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11.
The relation between muscle pain, muscle activity, and muscle co-ordination is still controversial. The present human study investigates the influence of experimental muscle pain on resting, static, and dynamic muscle activity. In the resting and static experiments, the electromyography (EMG) activity and the contraction force of m. tibialis anterior were assessed before and after injection of 0.5 ml hypertonic saline (5%) into the same muscle. In the dynamic experiment, injections of 0.5 ml hypertonic saline (5%) were performed into either m. tibialis anterior (TA) or m. gastrocnemius (GA) and the muscle activity and co-ordination were investigated during gait on a treadmill by EMG recordings from m. TA and m. GA. At rest no evidence of EMG hyperactivity was found during muscle pain. The maximal voluntary contraction (MVC) during muscle pain was significantly lower than the control condition (P < 0.05). During a static contraction at 80% of the pre-pain MVC muscle pain caused a significant reduction in endurance time (P < 0.043). During dynamic contractions, muscle pain resulted in a significant decrease of the EMG activity in the muscle, agonistic to the painful muscle (P < 0.05), and a significant increase of the EMG activity of the muscle, antagonistic to the painful muscle (P < 0.05). Muscle pain seems to cause a general protection of painful muscles during both static and dynamic contractions. The increased EMG activity of the muscle antagonistic to the painful muscle is probably a functional adaptation of muscle co-ordination in order to limit movements. Modulation of muscle activity by muscle pain could be controlled via inhibition of muscles agonistic to the movement and/or excitation of muscles antagonistic to the movement. The present results are in accordance with the pain-adaptation model (Lund, J.P., Stohler, C.S. and Widmer, C.G. In: H. Vaer?y and H. Merskey (Eds.), Progress in Fibromyalgia and Myofascial Pain. Elsevier, Amsterdam, 1993, pp. 311-327.) which predicts increased activity of antagonistic muscle and decreased activity of agonistic muscle during experimental and clinical muscle pain.  相似文献   
12.
13.
The influence of NaCl and CO2 on the atmospheric corrosion of magnesium alloy AZ91 is studied in the laboratory. Samples were exposed under carefully controlled air and flow conditions; the relative humidity was 95%, the temperature was 22.0°C and the concentration of CO2 was < 1 ppm or 350 ppm. Different amounts of sodium chloride (0–70 μg/cm2) were added before exposure. The corrosion products were analyzed by gravimetry, ion chromatography, X‐ray diffraction and scanning electron microscopy. Mass gain and metal loss results are reported. The combination of high humidity and NaCl is very corrosive towards AZ91. However, the NaCl‐induced corrosion is inhibited by ambient concentrations of CO2. Exposure in the absence of CO2 gives rise to heavy pitting, with brucite, Mg(OH)2, being the dominant corrosion product. In the presence of CO2 a layer of hydrated magnesium hydroxy carbonate, Mg5(CO3)4(OH)2 · 5 H2O forms. A tentative corrosion mechanism is presented that explains the behavior in the two environments.  相似文献   
14.
This article focuses on the detailed microstructural investigation of the oxide scale formed on a 304 steel in the presence of oxygen and water vapour (40%) at 600 °C. The work has been carried out using a combination of microanalytical techniques including FIB, TEM, EDX and electron diffraction. The local breakdown of the initially protective oxide scale and the growth of island/crater oxide morphology are described. Special consideration is given to the influence of the microstructure of the steel and the oxide scale on the breakdown behaviour.  相似文献   
15.
The distribution of the sum of a finite number of identically distributed random variables is in many cases easily determined given that the variables are independent. The moments of any order of the sum can always be expressed by the moments of the single term without computational problems. However, in the case of dependency between the terms even calculation of a few of the first moments of the sum presents serious computational problems.By use of computerized symbol manipulations it is practicable to obtain exact moments of partial sums of stationary sequences of mutually dependent lognormal variables or polynomials of standard Gaussian variables. The dependency structure is induced by specifying the autocorrelation structure of the sequence of standard Gaussian variables. Particularly useful polynomials are the Winterstein approximations that distributionally fit with non-Gaussian variables up to the moments of the fourth order [Winterstein, S. R. Nonlinear vibration models for extremes and fatigue. J. Engng Mech. ASCE 114 (1988) 1772–1790]1. A method to obtain the Winterstein approximation to a partial sum of a sequence of Winterstein approximations is explained and results are given for different autocorrelation functions of the generic Gaussian sequence.The primary purpose of the investigation is to provide a tool for judging the validity of the central limit theorem argument in specific applicational situations occurring in stochastic mechanics, that is, to judge the speed of convergence of the distribution of a sum (or an integral) of mutually dependent random variables to the Gaussian distribution. The paper is closely related to the work in Ditlevsen et al. [Ditlevsen, O., Mohr, G. & Hoffmeyer, P. Integration of non-Gaussian fields. Prob. Engng Mech 11 (1996) 15–23]2.  相似文献   
16.
