Chemistry of <Emphasis Type="Italic">Glossodoris</Emphasis> Nudibranchs: Specific Occurrence of 12-Keto Scalaranes

With the aim of establishing whether the oxidation of the tricyclic carbon skeleton of scalaradial (1) is specific to Glossodoris mollusks, the chemical investigation of specimens of Glossodoris pallida from two distinct geographical areas (China and Guam) and of Glossodoris vespa and Glossodoris averni from Eastern Australia was performed. 12-Deacetoxy-12-oxo-scalaradial (4), recently reported from another Glossodoris nudibranch, was the main metabolite of G. pallida from China, G. vespa, and G. averni. A series of scalarane compounds 3 and 5–11, including the unprecedented 12,16-deacetoxy-12-oxo-scalarafuran 5, was isolated from the mollusks. Interestingly, a population of G. pallida from Guam displayed a different scalarane pattern that was characterized by scalaradial (1), deacetyl scalaradial (2), and deoxoscalarin (3), thus confirming previous reports. The specific occurrence of 12-keto-derivatives in some nudibranchs of the genus Glossodoris is discussed.     

Spaces of Freedom

The predicaments of the current global climate bring a new poignancy and focus to architecture. Emiliano Gandolfi , the curator of the much lauded ‘Experimental Architecture’ exhibition in the Padiglione Italia at the 2008 Venice Biennale, outlines how an emerging group of designers are redefining architecture as they seek to provide solutions that identify people's needs and address the exigencies of global warning, the environmental crisis and migration. Copyright © 2009 John Wiley & Sons, Ltd.     

Cost and Waste Comparison of Reusable and Disposable Shipping Containers for Cut Flowers

Logistics is a fundamental component of the post‐harvest processes, especially in the floricultural sector where the products have to be marketed in short times after the cutting because of their fragility. In the previous years, new approaches to efficiently manage the logistical function and to reduce costs and environmental impacts have been consolidated. In this paper, the investments for two different containers for flower transportation, one disposable and one reusable, are compared, considering a specific supply chain located in central Italy. All data were provided by stakeholders. These were divided into four groups: purchasing, administration, logistical and disposal costs. For the reusable containers, a reverse logistical system, to collect the return components, was hypothesised by using the network analysis tool of the geographic information system (GIS). Results show that the use of a reusable system, which assures a production with less waste and less environmental pressures, is also economically advantageous. Reusable containers involve an initial investment but became cheaper from the second year of the investment and also remained convenient, considering all the costs related to the return collection of the items. Reusable system permits a financial advantage of approximately 140 k€ in total and 21 k€ for each year, considering all the nine years of analysis. Logistics is responsible of the great contribution of total cost in both the reusable and the disposable container (88% and 76%), probably because of the high fragmentation in the delivery service to sale points. Reverse logistics represents the 17% of the reusable container total costs. Copyright © 2011 John Wiley & Sons, Ltd.     

Monte Carlo characterization of materials for prosthetic implants and dosimetric validation of Pinnacle TPS

In external beam radiotherapy the calculation of dose distribution for patients with hip prostheses is critical. Metallic implants not only degrade the image quality but also perturb the dose distribution. Conventional treatment planning systems do not accurately account for high-Z prosthetic implants heterogeneities, especially at interfaces. The materials studied in this work have been chosen on the basis of a statistical investigation on the hip prostheses implanted in 70 medical centres. The first aim of this study is a systematic characterization of materials used for hip prostheses, and it has been provided by BEAMnrc Monte Carlo code. The second aim is to evaluate the capabilities of a specific treatment planning system, Pinnacle³, when dealing with dose calculations in presence of metals, also close to the regions of high-Z gradients. In both cases it has been carried out an accurate comparison versus experimental measurements for two clinical photon beam energies (6 MV and 18 MV) and for two experimental sets-up: metallic cylinders inserted in a water phantom and in a specifically built PMMA slab. Our results show an agreement within 2% between experiments and MC simulations. TPS calculations agree with experiments within 3%.     

Adaptive input shaping for single-link flexible manipulators using an algebraic identification

This work proposes an adaptive control scheme applied to single link-flexible manipulators, which combines a feedback controller of the joint angle with an adaptive input shaper updated by an algebraic non-asymptotic identification. The feedback controller is designed to guarantee trajectory tracking of the joint angle, simplifying thus the input shaper, which can be designed for the arm dynamics only. The input shaper is updated by an algebraic identification of the natural frequency corresponding to the first vibration mode of the arm. In addition, the influence of the assumptions adopted to derive the algebraic identification on the performance of the estimation is studied. Finally, the proposed adaptive control strategy is implemented in practice.     

