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1.
Mohd Hilmi Hasan Jafreezal Jaafar Mohd Fadzil Hassan 《Artificial Intelligence Review》2014,42(4):835-850
Monitoring Quality of Service (QoS) compliance is an important procedure in web service environment. It determines whether users’ expectations are met, and becomes the vital factor for them to decide whether to continue paying for the service or not. The monitoring is performed by checking the actual services performance against the QoS stated in Service Level Agreement (SLA). In relation to that, the need for monitoring vague QoS specifications in SLA has become more apparent nowadays. This paper reviews the published literature on web services QoS monitoring. A total of 60 selected articles were systematically analyzed. There were 23 of the articles selected through restrictive search criteria while the other 37 were selected based on unrestrictive search criteria. The review shows that little evidence exists on monitoring vague QoS specifications of web services. Providing ability for monitoring QoS that is specified vaguely in SLA could give new insights and implications to web services field. This paper concludes with some recommended future works to construct the theory and perform the empirical research. 相似文献
2.
Ahmad Sadhiqin Mohd Isira Zhengtao Ding 《International journal of systems science》2016,47(16):3772-3781
This paper deals with the leader-follower consensus problem of Lipschitz nonlinear systems under fixed directed communication networks. Both state and output feedback control are proposed based on state and output measurements of neighbouring agents, respectively. Laplacian matrix features are explored for the stability analysis, and the sufficient conditions are derived to solve the consensus problem. Finally, simulation results are included to demonstrate the effectiveness of the output-based consensus controller. 相似文献
3.
The abuse or misuse of antibiotics has caused the emergence of extensively drug-resistant (XDR) bacteria, rendering most antibiotics ineffective and increasing the mortality rate of patients with bacteremia or sepsis. Antimicrobial peptides (AMPs) are proposed to overcome this problem; however, many AMPs have attenuated antimicrobial activities with hemolytic toxicity in blood. Recently, AMPR-11 and its optimized derivative, AMPR-22, were reported to be potential candidates for the treatment of sepsis with a broad spectrum of antimicrobial activity and low hemolytic toxicity. Here, we performed molecular dynamics (MD) simulations to clarify the mechanism of lower hemolytic toxicity and higher efficacy of AMPR-22 at an atomic level. We found four polar residues in AMPR-11 bound to a model mimicking the bacterial inner/outer membranes preferentially over eukaryotic plasma membrane. AMPR-22 whose polar residues were replaced by lysine showed a 2-fold enhanced binding affinity to the bacterial membrane by interacting with bacterial specific lipids (lipid A or cardiolipin) via hydrogen bonds. The MD simulations were confirmed experimentally in models that partially mimic bacteremia conditions in vitro and ex vivo. The present study demonstrates why AMPR-22 showed low hemolytic toxicity and this approach using an MD simulation would be helpful in the development of AMPs. 相似文献
4.
Duk-Shin Lee Tae-Hyun Kim Hana Park Ji-Eun Kim 《International journal of molecular sciences》2022,23(9)
Clasmatodendrosis is one of the irreversible astroglial degeneration, which is involved in seizure duration and its progression in the epileptic hippocampus. Although sustained heat shock protein 25 (HSP25) induction leads to this autophagic astroglial death, dysregulation of mitochondrial dynamics (aberrant mitochondrial elongation) is also involved in the pathogenesis in clasmatodendrosis. However, the underlying molecular mechanisms of accumulation of elongated mitochondria in clasmatodendritic astrocytes are elusive. In the present study, we found that clasmatodendritic astrocytes showed up-regulations of HSP25 expression, AKT serine (S) 473 and dynamin-related protein 1 (DRP1) S637 phosphorylations in the hippocampus of chronic epilepsy rats. 2-Cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid methyl ester (CDDO-Me; bardoxolone methyl or RTA 402) abrogated abnormal mitochondrial elongation by reducing HSP25 upregulation, AKT S473- and DRP1 S637 phosphorylations. Furthermore, HSP25 siRNA and 3-chloroacetyl-indole (3CAI, an AKT inhibitor) abolished AKT-DRP1-mediated mitochondrial elongation and attenuated clasmatodendrosis in CA1 astrocytes. These findings indicate that HSP25-AKT-mediated DRP1 S637 hyper-phosphorylation may lead to aberrant mitochondrial elongation, which may result in autophagic astroglial degeneration. Therefore, our findings suggest that the dysregulation of HSP25-AKT-DRP1-mediated mitochondrial dynamics may play an important role in clasmatodendrosis, which would have implications for the development of novel therapies against various neurological diseases related to astroglial degeneration. 相似文献
5.
