimate summary statistics or model the distributions of trace-level environmental data.We describe S-language-based software tools that perform robust linear regression on order statistics (ROS). The ROS method has been evaluated as one of the most reliable procedures for developing summary statistics of multiply censored data. It is applicable to any dataset that has 0 to 80% of its values censored. These tools are a part of a software library, or add-on package, for the R environment for statistical computing. This library can be used to generate ROS models and associated summary statistics, plot modeled distributions, and predict exceedance probabilities of water-quality standards.     

Field Evaluation of Crushed Glass–Dredged Material Blends

Based on the laboratory results reported in a companion paper, three crushed glass–dredged material (CG–DM) blends were prepared and evaluated in the field to explore the feasibility of using CG–DM blends in general, embankment and structural fill applications. A trailer-mounted pugmill successfully prepared 20/80, 50/50, and 80/20 CG–DM blends (dry weight percent CG content reported first) within a tolerance of ±5 dry % by weight of the targeted percentages. Blending criteria were routinely met at pugmill throughputs up to 1,500?m3/day. The constructed 20/80 CG–DM embankment was compacted to a minimum of 90% modified Proctor compaction, whereas the 50/50 and 80/20 CG–DM embankments were constructed to a minimum of 95% modified Proctor compaction. Twenty to 80% CG addition to DM resulted in 1.5–5.5?kN/m3 increases in field dry densities above 100% DM, densities not achievable with other DM stabilization techniques such as Portland cement, fly ash, and/or lime (PC/FA/lime) addition. CG substantially improved the workability of DM allowing construction with conventional equipment and three person crew while achieving very consistent and reproducible results during a timeline of frequent and heavy precipitation events. The 20/80, 50/50, and 80/20 CG–DM embankments were characterized by average cone tip resistances on the order of 1.0, 1.5, and 2.0?MPa, respectively. An environmental evaluation of 100% CG, DM and 50/50 CG–DM blend samples coupled with an economic analysis of a scaled-up commercial application illustrated that the CG–DM blending approach is potentially more cost effective than PC/FA/lime stabilization approaches. These features of CG–DM blending make the process attractive for use in urban and industrial settings.     

Sex-and age-related differences in ceramide dihexosides of primary human brain tumors

Neutral glycolipids (NGL) are promising diagnostic markers of human gliomas, but differences in NGL with age and sex have not been examined. Previous work demonstrated that ceramide dihexosides (CDH) levels in mouse kidney are age- and sex-dependent, probably due to levels of sex hormones. We quantitated CDH in 181 human gliomas and found significant differences with sex and age, particularly menopause and male puberty. This emphasizes the importance of assessing results of studies on glycolipids in disease states with respect to age and sex in order to avoid erroneous conclusions concerning the relationship of glycolipid composition with diagnosis and pathogenesis.