Identifiability of nonlinear systems with application to HIV/AIDS models

In this note, we investigate different concepts of nonlinear identifiability in the generic sense. We work in the linear algebraic framework. Necessary and sufficient conditions are found for geometrical identifiability, algebraic identifiability and identifiability with known initial conditions. Relationships between different concepts are characterized. Constructive procedures are worked out for both generic geometrical and algebraic identifiability of nonlinear systems. As an application of the theory developed, we study the identifiability properties of a four dimensional model of HIV/AIDS. The questions answered in this study include the minimal number of measurement of the variables for a complete determination of all parameters and the best period of time to make such measurements. This information will be useful in formulating guidelines for clinical practice.     

BC480-22/42支架液压系统的大流量技术改造

分析了BC-480支架在综采工作面使用中液压系统配置低的原因,提出了系统的改造原则和方案,比较了改制前后支架的动作速度.     

竞争条件下政府干预经济探析

分析了竞争条件下政府干预经济的原因,阐述了政府干预经济的作用,进而指出了政府干预经济存在的一些失误,提出政府干预经济应注意的问题,从而形成一个平等、高效的市场经济局面。     

垂直管吸收器内泡式吸收过程的数值研究

建立垂直管吸收器管内泡式吸收过程中传热传质的数学物理模型，对其泡式吸收过程进行数值研究，获得泡式吸收方式的一些传热传质特性，为吸收器的优化设计提供一定理论指导。     

基于SPA的模式识别

发展和深化了集对分析（SPA）基础理论，并在此基础上探讨了基于集对分析的模式识别方法，给出了集对模式识别的三个判定原则，这对SPA的发展及其在模式识别中的应用提供了理论支持。     

四川马海毛钢花呢的试制

根据四川马海毛原料资源的品质特性，运用精纺粗做的方法，成功地试制出手感滑糯而富有弹性、光泽明亮悦目，各项物理指标符合FZ/T24002-93标准的四川马海毛纯毛钢花呢，达到了马海毛产品的特殊风格。同时指出四川马海毛制成率偏低。     

冠心病患者循环血中内皮细胞、内皮素和6－酮－前列环素F_（1a）的动态变化及意义

以循环内皮细胞（ＣＥＣ）作为血管内皮细胞（ＶＥＣ）损伤的指示物，以血浆内皮素（ＥＴ）和前列环素（ＰＧＩ２）反映ＶＥＣ的功能变化，对８５例冠心病患者与３０例正常人进行对比研究，并对５０例不稳定型心绞痛及２０例急性心肌梗塞进行了动态观察．结果表明：冠心病外周血中ＣＥＣ、ＥＴ明显升高（Ｐ＜０．００１），ＰＧＩ２明显下降（Ｐ＜０．００１），尤以不稳定型心绞痛和急性心肌梗塞更显著，与病情的严重程度相一致．提示冠心病ＶＥＣ损伤，以及它所分泌的内皮源性舒缩因子失平衡参与了冠心病的病理过程。     

Intercellular communication between dorsal root ganglion cells and colonic smooth muscle cells in vitro

This study demonstrates that the use of high field 1H NMR spectroscopy permits individual detection of phosphatidylcholine and sphingomyelin molecules at the surface of native low density lipoprotein (LDL) particles. Distinct behaviour was observed for the choline head group -N(CH3)3 resonances of these different phospholipids revealing preferential immobilisation for phosphatidylcholine. This suggests the existence of reversible and irreversible phosphatidylcholine-apolipoprotein B interactions and is consistent with microdomain formation at the surface monolayer of LDL. The novel resonance assignment and results show that 1H NMR can provide efficient and practical means for future studies on the structure and dynamics at the LDL surface.