6.
Tae Woo Kim Hana Yoo In Young Kim Hyung‐Wook Ha Ah Reum Han Jong‐San Chang Ji Sun Lee Seong‐Ju Hwang 《Advanced functional materials》2011,21(12):2301-2310
Manganese oxide nanocrystals are combined with aluminum oxide nanocrystals to improve their crystallinity via calcination without a significant increase of crystal size. A nanocomposite, consisting of two metal oxides, can be synthesized by the reaction between permanganate anions and aluminum oxyhydroxide keggin cations. The as‐prepared manganese oxide–aluminum oxide nanocomposite is X‐ray amorphous whereas heat‐treatment gives rise to the crystallization of an α‐MnO2 phase at 600 °C and Mn3O4/Mn2O3 and γ‐Al2O3 phases at 800 °C. Electron microscopy and N2 adsorption‐desorption‐isotherm analysis clearly demonstrate that the as‐prepared nanocomposite is composed of a porous assembly of monodisperse primary particles with a size of ~20 nm and a surface area of >410 m2 g?1. Of particular interest is that the small particle size of the as‐prepared nanocomposite is well‐maintained up to 600 °C, a result of the prevention of the growth of manganate grains through nanoscale mixing with alumina grains. The calcined nanocomposite shows very‐high catalytic activity for the oxidation of cyclohexene with an extremely high conversion efficiency of >95% within 15 min. The present results show that the improvement of the crystallinity without significant crystal growth is very crucial for optimizing the catalytic activity of manganese oxide nanocrystals. 相似文献
7.
Pacaiova Hana 《Frontiers of Mechanical Engineering in China》2010,5(2):184-188
Maintenance management requirements have another dimension in the present as in the past. Looking for the optimal tools of decision processing is hard. The current concepts have represented the integration of theoretical, technical, and management tools whose applications need actual modification. Technical measurements are expensive and take a long time/term, and it is hard to estimate the economical returns. This paper presents the concept of a maintenance management task and its function in preventing major accidents. The importance of considering the reliability of maintenance tasks and the method to reach it are also discussed in this paper. 相似文献
8.
Abdul Sathar A. Muneer P. Thafasal Ijyas V. P. Usman Mohammed Shamim Mohammed Zubair M. Shiblee Mohd. 《Wireless Personal Communications》2020,111(2):1129-1150
Wireless Personal Communications - Current research in wireless communication undoubtedly points towards the tremendous advantages of using visible light as a spectrum for significantly boosting... 相似文献
9.
Label‐QoS switching protocol for quality of service assurance in dynamic swarm robot local network 下载免费PDF全文
Addie Irawan Mohd Falfazli Mat Jusoh Mohammad Fadhil Abas 《International Journal of Communication Systems》2018,31(10)
This paper presents the modeling and analysis of a proposed label–quality of service (QoS) switching protocol for heterogeneous robot in a swarm. Establishing the data communication and network in multirobot task allocation is an important aspect in robot collaboration. Instead of passing the data through the cloud network, each robot can be configured as a node in its swarm for intercommunication. This research was conducted to model and propose aggregation and classification methods in a swarm robot network inspired from multiprotocol label switching, namely, label‐QoS switching protocol. Each packet of data is forwarded with a proposed 2‐side label values that are concerned with addressing and QoS. This proposed protocol was applied in each of the node's routing, and it was set up with forwarding information table. The simulation and analysis were conducted in 2 situations: (1) with a constant n–label switch mobile robot and a number of packet data increasing with time and (2) with a constant number of packet and varying n–label switch mobile robot by time. With reference to the network parameter performances, it shows that the anomaly treatment by the proposed protocol is able to prioritize the data forwarding between the robots at the edge of the swarm with class of service although the robot community at the center is increasing or getting crowded. 相似文献
10.
Multidimensional Systems and Signal Processing - The present work is the second article in a couple of intertwined papers. They form complementary items on the same subject. They both address the... 相似文献