Semantics-driven annotation of patient-specific 3D data: a step to assist diagnosis and treatment of rheumatoid arthritis

In the digital era, patient-specific 3D models (3D-PSMs) are becoming increasingly relevant in computer-assisted diagnosis, surgery training on digital models, or implant design. While advanced imaging and reconstruction techniques can create accurate and detailed 3D models of patients’ anatomy, software tools that are able to fully exploit the potential of 3D-PSMs are still far from being satisfactory. In particular, there is still a lack of integrated approaches for extracting, coding, sharing and retrieving medically relevant information from 3D-PSMs and use it concretely as a support to diagnosis and treatment. In this article, we propose the SemAnatomy3D framework, which demonstrates how the ontology-driven annotation of 3D-PSMs and of their anatomically relevant features (parts of relevance) can assist clinicians to document more effectively pathologies and their evolution. We exemplify the idea in the context of the diagnosis of rheumatoid arthritis of the hand district, and show how feature extraction tools and semantic 3D annotation can provide a rich characterization of anatomical landmarks (e.g., articular facets, prominent features, ligament attachments) and pathological markers (erosions, bone loss). The core contributions are an ontology-driven part-based annotation method for the 3D-PSMs and a novel automatic localization of erosion and quantification of the OMERACT RAMRIS erosion score. Finally, our results have been compared against a medical ground truth.     

Experimental realization of quantum cheque using a five-qubit quantum computer

Quantum cheques could be a forgery-free way to make transaction in a quantum networked banking system with perfect security against any no-signalling adversary. Here, we demonstrate the implementation of quantum cheque, proposed by Moulick and Panigrahi (Quantum Inf Process 15:2475–2486, 2016), using the five-qubit IBM quantum computer. Appropriate single qubit, CNOT and Fredkin gates are used in an optimized configuration. The accuracy of implementation is checked and verified through quantum state tomography by comparing results from the theoretical and experimental density matrices.     

Kinetics of alpha precipitation in Ti-6 wt % Cr and Ti-11 wt % Mo

The morphology and kinetics of the precipitation of the alpha phase produced by two different heat treatment routes, namely, (a) direct isothermal decomposition and (b)-quenching and subsequent ageing, were studied. In isothermally decomposed samples the (supersaturated) + transformation was seen to occur mainly through the discontinuous growth of the transformed zone consisting of groups of parallel side plates from the grain boundary regions towards the interior of the grain. Unlike for the case of a regular discontinuous precipitation, here the transformed regions are not separated from the untransformed by an incoherent interface and the growing-plates do obey a fixed orientation relationship with the grain from which they are evolved. The theory of cellular reaction has been applied to explain the growth rate of the duplex ( + ) region. The overall reaction kinetics were analysed on the basis of the Johnson-Mehl formulation and were found to be consistent with that of a discontinuous precipitation reaction, where grain boundary nucleation sites were saturated at an early stage of the transformation. The structure of the-quenched samples showed a uniform distribution of athermal omega particles which acted as precursors to the-precipitates. As a consequence, the reaction rate was greatly enhanced and-precipitation in the quenched and aged samples was seen to occur continuously in the entire body of the grain.     

Energy storage behaviour of some binary alkali borate glasses by thermoluminescence studies

Thermoluminescence behaviour of a series of binary alkali borate glasses has been investigated to study their energy storage mechanism. Sodium borate glasses of varying composition have been prepared and their glow curves recorded after exposing them to X-rays (CuK radiation, 30 kV, 10 mA) of different dosages at room temperature. The effect of the nature and concentration of alkali oxide and the dose of irradiation on the nature of thermoluminescent glow curves were also studied. Borate glasses containing different concentrations of Na₂O exhibit significantly different glow curves. These glow curves have been analysed and the nature of traps responsible for TL emission are tentatively identified. The broad and complex nature of the glow pattern is attributed to distribution of trap depths in these materials. The viability of borate glasses in the construction of TL dosimeters are discussed.     

Analyzing collective behavior from blogs using swarm intelligence

With the rapid growth of the availability and popularity of interpersonal and behavior-rich resources such as blogs and other social media avenues, emerging opportunities and challenges arise as people now can, and do, actively use computational intelligence to seek out and understand the opinions of others. The study of collective behavior of individuals has implications to business intelligence, predictive analytics, customer relationship management, and examining online collective action as manifested by various flash mobs, the Arab Spring (2011) and other such events. In this article, we introduce a nature-inspired theory to model collective behavior from the observed data on blogs using swarm intelligence, where the goal is to accurately model and predict the future behavior of a large population after observing their interactions during a training phase. Specifically, an ant colony optimization model is trained with behavioral trend from the blog data and is tested over real-world blogs. Promising results were obtained in trend prediction using ant colony based pheromone classier and CHI statistical measure. We provide empirical guidelines for selecting suitable parameters for the model, conclude with interesting observations, and envision future research directions.     

Reducing congestion in bulk-service finite-buffer queueing system using batch-size-dependent service

In the design and analysis of any queueing system, one of the main objectives is to reduce congestion which can be achieved by controlling either arrival-rates or service-rates. This paper adopts the latter approach and analyzes a single-server finite-buffer queue where customers arrive according to the Poisson process and are served in batches of minimum size a with a maximum threshold limit b. The service times of the batches are arbitrarily distributed and depends on the size of the batches undergoing service. We obtain the joint distribution of the number of customers in the queue and the number with the server, and distributions of the number of customers in the queue, in the system, and the number with the server. Various performance measures such as the average number of customers in the queue (system) and with the server etc. are obtained. Several numerical results are presented in the form of tables and graphs and it is observed that batch-size-dependent service rule is more effective in reducing the congestion as compared to the one when service rates of the batches remain same irrespective of the size of the batch. This model has potential application in manufacturing, computer-communication network, telecommunication systems and group testing.     

Growth of La2Mo2O9 films on porous Al2O3 substrates by radio frequency magnetron sputtering

Synthesis conditions of La₂Mo₂O₉ thin film by radio frequency (RF) sputtering technique on Al₂O₃ ceramic substrates are studied. It is found that the deposition temperature and oxygen partial pressure are the most important factors for obtaining pure La₂Mo₂O₉ films. Varying both parameters, Mo-rich, stoichiometric, and Mo-deficient films are obtained. With increasing the La:Mo ratio, films become denser. A crust layer is observed on top of the Mo-rich and the Mo-deficient films. The formation of the La₂Mo₂O₉ phase is discussed with respect to the sputtering mechanism.     

Transmission through the band-gap states in Schottky-barrier carbon nanotube transistors

We have studied the minimum off-state leakage current of ultrascaled Schottky-barrier carbon nanotube transistors (SBCNTs) with midgap Schottky-barrier source/drain contacts. The off-state leakage current is separated into two parts: thermal emission around the top of the Schottky barrier and tunneling through the evanescent band-gap states. Because the transmission through deep band-gap states makes a dominant contribution for ultrascaled SBCNTs, the off-state minimum leakage current increases exponentially with decreasing scaling length of SBCNTs.     

An electrochemical technique to deposit thin films of PbTe

PbTe thin films were deposited electrochemically on transparent conducting oxide coated (TCO) glass substrates from a solution of lead acetate and TeO₂ at low pH. A lead (Pb) strip was used as a sacrificing anode and the TCO glass acted as the cathode, which were short-circuited externally. Depositions were carried out at different temperatures of the bath to study the growth kinetics and grain growth. X-ray diffraction technique, scanning electron microscopy, infrared spectroscopy and resistivity measurements were carried out to characterize the deposited films. The films were polycrystalline in nature with a cubic phase.