Effects of pigeon pea and plantain starches on the compressional, mechanical, and disintegration properties of paracetamol tablets

A study has been made of the effects of pigeon pea starch obtained from the plant Cajanus cajan (L) Millisp. (family Fabaceae) and plantain starch obtained from the unripe fruit of Musa paradisiaca L. (family Musaceae) on the compressional, mechanical, and disintegration properties of paracetamol tablets in comparison with official corn starch BP. Analysis of compressional properties was done by using density measurements, and the Heckel and Kawakita equations, whereas the mechanical properties of the tablets were evaluated by using tensile strength (T--a measure of bond strength) and brittle fracture index (BFI--a measure of lamination tendency). The ranking for the mean yield pressure, P(y), for the formulations containing the different starches was generally corn < pigeon pea < plantain starch while the ranking for P(k), an inverse measure of the amount of plasticity, was pigeon pea < plantain < corn starch, which indicated that formulations containing corn starch generally exhibited the fastest onset of plastic deformation, whereas those formulations containing pigeon pea starch exhibited the highest amount of plastic deformation during tableting. The tensile strength of the tablets increased with increase in concentration of the starches while the Brittle Fracture Index decreased. The ranking for T was pigeon pea > plantain > corn starch while the ranking for BFI was corn > plantain > pigeon pea starch. The bonding capacity of the formulations was in general agreement with the tensile strength results. The disintegration time (DT) of the formulation increased with concentration of plantain and corn starches but decreased with concentration of pigeon pea starch. The general ranking of DT values was plantain < pigeon pea < corn starch. Notably, formulations containing pigeon pea starch exhibited the highest bond strength and lowest brittleness, suggesting the usefulness of pigeon pea starch in producing strong tablets with minimal lamination tendency. Plantain starch, on the other hand, would be more useful where faster disintegration of tablet is desired. The results show that the starches could be useful in various formulations depending on the intended use of the tablets with the implication that the experimental starches can be developed for commercial purposes.     

Conceptual semantics in a nonhuman primate.

Some animal vocalizations have been described as referential, or semantic, because individuals respond to them as if they designate some object or event. Alternatively, subjects may simply attend to the acoustic features of calls rather than their meanings. Field playback experiments on diana monkeys (Cercopithecus diana diana) tested these hypotheses using the calls of leopards and eagles and the males' alarm calls to these predators. In the experiment, 2 calls were played in sequence, separated by 5 min of silence, such that they were either (a) similar in acoustic and semantic features, (b) similar in semantic features only, or (c) different in both acoustic and semantic features. Subjects readily transferred habituation across acoustic but not semantic features, suggesting that they attended to the calls' underlying meanings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

What's All the Fuss About Fax?

Facsimile (fax) technology is a fast, inexpensive, and efficient method of accurately transmitting information. In addition to these obvious benefits, however, there are more subtle advantages as well. Fax makes time more elastic, allows smaller companies to be more competitive, and fits nicely with today's leaner staffing trends. This column discusses fax technology and its impact on the business of the organization and the IS department.     

BUILDING THE BUSINESS OF THE FUTURE

Traditional management of information technology must undergo rapid and radical change. Some call the discipline's current state of introspection an identity crisis. Others see it as a crisis for the very survival of the profession. Whatever self-examination IS professionals are experiencing, business management knows what it wants from IT: innovative, creative, entrepreneurial professionals who can step up to the risks and successfully manage them. Organizations need IT professionals who can generate results—and at a pace that can significantly leverage the corporation's ability to create value.     

Pre-licensed driving experience and car crash involvement during the learner and restricted,licence stages of graduated driver licensing: Findings from the New Zealand Drivers Study

Objective

The aim of this study was to determine whether pre-licence driving experiences, that is driving before beginning the licensing process, increased or decreased crash risk as a car driver, during the learner or the restricted licence stages of the graduated driver licensing system (GDLS).

Method

Study participants were 15–24 year old members of the New Zealand Drivers Study (NZDS) – a prospective cohort study of newly licensed car drivers. The interview stages of the NZDS are linked to, the three licensing stages of the GDLS: learner, restricted and full. Baseline demographic (age, ethnicity, residential location, deprivation), personality (impulsivity, sensation seeking, aggression) and, behavioural data, (including pre-licensed driving behaviour), were obtained at the learner licence interview. Data on distance driven and crashes that occurred at the learner licence and restricted licence stages, were reported at the restricted and full licence interviews, respectively. Crash data were also obtained from police traffic crash report files and this was combined with the self-reported crash data. The analysis of the learner licence stage crashes, when only supervised driving is allowed, was based on the participants who had passed the restricted licence test and undertaken the NZDS, restricted licence interview (n = 2358). The analysis of the restricted licence stage crashes, when unsupervised driving is first allowed, was based on those who had passed the full licence test and completed the full licence interview (n = 1428).

