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81.
82.
Flora Amato Aniello Castiglione Vincenzo Moscato Antonio Picariello Giancarlo Sperlì 《Multimedia Tools and Applications》2018,77(14):17803-17827
In this work, we propose a novel multimedia summarization technique from Online Social Networks (OSNs). In particular, we model each Multimedia Social Network (MSN)—i.e. an OSN focusing on the management and sharing of multimedia information—using an hypergraph based approach and exploit influence analysis methodologies to determine the most important multimedia objects with respect to one or more topics of interest. Successively, we obtain from the list of candidate objects a multimedia summary using a summarization model together with an heuristics that aims to generate summaries with priority (with respect to some user keywords), continuity, variety and not receptiveness features. The performed experiments on Flickr shows the effectiveness of proposed approach. 相似文献
83.
Leonardo Rundo Carmelo Militello Giorgio Russo Salvatore Vitabile Maria Carla Gilardi Giancarlo Mauri 《Natural computing》2018,17(3):521-536
Despite of the development of advanced segmentation techniques, achieving accurate and reproducible gross tumor volume (GTV) segmentation results is still an important challenge in neuro-radiosurgery. Nowadays, magnetic resonance imaging (MRI) is the most prominent modality in radiation therapy for soft-tissue anatomical districts. Gamma Knife stereotactic neuro-radiosurgery is a minimally invasive technology for dealing with inaccessible or insufficiently treated tumors with traditional surgery or radiotherapy. During a treatment planning phase, the GTV is generally contoured by experienced neurosurgeons and radiation oncologists using fully manual segmentation procedures on MR images. Unfortunately, this operative methodology is definitely time-expensive and operator-dependent. Delineation result repeatability, in terms of both intra- and inter-operator reliability, can be achieved only by using computer-assisted approaches. In this paper a novel semi-automatic seeded image segmentation method, based on a cellular automata model, for MRI brain cancer detection and delineation is proposed. This approach, called GTVcut, employs an adaptive seed selection strategy and helps to segment the GTV, by identifying the target volume to be treated using the Gamma Knife device. The accuracy of GTVcut was evaluated on a dataset composed of 32 brain cancers, using both spatial overlap-based and distance-based metrics. The achieved experimental results are very reproducible, showing the effectiveness and the clinical feasibility of the proposed approach. 相似文献
84.
Guizzardi Giancarlo Sales Tiago Prince Almeida Joo Paulo A. Poels Geert 《Software and Systems Modeling》2022,21(4):1363-1387
Software and Systems Modeling - In recent years, there has been a growing interest in the use of reference conceptual models to capture information about complex and sensitive business domains... 相似文献
85.
Arlati Sara Keijsers Nol Paolini Gabriele Ferrigno Giancarlo Sacco Marco 《Virtual Reality》2022,26(3):885-901
Virtual Reality - Virtual reality (VR) has recently emerged as a promising technology to rehabilitate upper limb functions after stroke. To promote the recovery of functions, retraining... 相似文献
86.
Campo S Nastasi G D'Ascola A Campo GM Avenoso A Traina P Calatroni A Burrascano E Ferlazzo A Lupidi G Gabbianelli R Falcioni G 《The Science of the total environment》2008,403(1-3):148-153
In order to gain more knowledge on the stress responses of gilhead seabream (Sparus aurata) under extreme conditions, this study investigated the functional properties of the hemoglobin system and globin gene expression under hypoxia and low salinity. The oxygen affinity for the two hemoglobin components present inside the S. aurata erythrocyte was practically identical as was the influence of protons and organic phosphates (Root effect). The quantification of S. aurata hemoglobin fractions performed by HPLC and the data on gene expression of globin chains assayed by PCR indicate that under hypoxia and low salinity there is a change in the ratio between the two different hemoglobin components. The result indicating that the distinct hemoglobins present in S. aurata erythrocyte have almost identical functional properties, does not explain the adaptive response (expression change) following exposure of the animal to hypoxia or low salinity on the basis of their function as oxygen transporter. We hypothesize that other parallel biological functions that the hemoglobin molecule is known to display within the erythrocyte are involved in adaptive molecular mechanisms. The autoxidation-reduction cycle of hemoglobin could be involved in the response to particular living conditions. 相似文献
87.
Friddle RW Lemieux MC Cicero G Artyukhin AB Tsukruk VV Grossman JC Galli G Noy A 《Nature nanotechnology》2007,2(11):692-697
Carbon nanotubes display a consummate blend of materials properties that affect applications ranging from nanoelectronic circuits and biosensors to field emitters and membranes. These applications use the non-covalent interactions between the nanotubes and chemical functionalities, often involving a few molecules at a time. Despite their wide use, we still lack a fundamental understanding and molecular-level control of these interactions. We have used chemical force microscopy to measure the strength of the interactions of single chemical functional groups with the sidewalls of vapour-grown individual single-walled carbon nanotubes. Surprisingly, the interaction strength does not follow conventional trends of increasing polarity or hydrophobicity, and instead reflects the complex electronic interactions between the nanotube and the functional group. Ab initio calculations confirm the observed trends and predict binding force distributions for a single molecular contact that match the experimental results. Our analysis also reveals the important role of molecular linkage dynamics in determining interaction strength at the single functional group level. 相似文献
88.
Marzia Pucci Stefania Raimondo Ornella Urzì Marta Moschetti Maria Antonietta Di Bella Alice Conigliaro Nadia Caccamo Marco Pio La Manna Simona Fontana Riccardo Alessandro 《International journal of molecular sciences》2021,22(22)
Tumor-associated macrophages play a key role in promoting tumor progression by exerting an immunosuppressive phenotype associated with the expression of programmed cell death ligand 1 (PD-L1). It is well known that tumor-derived small extracellular vesicles (SEVs) affect the tumor microenvironment, influencing TAM behavior. The present study aimed to examine the effect of SEVs derived from colon cancer and multiple myeloma cells on macrophage functions. Non-polarized macrophages (M0) differentiated from THP-1 cells were co-cultured with SEVs derived from a colorectal cancer (CRC) cell line, SW480, and a multiple myeloma (MM) cell line, MM1.S. The expression of PD-L1, interleukin-6 (IL-6), and other inflammatory cytokines as well as of the underlying molecular mechanisms were evaluated. Our results indicate that SEVs can significantly upregulate the expressions of PD-L1 and IL-6 at both the mRNA and protein levels and can activate the STAT3 signaling pathway. Furthermore, we identified the TLR4/NF-kB pathway as a convergent mechanism for SEV-mediated PD-L1 expression. Overall, these preliminary data suggest that SEVs contribute to the formation of an immunosuppressive microenvironment. 相似文献
89.
Moschetti Michael Xu Alan Schuh Benjamin Hohenwarter Anton Couzinié Jean-Philippe Kruzic Jamie J. Bhattacharyya Dhriti Gludovatz Bernd 《JOM Journal of the Minerals, Metals and Materials Society》2020,72(1):130-138
JOM - Refractory high-entropy alloys (RHEAs) are potential candidate materials for use in next-generation nuclear reactors due to their excellent mechanical performance at high temperatures. Here,... 相似文献
90.