Mechanical testing and ultrasonic measurements were used to establish the properties of metamorphic rocks in different directions of the foliation plane. Tests were undertaken on 42 mm diameter specimens cored at right angles to the foliation of gneissic rocks from southwest Sweden. Ultrasonic and tensile testing was carried out in three diametral directions and the data for each direction were compared. Coefficients, failure load anisotropy and velocity anisotropy were obtained. An anisotropy coefficient of 3% was detected by ultrasonic measurements, while the Brazilian tests indicated 15%. The study has shown that an anisotropy coefficient of the foliation plane is present, albeit small. Electronic Publication  相似文献   
17.
The stability problem for an elasticallu supported column subject to a varying axial force has been solved by means of a general numerical procedure based on Galerkin's method. Apart from the intrinsic value of the solution itself, its possible value modelling some complex stability problems in the area of restrained lateral-torsional stability problems is demonstrated and specific numerical solutions are applied to the case of lateral buckling of the free flange of a composite girder. The results obtained are discussed and suggestions for additional investigations are presented.  相似文献   
18.
Thin films of amorphous and polycrystalline tungsten oxide were produced by reactive dc magnetron sputtering and nanocrystalline films were deposited by advanced gas evaporation. The films were submitted to electrochemical intercalation of Li ions before infrared reflectance measurements were carried out. For crystalline films, the reflectance in the wavelength region 10–30 μm increases upon intercalation, indicating an increasing free-electron contribution. On the other hand, all the films display an increased absorption at wavelengths less than 10 μm when intercalated. The thermal emittance could be varied from about 0.5 to 0.7–0.75 by intercalation in films with thicknesses in excess of 1 μm. Both absorption and interference contribute to the emittance contrast.  相似文献   
19.
The effect of 2 months of treatment with the oral growth hormone (GH) secretagogue MK-677 on markers of bone metabolism was determined in healthy obese male subjects. This was a randomized, double-blind, parallel, placebo-controlled study. Twenty-four healthy obese males, 19-49 years of age, with body mass index > 30 kg/m2 were treated with MK-677 (25 mg/day; n = 12) or placebo (n = 12) for 8 weeks. MK-677 increased markers of bone formation; a 23% increase in the carboxy-terminal propeptide of type I procollagen levels and a 28% increase in procollagen III peptide levels were seen with as little as 2 weeks of MK-677 treatment (p < 0.01 and p = 0.001 vs. placebo, respectively) while a 15% increase in serum levels of osteocalcin was not detected until 8 weeks of treatment (p < 0.01 vs. placebo). Markers of bone resorption were induced within 2 weeks of treatment with MK-677; serum levels of the carboxy-terminal cross-linked telopeptide of type I collagen were increased 26% at 8 weeks (p = 0.001 vs. placebo), and urine hydroxyproline/creatinine and calcium/creatinine ratios at 8 weeks were increased by 23% (p < 0.05 vs. placebo) and 46% (p < 0.05 vs placebo), respectively, MK-677 increased serum insulin-like growth factor binding protein-5 (IGFBP-5) by 43-44% after 2-8 weeks of treatment (p < 0.01 vs. placebo). Serum IGFBP-4 was increased by 25% after 2 weeks of treatment (p < 0.001 vs. placebo) but no significant change from baseline was observed after 8 weeks of treatment. Plasma interleukin-6 was not significantly changed by active treatment. In conclusion, short-term treatment of healthy obese male volunteers with the GH secretagogue MK-677 increases markers of both bone resorption and formation. Large increases in serum levels of IGF-1 and IGFBP-5 and a transient increase in serum IGFBP-4 were found. Future long-term studies are needed to investigate if prolonged treatment with MK-677 increases bone mass.  相似文献   
20.
We correct for the effect of temperature induced frequency shifts on the observed dynamic structure factor S(q,) and find that the intrinsic behavior for non-superfluid4He is remarkably similar to that for other noble-gas fluids.  相似文献   
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