Model-based optimization of injection strategies for SI engine gas injectors

A mathematical model for the prediction of the mass injected by a gaseous fuel solenoid injector for spark ignition (SI) engines has been realized and validated through experimental data by the authors in a recent work [1]. The gas injector has been studied with particular reference to the complex needle motion during the opening and closing phases. Such motion may significantly affect the amount of injected fuel. When the injector nozzle is fully open, the mass flow depends only on the upstream fluid pressure and temperature. This phenomenon creates a linear relationship between the injected fuel mass and the injection time (i.e. the duration of the injection pulse), thus enabling efficient control of the injected fuel mass by simply acting on the injection time. However, a part of the injector flow chart characterized by strong nonlinearities has been experimentally observed by the authors [1]. Such nonlinearities may seriously compromise the air-fuel mixture quality control and thus increase both fuel consumption and pollutant emissions (SI engine catalytic conversion systems have very low efficiency for non-stoichiometric mixtures). These nonlinearities arise by the injector outflow area variation caused by needle impacts and bounces during the transient phenomena, which occur in the opening and closing phases of the injector. In this work, the mathematical model previously developed by the authors has been employed to study and optimize two appropriate injection strategies to linearize the injector flow chart to the greatest extent. The first strategy relies on injection pulse interruption and has been originally developed by the authors, whereas the second strategy is known in the automotive engine industry as the peak and hold injection. Both injection strategies have been optimized through minimum injection energy considerations and have been compared in terms of linearization effectiveness. Efficient linearization of the injector flow chart has been achieved with both injection strategies, and a similar increase in injector operating range has been observed. The main advantage of the pulse interruption strategy lies on its ease of implementation on existing injection systems because it only requires a simple engine electronic control unit software update. Meanwhile, the peak and hold strategy reveals a substantial lack of robustness and requires expressly designed injectors and electronic components to perform the necessary voltage commutation.     

Indoor levels of volatile organic compounds at Florentine museum environments in Italy

Indoor Air Quality monitoring in cultural institutions is of particular concern to protect these places and the cultural heritage content. An indoor monitoring campaign was performed in three museums in Florence (Italy) to determine the occurrence and levels of volatile organic compounds (VOCs). VOCs of interest included BTEX (benzene, toluene, ethylbenzene, xylenes), terpenes, aldehydes, organic acids, and cyclic volatile methyl siloxanes (cVMS). The most abundant VOCs in all samples analyzed were BTEX, which were strictly related to the traffic source, followed by siloxanes and terpenes. Among BTEX, toluene was always the most abundant followed by xylenes, ethylbenzene, and benzene. cVMS in exhibition rooms with the presence of visitors showed higher values compared to samples collected when the museums were closed. Terpenes showed not only the influence of vegetation-biogenic sources surrounding a museum but could also be related to the wood used for the construction of showcases and furniture and the use of cleaning products. Data obtained also showed the presence of organic acids and aldehydes whose source can be traced back to exhibits themselves and wood-based furniture. Assessing the levels of organic acids in museums is important because, over time, it can cause deterioration of the artifacts.     

From risk factors to detection and intervention: a practical proposal for future work on cyberbullying

While there is an increasing flow of media stories reporting cases of cyberbullying, particularly within online social media, research efforts in the academic community are scattered over different topics across the social science and computer science academic disciplines. In this work, we explored research pertaining to cyberbullying, conducted across disciplines. We mainly sought to understand scholarly activity on intelligence techniques for the detection of cyberbullying when it occurs. Our findings suggest that the vast majority of academic contributions on cyberbullying focus on understanding the phenomenon, risk factors, and threats, with the prospect of suggesting possible protection strategies. There is less work on intelligence techniques for the detection of cyberbullying when it occurs, while currently deployed algorithms seem to detect the problem only up to some degree of success. The article summarises the current trends aiming to encourage discussion and research with a new scope; we call for more research tackling the problem by leveraging statistical models and computational mechanisms geared to detect, intervene, and prevent cyberbullying. Coupling intelligence techniques with specific web technology problems can help combat this social menace. We argue that a multidisciplinary approach is needed, with expertise from human–computer interaction, psychology, computer science, and sociology, for current challenges to be addressed and significant progress to be made.     

Isolation and characterization of novel 2-hydroxy fatty acids from the phospholipids of the spongeSmenospongia aurea

The Caribbean spongeSmenospongia aurea revealed the presence of six novel branched α-hydroxy fatty acids: 2-hydroxy-17-methyloctadecanoic acid, 2-hydroxy-21-methyldocosanoic acid, 2-hydroxy-22-methyltricosanoic acid, 2-hydroxy-22-methyltetracosanoic acid, 2-hydroxy-24-methylpentacosanoic acid, and 2-hydroxy-23-methylpentacosanoic acid. These novel α-hydroxy fatty acids were associated with phosphatidylethanolamine. The spongesAplysina lacunosa andAplysina fistularis also contained considerable amounts of α-hydroxy fatty acids, the very long-chain 5,9,23-tricontatrienoic acid (30∶3), and phytanic acid. The sterol composition of the three sponges was also studied. It indicated thatA. lacunosa andA. fistularis contained large amounts of aplysterol and verongulasterol, whileS. aurea did not show any of these sterols. The results are discussed in terms of the taxonomy of the species.