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A pentapod is usually defined as a 5-degrees-of-freedom fully-parallel manipulator with an axial spindle as moving platform. This kind of manipulators has revealed as an interesting alternative to serial robots handling axisymmetric tools. Their particular geometry permits that, in one tool axis, high inclination angles could be attained, thus overcoming the orientation limits of the classical Stewart-Gough platform. This paper deals with pentapods with coplanar base attachments.In previous works changes in the location of the leg attachments that do not modify the singularity locus of the pentapod were studied. Such leg rearrangements reveal here as a powerful tool to shed light on the geometric structure of the singularity locus and, in particular, on architectural singularities.Indeed, a complete analysis of such singularities is carried out, providing both algebraic conditions, which complete previous results found in literature, and a geometrical interpretation that permits defining a measure of distance to architectural singularities. Such measure can be used as an index in the design process to obtain manipulators as far as possible from architectural singularities, leading to a better global behavior. 相似文献
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Nils‐Jrgen Knudsen Dal Agnese Kocere Jens Wohlmann Simon Van Herck Tobias A. Bauer Julien Resseguier Shahla Bagherifam Hilde Hyldmo Matthias Barz Bruno G. De Geest Federico Fenaroli 《Small (Weinheim an der Bergstrasse, Germany)》2020,16(5)
The zebrafish embryo is a vertebrate well suited for visualizing nanoparticles at high resolution in live animals. Its optical transparency and genetic versatility allow noninvasive, real‐time observations of vascular flow of nanoparticles and their interactions with cells throughout the body. As a consequence, this system enables the acquisition of quantitative data that are difficult to obtain in rodents. Until now, a few studies using the zebrafish model have only described semiquantitative results on key nanoparticle parameters. Here, a MACRO dedicated to automated quantitative methods is described for analyzing important parameters of nanoparticle behavior, such as circulation time and interactions with key target cells, macrophages, and endothelial cells. Direct comparison of four nanoparticle (NP) formulations in zebrafish embryos and mice reveals that data obtained in zebrafish can be used to predict NPs' behavior in the mouse model. NPs having long or short blood circulation in rodents behave similarly in the zebrafish embryo, with low circulation times being a consequence of NP uptake into macrophages or endothelial cells. It is proposed that the zebrafish embryo has the potential to become an important intermediate screening system for nanoparticle research to bridge the gap between cell culture studies and preclinical rodent models such as the mouse. 相似文献
168.
Federico Ciardo Brice Lecampion François Fayard Stéphanie Chaillat 《International journal for numerical methods in engineering》2020,121(24):5696-5718
We present a numerical method for the solution of nonlinear geomechanical problems involving localized deformation along shear bands and fractures. We leverage the boundary element method to solve for the quasi-static elastic deformation of the medium while rigid-plastic constitutive relations govern the behavior of displacement discontinuity (DD) segments capturing localized deformations. A fully implicit scheme is developed using a hierarchical approximation of the boundary element matrix. Combined with an adequate block preconditioner, this allows to tackle large problems via the use of an iterative solver for the solution of the tangent system. Several two-dimensional examples of the initiation and growth of shear-bands and tensile fractures illustrate the capabilities and accuracy of this technique. The method does not exhibit any mesh dependency associated with localization provided that (i) the softening length-scale is resolved and (ii) the plane of localized deformations is discretized a priori using DD segments. 相似文献
169.
de Mello Innocentini Murilo Daniel Lovero Federico Giovanni Ferreira Ariana Silva Das Tapas K. Tronville Paolo 《Clean Technologies and Environmental Policy》2021,23(8):2319-2335
Clean Technologies and Environmental Policy - For decades, wet scrubbers have been used to control particulate matter (PM) emitted by bagasse-fired boilers in the sugarcane industry. This choice... 相似文献
170.
Opening Doors to Future Electrochemical Energy Devices: The Anion‐Conducting Polyketone Polyelectrolytes 下载免费PDF全文
Graeme Nawn Keti Vezzù Gianni Cavinato Giuseppe Pace Federico Bertasi Gioele Pagot Enrico Negro Vito Di Noto 《Advanced functional materials》2018,28(29)
The numerous potential benefits of incorporating anion‐exchange membranes (AEMs), in place of proton‐exchange membranes (PEMs), in energy storage and conversion technologies renders their development of fundamental importance for the continued evolution of alternative energy systems. However, the widespread implementation of AEMs is currently plagued by a range of problems including lower conductivity (with respect to PEMs), poor stability, and high cost. This study reports the conversion of polyketone, one of the world's most mass produced and cheap polymers, to a new highly tuneable polymer architecture, functionalized polyketone (FPK), that demonstrates a range of excellent properties rendering it a significant prospect for AEM materials. The thermal, processing, and ion‐conducting properties of FPK are governed by the amount and nature of the newly formed N‐substituted pyrrole pendant side groups. At 80 °C, the quarternized pyridyl FPK derivative (4MPyrFPK) yields ion‐conductivities of 8.6 and 10.5 mS cm?1 in the iodide and hydroxide forms. In addition, the hydroxide form of 4MPyr‐FPK demonstrates remarkable stability toward the typically problematic alkaline conditions. No chemical decomposition is observed to the membrane after imbibing it in KOH solution for 72 h, and furthermore, the ion‐conductivity is demonstrated to remain constant for at least 30 d at 80 °C. 相似文献