知竹,知足——浅谈紫砂壶“知竹”的文化意境

紫砂壶以造型为基本的载体,通过形神兼备的造型表现出深厚的文化情感,它将自然万物融汇其中,将各种不同的生命、思想和个性呈现其上,使人观壶如同与人交流,产生深刻的情感、精神共鸣,感受到内心的平静,这十分有益于舒缓当代人的精神心理压力,让人们通过泡茶品茗这种生活方式来获得暂时的悠闲,并通过对紫砂壶的把玩来感悟其中的文化内蕴,从而获得自由淡泊的心态,更好地面对生活。本文以紫砂壶“知竹”为例,浅谈其文化意境。     

Microenvironment and related genes predict outcomes of patients with cervical cancer: evidence from TCGA and bioinformatic analysis

Cervical cancer (CESC) is one of the most common cancers and affects the female genital tract. Consistent HPV infection status has been determined to be a vital cause of tumorigenesis. HPV infection may induce changes to the immune system and limit the host’s immune response. Immunotherapy is therefore essential to improving the overall survival of both locally advanced and recurrent CESC patients. Using 304 relevant samples from TCGA, we assessed immune cell function in CESC patients to better understand the status of both tumor micro-environment cells and immune cells in CESC. Functional enrichment analysis, pathway enrichment analysis, and PPI network construction were performed to explore the differentially expressed genes (DEGs). The analysis identified 425 DEGs, which included 295 up-regulated genes and 130 down-regulated genes. We established that upregulation of CCL5 was correlated with significantly better survival, meaning that CCL5 expression could serve as a novel prognostic biomarker for CESC patients. We further focused on CCL5 as a hub gene in CESC, as it had significant correlations with increased numbers of several types of immune cells. Cell-type fractions of M1 macrophages were significantly higher in the high-immune-scores group, which was associated with better overall survival. Finally, we concluded that CCL5 is a promising prognostic biomarker for CESC, as well as a novel chemotherapeutic target.     

马钢张庄矿高压辊磨机装配工艺研究

针对马钢张庄矿高压辊磨机辊套疲劳断裂严重、对辊精度不能满足生产要求等问题，马钢重机公司根据张庄矿实际生产要求对对辊进行国产化，国产化内容包括辊轴、辊套等零部件的新制以及装配工艺攻关，通过技术研发同时结合实际生产经验，成功对高压辊磨机辊套与辊轴以及辊轴与轴承进行装配，完成了张庄矿高压辊磨机整对对辊的国产化，为该型设备后续生产及优化提供了理论和实践参考依据。     

一种可替代漂珠的低密度材料

漂珠低密度水泥浆由于密度低、强度高、体系稳定而在油田低压易漏层及低压油气层长封固段固井作业中获得了广泛的应用。但近年来,由于漂珠的产量越来越少,油田低成本要求急需开发代替漂珠的新型减轻材料,以满足配制低密度水泥浆的需求。开发了BCL-10S低密度混合减轻材料,其物化性能与漂珠相当,用它作减轻剂配制的低密度水泥浆性能与用漂珠作减轻剂配制的低密度水泥浆性能相媲美,并已经在长庆油田获得了应用。     

一种改进的新三步搜索算法

在对三步法工作原理进行研究的基础上提出了新三步搜索算法（NITSS）。该方法充分利用视频序列运动矢量概率分布上的中心偏置特性．在三步搜索算法的基础上引入了十字型分布的4个点构成搜索点群。实验结果表明。新三步搜索算法解决了三步法的小运动估计效果较差问题．提高了搜索精度，保持了三步法的高效率。