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Domenico Borello Gabriele Gagliardi Giorgia Aimola Valeria Ancona Paola Grenni Giuseppe Bagnuolo Gian Luigi Garbini Ludovica Rolando Anna Barra Caracciolo 《International Journal of Hydrogen Energy》2021,46(16):10131-10142
DDE (2,2-bis (p-chlorophenyl)-1,1-dichloroetylene) is a very persistent and bioaccumulative pesticide and its residues are continuously found in the environment. Among the green remediation strategies for soil recovery, terrestrial Microbial Fuel Cells (MFC) are arousing great interest in scientific community. MFCs transform energy stored in the chemical bonds of organic compounds into electrical energy thanks to exo-electrogen microorganisms naturally occurring in soil, which catalyse oxidation and reduction reactions in the area between two graphite electrodes. This work reports preliminary data on the use of MFCs for promoting soil decontamination from DDE. Several experimental conditions (e.g. addition of compost and open/closed circuit) were applied for assessing how to improve MFC performance in favouring DDE removal. MFCs promoted a significant DDE removal (39%) after 2 months, while at the same time any pesticide decrease was observed in the batch condition. Compost addition stimulated microbial activity and improved MFC performance for a longer time. 相似文献
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Stefano Capizzano Mirko Frappa Francesca Macedonio Enrico Drioli 《Frontiers of Chemical Science and Engineering》2022,16(5):592
One of the problems that most afflicts humanity is the lack of clean water. Water stress, which is the pressure on the quantity and quality of water resources, exists in many places throughout the World. Desalination represents a valid solution to the scarcity of fresh water and several technologies are already well applied and successful (such as reverse osmosis), producing about 100 million m3·d−1 of fresh water. Further advances in the field of desalination can be provided by innovative processes such as membrane distillation. The latter is of particular interest for the treatment of waste currents from conventional desalination processes (for example the retentate of reverse osmosis) as it allows to desalt highly concentrated currents as it is not limited by concentration polarization phenomena. New perspectives have enhanced research activities and allowed a deeper understanding of mass and heat transport phenomena, membrane wetting, polarization phenomena and have encouraged the use of materials particularly suitable for membrane distillation applications. This work summarizes recent developments in the field of membrane distillation, studies for module length optimization, commercial membrane modules developed, recent patents and advancement of membrane material. 相似文献
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Anna Nagurney Patrizia Daniele Giorgia Cappello 《International Transactions in Operational Research》2021,28(1):5-26
In this paper, we demonstrate that, through policy interventions, in the form of subsidies, a system‐optimum for a multiclass human migration network can be achieved, despite the migrants, who can be refugees, behaving in a user‐optimized manner. The formulation and analysis are conducted using variational inequality theory. The policy intervention allows governmental decision‐makers to moderate the flow of migrants while enhancing societal welfare. An algorithm is proposed and applied to compute the solutions to a series of numerical examples, with changes in initial populations and utility functions, inspired by a pandemic, followed by a natural disaster. 相似文献
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Dante Rotili Dr. Domenico Tarantino Dr. Vincenzo Carafa Dr. Ester Lara Dr. Sarah Meade Dr. Giorgia Botta Dr. Angela Nebbioso Dr. Jörg Schemies Dr. Manfred Jung Prof. Aleksey G. Kazantsev Prof. Manel Esteller Prof. Mario F. Fraga Dr. Lucia Altucci Prof. Antonello Mai Prof. 《ChemMedChem》2010,5(5):674-677
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Luca Antonioli Carolina Pellegrini Matteo Fornai Laura Benvenuti Vanessa DAntongiovanni Rocchina Colucci Lorenzo Bertani Clelia Di Salvo Giorgia Semeghini Concettina La Motta Laura Giusti Lorenzo Zallocco Maurizio Ronci Luca Quattrini Francesco Angelucci Vito Coviello Won-Keun Oh Quy Thi Kim Ha Zoltan H. Nmeth Gyorgy Hask Corrado Blandizzi 《International journal of molecular sciences》2021,22(12)
Acadesine (ACA), a pharmacological activator of AMP-activated protein kinase (AMPK), showed a promising beneficial effect in a mouse model of colitis, indicating this drug as an alternative tool to manage IBDs. However, ACA displays some pharmacodynamic limitations precluding its therapeutical applications. Our study was aimed at evaluating the in vitro and in vivo effects of FA-5 (a novel direct AMPK activator synthesized in our laboratories) in an experimental model of colitis in rats. A set of experiments evaluated the ability of FA5 to activate AMPK and to compare the efficacy of FA5 with ACA in an experimental model of colitis. The effects of FA-5, ACA, or dexamethasone were tested in rats with 2,4-dinitrobenzenesulfonic acid (DNBS)-induced colitis to assess systemic and tissue inflammatory parameters. In in vitro experiments, FA5 induced phosphorylation, and thus the activation, of AMPK, contextually to the activation of SIRT-1. In vivo, FA5 counteracted the increase in spleen weight, improved the colon length, ameliorated macroscopic damage score, and reduced TNF and MDA tissue levels in DNBS-treated rats. Of note, FA-5 displayed an increased anti-inflammatory efficacy as compared with ACA. The novel AMPK activator FA-5 displays an improved anti-inflammatory efficacy representing a promising pharmacological tool against bowel inflammation. 相似文献
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