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241.
Lara Caetano Rocha Gabriela Klein Barbosa Jurandyr Pimentel Neto Carolina dos Santos Jacob Andreas B. Knudsen Ii-Sei Watanabe Adriano Polican Ciena 《International journal of molecular sciences》2021,22(13)
The myotendinous junction (MTJ) is the muscle-tendon interface and constitutes an integrated mechanical unit to force transmission. Joint immobilization promotes muscle atrophy via disuse, while physical exercise can be used as an adaptative stimulus. In this study, we aimed to investigate the components of the MTJ and their adaptations and the associated elements triggered with aquatic training after joint immobilization. Forty-four male Wistar rats were divided into sedentary (SD), aquatic training (AT), immobilization (IM), and immobilization/aquatic training (IMAT) groups. The samples were processed to measure fiber area, nuclear fractal dimension, MTJ nuclear density, identification of telocytes, sarcomeres, and MTJ perimeter length. In the AT group, the maintenance of ultrastructure and elements in the MTJ region were observed; the IM group presented muscle atrophy effects with reduced MTJ perimeter; the IMAT group demonstrated that aquatic training after joint immobilization promotes benefits in the muscle fiber area and fractal dimension, in the MTJ region shows longer sarcomeres and MTJ perimeter. We identified the presence of telocytes in the MTJ region in all experimental groups. We concluded that aquatic training is an effective rehabilitation method after joint immobilization due to reduced muscle atrophy and regeneration effects on MTJ in rats. 相似文献
242.
Although several studies have examined the effectiveness of local alcohol sales policies on reducing the incidence of driving under the influence (DUI), less is known about whether characteristics of DUI offenders convicted in alcohol-restricted areas differ from those convicted in areas where alcohol is more readily available. A total of 21,647 DUI assessment records were divided into four groups based on the alcohol sales policy of the county of conviction and were compared. DUI offenders convicted in counties that limit or ban the sale of alcohol were more likely to be male, have more drug problems, meet DSM-IV-TR substance abuse or dependence criteria, and have multiple DUI convictions. Implications for practitioners and policy makers are discussed. 相似文献
243.