Sol–Gel Processing and Characterization of Pure and Metal-Doped SnO2 Thin Films

A chloride-based inorganic sol–gel route was used for preparing pure and metal (osmium, nickel, palladium, platinum)-doped SnO₂ sol. SnCl₄ was first reacted with propanol, then the resulting compound was hydrolyzed and subsequently mixed with solutions of the metal dopants. The obtained sols were used for depositing thin films by spin coating or for preparing powders by solvent evaporation at 110°C. FTIR spectroscopy and thermal analysis of the powders revealed that chlorine still bound to tin stabilized the sol against gelation by hindering the condensation reactions. Film characterizations showed that platinum and palladium, unlike nickel and osmium, were likely to form nanoparticles in the SnO₂ lattice. This result was discussed with regard to the different ways that platinum and palladium, on one hand, and nickel and osmium, on the other, modified the growth of SnO₂ grains and the film roughness and morphology. Dopants that formed nanoparticles (platinum, palladium) resulted in the roughest film, while dopants that did not form particles (nickel, osmium) resulted in SnO₂ grain size very close to that of pure SnO₂.     

Computer-Aided Search for 5-Arylideneimidazolone Anticancer Agents Able To Overcome ABCB1-Based Multidrug Resistance

ABCB1 modulation is an interesting strategy in the search for new anticancer agents that can overcome multidrug resistance (MDR). Hence, 17 new 5-arylideneimidazolones containing an amine moiety, as potential ABCB1 inhibitors, were designed, synthesized, and investigated. The series was tested in both parental (PAR) and multidrug-resistant (MDR) ABCB1-overexpressing T-lymphoma cancer cells using cytotoxicity assays. The ABCB1-modulating activity was examined in rhodamine 123 accumulation tests, followed by Pgp-Glo™ Assay to determine the influence of the most active compounds on ATPase activity. Lipophilic properties were assessed both, in silico and experimentally (RP-TLC). Pharmacophore-based molecular modelling toward ABCB1 modulation was performed. The studies allowed the identification of anticancer agents (p-fluorobenzylidene derivatives) more potent than doxorubicin, with highly selective action on MDR T-lymphoma cells (selectivity index >40). Most of the investigated compounds showed ABCB1-modulating action; in particular, two 5-benzyloxybenzylidene derivatives displayed activity nearly as strong as that of tariquidar.     

Preferences for ancient and modern art museums: Visitor experiences and personality characteristics.

This research has two main purposes. The first is to replicate and possibly to extend the results obtained in a previous study, where the authors found that visitors to the ancient art museum conducted their visit with the primary aim of acquiring understanding and knowledge, while modern art museum visitors conducted their visit with an approach that was primarily emotional and pleasure-seeking. The second purpose relates to studies showing that people who prefer abstract art present higher levels on personality traits like “Openness to Experience” and “Sensation Seeking,” compared to people who prefer realistic art. This study investigates these two personality traits for people who favor visiting museums of ancient rather than modern art. Results confirmed previous findings that emotional aspects related to the visit were relevant for modern art museum visitors, while a more cognitive approach based on learning characterized ancient art museum visitors. Concerning personality traits, no difference was found between the two museum groups on the “Openness to Experience” dimension; differences were found on the “Sensation Seeking” trait; modern art museum visitors attained higher scores as compared to ancient art museum visitors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A flexible multi criteria information filtering model

In this paper, a flexible multi criteria information filtering model is presented. This model is flexible since it allows choosing several distinct criteria, such as content aboutness, coverage, novelty, trust, timeliness, and combining them by a soft aggregation to define a personalized filter. The personal filter is encoded into the user profile that also contains the representations of the user interests that can evolve over time. An implementation of the system applying a combination of the aboutness and coverage criteria has been evaluated and compared to other filtering systems, showing its superior effectiveness. Finally, the possible use of the other criterion is discussed.     

Development and Validation of Europium-Sensitized Luminescence (ESL) Method for the Determination of Tetracycline Residues in Milk

The development of a fast and reliable screening method for the determination of tetracycline residues in milk is described and compared to high-performance liquid chromatography. The method is based on europium-sensitized luminescence: The emissive properties of the lanthanide cation are used as a fingerprint of europium (III) complexation with tetracycline. The optimization of the extraction and purification procedures provided a simple and convenient route to prepare stable tetracycline samples that can safely resist freezing cycles. The method is validated for the first time in milk matrix: The results show that accuracy and precision of the method meet complaints with the criteria of the Commission Decision 2002/657/EC. The proposed method has a false compliant rate (β error) lower than 5%.     

Control of grain size and -orientation in multi-crystalline silicon ingots

Two different cooling rates have been imposed during the early solidification of two multi-crystalline silicon ingots with 250mm diameter and 100mm height in a pilot scale directional solidification furnace. This has been done by opening a variable heat leak system below the crucible in order to achieve a high initial cooling rate in one of the ingots. The grain-structure and -orientation of these two ingots have been investigated by light microscopy (LM) and electron backscattered diffraction (EBSD), and their electrical properties by quasi-steady state photo-conductance (QSSPC) and surface photovoltage (SPV) method. The ingot with the high initial cooling rate shows predominantly grains which are significantly larger than what is usually found in mc-Si. The minority carrier diffusion lengths measured on the large grains in the ingot with high cooling rate show higher values than those measured on the ingot with smaller grains. These results indicate that principles of grain size and -orientation control in mc-Si ingots can be applied to a pilot scale furnace, and the potential for up-scaling to industrial ingots with improved electrical properties and, thus, higher solar cell conversion efficiency.     

Physical workload on neck and upper limb using two CAD applications

The aim was to evaluate (1) the physical workload on neck and upper limb in computer-aided design (CAD) work; (2) the impact of two applications (PROFESSIONAL-CADAM and PRO/Engineering) and (3) two input devices (computer mouse and keyboard), as well as (4) sitting and standing work positions. Fifteen CAD operators were interviewed and examined physically. For nine subjects, the physical workload was measured: electromyography (EMG) of trapezius and forearm extensor muscles, inclinometry of the head, the upper back and upper arms, as well as wrist goniometry. The muscular load was low in CAD work, but the inter-individual variation was considerable. Neither the positions were extreme, nor the movements. The applications, per se, did not have a large impact on the workload, but because of the need for different input devices the effect was strong. Using a keyboard meant higher angular velocities than using a mouse. Hence, when choosing a new software, which requires mainly a mouse as input device, this has to be balanced against the risk of disorders.