Life cycle energy and carbon footprint analysis of photovoltaic battery microgrid system in India

Electricity supply in India is from a centralized grid. Many parts of the country experience grid interruptions. Life cycle energy and environmental analysis has been done for a 27 kWp photovoltaic system which acts as grid backup for 3 h outage in an Indian urban residential scenario. This paper discusses energy requirements and carbon emission for a PV storage system for five different battery technologies in Indian context. This can be used as a metric for comparative analysis for new batteries, with an undeveloped market. The energy requirements for the components are quantified and are compared in terms of energy payback time (EPBT) and Net Energy Ratio (NER). All the calculations are done for Indian context. EPBT is found to be in the range of 2–4.5 years for all the systems, while NER is in the range of 6.6–2.52. NaS has the highest emission factor of 0.67 kgCO₂/kWh and the least for NiCd (0.091 kgCO₂/kWh). These factors can be used to select a PV battery option and to target selection of materials and systems based on the reported values.     

Evaluation of potential anti‐cancer activity of cationic liposomal nanoformulated Lycopodium clavatum in colon cancer cells

Research dealing with early diagnosis and efficient treatment in colon cancer to improve patient''s survival is still under investigation. Chemotherapeutic agent result in high systemic toxicity due to their non‐specific actions on DNA repair and/or cell replication. Traditional medicine such as Lycopodium clavatum (LC) has been claimed to have therapeutic potentials against cancer. The present study focuses on targeted drug delivery of cationic liposomal nanoformulated LC (CL‐LC) in colon cancer cells (HCT15) and comparing the efficacy with an anti‐colon cancer drug, 7‐ethyl‐10‐hydroxy‐camptothecin (SN38) along with its nanoformulated form (CL‐SN38). The colloidal suspension of LC was made using thin film hydration method. The drugs were characterised using ultraviolet, dynamic light scattering, scanning electron microscopy, energy, dispersive X‐ray spectroscopy. In vitro drug release showed kinetics of 49 and 89% of SN38 and LC, whereas CL‐SN38 and CL‐LC showed 73 and 74% of sustained drug release, respectively. Studies on morphological changes, cell viability, cytotoxicity, apoptosis, cancer‐associated gene expression analysis of Bcl‐2, Bax, p53 by real‐time polymerase chain reaction and western blot analysis of Bad and p53 protein were performed. Nanoformulated LC significantly inhibited growth and increased the apoptosis of colon cancer cells indicating its potential anti‐cancer activity against colon cancer cells.Inspec keywords: cancer, biological organs, cellular biophysics, drug delivery systems, drugs, nanomedicine, genetics, DNA, molecular biophysics, biochemistry, lipid bilayers, toxicology, suspensions, colloids, light scattering, X‐ray chemical analysis, solvation, enzymes, nanostructured materialsOther keywords: energy dispersive X‐ray spectroscopy, in vitro drug release, morphological changes, cell viability, cytotoxicity, apoptosis, cancer‐associated gene expression analysis, Bcl‐2, Bax, real‐time polymerase chain reaction, western blot analysis, Bad protein, p53 protein, scanning electron microscopy, dynamic light scattering, ultraviolet scattering, thin film hydration method, colloidal suspension, nanoformulated form CL‐SN38, 7‐ethyl‐10‐hydroxy‐camptothecin, anticolon cancer drug, colon cancer cells HCT15, cationic liposomal nanoformulated LC, targeted drug delivery, therapeutic potentials, Lycopodium clavatum, traditional medicines, cell replication, DNA repair, nonspecific actions, high systemic toxicity, chemotherapeutic agents, patient survival, colon cancer treatment, colon cancer diagnosis, CL‐LC, potential anticancer activity     

Exponentially Accurate Approximations to Periodic Lipschitz Functions Based on Fourier Series Partial Sums

The problem of accurately reconstructing a piecewise smooth. 2-periodic function f and its first few derivatives, given only a truncated Fourier series representation of f, is studied and solved. The reconstruction process is divided into two steps. In the first step, the first 2N + 1 Fourier coefficients of f are used to approximate the locations and magnitudes of the discontinuities in f and its first M derivatives. This is accomplished by first finding initial estimates of these quantities based on certain properties of Gibbs phenomenon, and then refining these estimates by fitting the asymptotic form of the Fourier coefficients to the given coefficients using a least-squares approach. The locations of the singularities are approximated to within O(N ^–M–2), and the associated jump of the kth derivative of f is approximated to within O(N ^–M–1+k ), as N , and the method is robust. These estimates are then used with a class of singular basis functions, which have certain built-in singularities, to construct a new sequence of approximations to f. Each of these new approximations is the sum of a piecewise smooth function and a new Fourier series partial sum. When N is proportional to M, it is shown that these new approximations, and their derivatives, converge exponentially in the maximum norm to f, and its corresponding derivatives, except in the union of a finite number of small open intervals containing the points of singularity of f. The total measure of these intervals decreases exponentially to zero as M . The technique is illustrated with several examples.     

A self-configurable large-scale virtual manufacturing environment for collaborative designers

As manufacturing environments are getting distributed and increasing in size, the related virtual environments are getting larger and more closely networked together. This trend has led to a new paradigm—large-scale virtual manufacturing environment (LSVME). It supports networked and distributed virtual manufacturing to meet manufacturing system requirements. Since it contains a large number of virtual components, an effective data structure and collaborative construction methodology are needed. A metaearth architecture is proposed as the data structure for representing LSVME. This architecture consists of virtual space layer, mapping layer, library layer and ontology layers, which describe interaction among virtual components and has the ability to analyze the characteristics of virtual environment. In addition, it increases reusability of virtual components and supports self-reconfiguration for manufacturing simulation. A heuristic construction method based on graph theory is proposed using this architecture. It prevents redundant design of virtual components and contributes to an effective construction scheduling technique for collaborative designers.     