Results

After controlling for a range of demographic, personality, behavioural variables and distance driven, Poisson regression showed that the only pre-licence driving behaviour that showed a consistent relationship with subsequent crashes was on-road car driving which was associated with an increased risk of being the driver in a car crash during the learner licence period.

Conclusion

This research showed that pre-licensed driving did not reduce crash risk among learner or restricted licensed drivers, and in some cases (such as on-road car driving) may have increased risk. Young people should be discouraged from the illegal behaviour of driving a car on-road before licensing.     

Parental influence on adolescent compliance with graduated driver licensing conditions and crashes as a restricted licensed driver: New Zealand Drivers Study

Aim

To examine the influence of parental knowledge of, and support for graduated driver licensing (GDL) conditions, parental management of adolescent driving and parental driving behaviour on adolescent compliance with GDL conditions and crashes as a restricted licence driver.

Method

This research was part of the New Zealand Drivers Study (NZDS), a prospective cohort study of 3992 newly licensed car drivers. NZDS participants were recruited at the learner licence stage, with follow-up aligned with the GDL stages. At the restricted licence stage 1200 parents of NZDS adolescents, aged 15–17 years at learner licensure, were recruited and completed interviews. 895 of these adolescents progressed to their full licence and completed the full licence interview. These 895 parent–adolescent pairs were the study population in this research. Topics examined included parental knowledge of, and support for GDL conditions, management of adolescent driving (driving rules, adolescent vehicle ownership, delaying licensure), and their own driving behaviours. Outcomes examined were adolescent compliance with GDL restricted licence conditions (night-time and passenger), and crashes as a driver during the restricted licence stage.

Results

After controlling for other variables, factors independently associated with adolescent low compliance with GDL conditions were: low parental knowledge of conditions, parents’ implementing few driving rules, adolescent vehicle ownership, and parent crash involvement. Factors independently associated with adolescents being a crash involved driver were: parents’ actively delaying licensure, adolescent vehicle ownership, and parent crash involvement.

Conclusion

There is increasing recognition of the importance of parental involvement in adolescent driving. The results show that parents are influential in determining adolescent compliance with GDL and risk of crash. Parents can have considerable positive influence on their adolescent's driving through ensuring compliance with the components of GDL, limiting vehicle ownership and by modelling safe driving behaviours.     

The socialization of dominance: Peer group contextual effects on homophobic and dominance attitudes.

Using the framework of social dominance theory, the current investigation tested for the contextual effects of adolescent peer groups on individuals' homophobic and social dominance attitudes. Results from multilevel models indicated that significant differences existed across peer groups on homophobic attitudes. In addition, these differences were accounted for on the basis of the hierarchy-enhancing or -attenuating climate of the group. A group socialization effect on individuals' social dominance attitudes over time was also observed. Furthermore, the social climate of the peer group moderated the stability of individuals' social dominance attitudes. Findings support the need to examine more proximal and informal group affiliations and earlier developmental periods in efforts to build more comprehensive theoretical models explaining when and how prejudiced and dominance attitudes are formed and the way in which they are perpetuated. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social influences on the acquisition of tool-using behaviors in tufted capuchin monkeys (Cebus apella).

To identify behaviors related to acquisition of tool-use in tufted capuchins (Cebus apella), we presented two tool-using tasks to two groups, extending findings by Westergaard and Fragaszy (1987) and Visalberghi (in press). Five Ss learned to use the tools in each task. The primary predictor of success was level of interest in the task. Observation of others at the apparatus did not facilitate exploratory behaviors or contact with the tools in the observers. Most animals performed exploratory behaviors more often when they were at the apparatus alone than when with another, whether or not the other was using a tool. Observers were quick to learn the relationship between another's activities and the appearance of food. We conclude that capuchins do not readily learn about instrumental relations by observation of others or imitate other's acts. Imitation probably plays no role in the spread of novel instrumental behaviors among monkeys. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Encrypting the global information infrastructure

Information. Global conncetivity. Electronic commerce. Competition. Economic espionage. Global organized crime. Chemical, biological, and nuclear weapons. Terrorism. Conflict. Economic and social instability. Violations of privacy and human rights. Erosion of trust. These are some of the global realities we live with today. They explain why cryptography must be an integral part of the Global Information Infrastructure to protect privacy, intellectual property, and financial assets, and to provide a foundation of trust for electronic commerce. They also explain why we ought to proceed thoughtfully in the deployment of this technology.