Architectural design and FPGA implementation of radix-4 CORDIC processor

A new scaled radix-4 CORDIC architecture that incorporates pipelining and parallelism is presented. The latency of the architecture is n/2 clock cycles and throughput rate is one valid result per n/2 clocks for n bit precision. A 16 bit radix-4 CORDIC architecture is implemented on the available FPGA platform. The corresponding latency of the architecture is eight clock cycles and throughput rate is one valid result per eight clock cycles. The entire scaled architecture operates at 56.96 MHz of clock rate with a power consumption of 380 mW. The speed can be enhanced with the upgraded version of FPGA device. A speed-area optimized processor is obtained through this architecture and is suitable for real time applications.     

Inventory model for seasonal demand with option to change the market

In real life, when bulk purchase becomes convenient or even mandatory, it is a common practice for distributors to explore an alternative market in order to maximize the revenue earned. In this paper, we consider an inventory model for a product having seasonal demand with two potential markets, say, primary and alternate. The distributor has a single opportunity of procurement prior to multiple demand seasons in the primary and the alternate market. Both the markets have similar demand patterns, with time lag between their demand seasons. The demand is a price and time dependent function with increasing, constant and declining phases within each demand season. The scale parameter of demand rate depends upon the market. In each market, successive seasons are separated by random time. In one replenishment cycle, the distributor has a single option to exit the primary market by transferring the inventory, with or without change in selling price. This option can be exercised at the end of any complete season at the primary market. Our investigations indicate that it will be beneficial for the distributor to shift to the alternate market even at a slightly lower selling price if demand rate in the alternate market is higher. Optimal number of seasons at the primary market before change of price or market is obtained. Optimal policy is obtained for jointly determining the order quantity and price. Concavity of the profit function is discussed. Solution procedure, numerical examples and sensitivity analysis are presented.     

A general framework for efficient geographic routing in wireless networks

We propose a new link metric called normalized advance (NADV) for geographic routing in multihop wireless networks. NADV selects neighbors with the optimal trade-off between proximity and link cost. Coupled with the local next hop decision in geographic routing, NADV enables an adaptive and efficient cost-aware routing strategy. Depending on the objective or message priority, applications can use the NADV framework to minimize various types of link cost.We present efficient methods for link cost estimation and perform detailed experiments in simulated environments. Our results show that NADV outperforms current schemes in many aspects: for example, in high noise environments with frequent packet losses, the use of NADV leads to 81% higher delivery ratio. When compared to centralized routing under certain settings, geographic routing using NADV finds paths whose cost is close to the optimum. We also conducted experiments in Emulab testbed and the results demonstrate that our proposed approach performs well in practice.     

Spectral entropy and spectral shape based pre-quantization for real time speaker identification system

Pre-processing is one of the vital steps for developing robust and efficient recognition system. Better pre-processing not only aid in better data selection but also in significant reduction of computational complexity. Further an efficient frame selection technique can improve the overall performance of the system. Pre-quantization (PQ) is the technique of selecting less number of frames in the pre-processing stage to reduce the computational burden in the post processing stages of speaker identification (SI). In this paper, we develop PQ techniques based on spectral entropy and spectral shape to pick suitable frames containing speaker specific information that varies from frame to frame depending on spoken text and environmental conditions. The attempt is to exploit the statistical properties of distributions of speech frames at the pre-processing stage of speaker recognition. Our aim is not only to reduce the frame rate but also to maintain identification accuracy reasonably high. Further we have also analyzed the robustness of our proposed techniques on noisy utterances. To establish the efficacy of our proposed methods, we used two different databases, POLYCOST (telephone speech) and YOHO (microphone speech).     

Differential regulation of redox proteins and chaperones in HbEβ-thalassemia erythrocyte proteome

Purpose: In (hemoglobin, Hb) HbEβ‐thalassemia, HbE (β‐26 Glu→Lys) interacts with β‐thalassemia to produce clinical manifestation of varying severity. This is the first proteomic effort to study changes in protein levels of erythrocytes isolated from HbEβ‐thalassemic patients compared to normal. Experimental design: We have used 2‐DE and MALDI‐MS/MS‐based techniques to investigate the differential proteome profiling of membrane and Hb‐depleted fraction of cytosolic proteins of erythrocytes isolated from the peripheral blood samples of HbEβ‐thalassemia patients and normal volunteers. Results: Our study showed that redox regulators such as peroxiredoxin 2, Cu‐Zn superoxide dismutase and thioredoxin and chaperones such as α‐hemoglobin stabilizing protein and HSP‐70 were upregulated in HbEβ‐thalassemia. We have also observed larger amounts of membrane associated globin chains and indications of disruption of spectrin‐based junctional complex in the membrane skeleton of HbEβ‐thalassemic erythrocytes upon detection of low molecular weight fragments of β‐spectrin and decrease in β‐actin and dematin content. Conclusion and clinical relevance: We have observed interesting changes in the proteomic levels of redox regulators and chaperons in the thalassemic hemolysates and have observed strong correlation or association of the extent of such proteomic changes with HbE levels. This could be important in understanding the role of HbE in disease progression and pathophysiology.     

Effect of numerical integration on meshless methods

In this paper, we present the effect of numerical integration on meshless methods with shape functions that reproduce polynomials of degree k1. The meshless method was used on a second order Neumann problem and we derived an estimate for the energy norm of the error between the exact solution and the approximate solution from the meshless method under the presence of numerical integration. This estimate was obtained under the assumption that the numerical integration scheme satisfied a form of Green’s formula. We also indicated how to obtain numerical integration schemes satisfying this property.