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371.
Kernel principal component analysis (kernel PCA) is a non-linear extension of PCA. This study introduces and investigates the use of kernel PCA for novelty detection. Training data are mapped into an infinite-dimensional feature space. In this space, kernel PCA extracts the principal components of the data distribution. The squared distance to the corresponding principal subspace is the measure for novelty. This new method demonstrated a competitive performance on two-dimensional synthetic distributions and on two real-world data sets: handwritten digits and breast-cancer cytology.  相似文献   
372.
Ohne Zusammenfassung Schlu? des Aufsatzes aus Heft 2 (1974) S. 37/46.  相似文献   
373.
This study investigated pubertal changes in neural and behavioral responses to estradiol. Gonadectomized pre- and postpubertal male hamsters (Mesochcetus auratus) were treated with 0.00, 0.05, 0. 10, or 0.2 mg estradiol and tested 1 week later for sexual behavior with a receptive female. Estradiol activated behavior in postpubertal, but not prepubertal, males. In contrast, estrogen receptor α (ERα) and progesterone receptor (PR) immunoreactivity in forebrain nuclei that mediate mating behavior was similar in pre- and postpubertal males. Thus, absence of a behavioral response before puberty is not associated with reduced levels of steroid receptors. Because estradiol induced PR in prepubertal males these data also suggest that ERα is functional before puberty. Therefore, gonadal steroids facilitate male reproductive behavior only after as-yet-unidentified developmental processes occur during puberty. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
374.
For applications in the petrochemical industry, process gas-expanders must be capable of operating at inlet temperatures up to 760°C. The gas contains erosive particles. This contribution is concerned primarily with the design philosophy used by M.A.N.-GHH STERKRADE in manufacturing these machines. Operating experience gathered over a period of 12000 hours is described. During this time, the dust particle loading and size was much more severe than the loading for which the machine was designed. The degree of erosion occurring and modifications made to the machine are described.  相似文献   
375.
We describe a novel framework for specifying and monitoring Service Level Agreements (SLA) for Web Services. SLA monitoring and enforcement become increasingly important in a Web Service environment where enterprise applications and services rely on services that may be subscribed dynamically and on-demand. For economic and practical reasons, we want an automated provisioning process for both the service itself as well as the SLA managment system that measures and monitors the QoS parameters, checks the agreed-upon service levels, and reports violations to the authorized parties involved in the SLA management process. Our approach to these issues is presented in this paper. The Web Service Level Agreement (WSLA) framework is targeted at defining and monitoring SLAs for Web Services. Although WSLA has been designed for a Web Services environment, it is applicable as well to any inter-domain management scenario, such as business process and service management, or the management of networks, systems and applications in general. The WSLA framework consists of a flexible and extensible language based on XML Schema and a runtime architecture comprising several SLA monitoring services, which may be outsourced to third parties to ensure a maximum of objectivity. WSLA enables service customers and providers to unambiguously define a wide variety of SLAs, specify the SLA parameters and the way they are measured, and relate them to managed resource instrumentations. Upon receipt of an SLA specification, the WSLA monitoring services are automatically configured to enforce the SLA. An implementation of the WSLA framework, termed SLA Compliance Monitor, is publicly available as part of the IBM Web Services Toolkit.  相似文献   
376.

This paper presents measurement results of the world wide first successful certification the electrical properties of a wind turbine, solely based upon measurements obtained at a system test bench with HiL-System and grid emulator. For all certification relevant tests the results are compared to field measurements. The impact of the real-time models in the HiL-System as well as the converter-based grid emulator are discussed in this paper. For full converter wind turbine, different requirements for the model depth could be determined depending on the tests. Nevertheless, higher-quality models that reflect the plant behaviour better are recommended to reduce uncertainties within the certification process. This paper also shows that especially for grid failure events grid emulators require real-time impedance control, in order to emulate grid failures properly. Based on these findings, recommendations for the requirements on test bench components are formulated in this paper, in order to contribute to new certification guidelines. Overall, we conclude that based on the experiences made at two different system test benches, the vast majority of certification measurements can be carried out without limitation at such system test benches.

  相似文献   
377.
Nanotheranostics, combining diagnostics and therapy, has the potential to revolutionize treatment of neurological disorders. But one of the major obstacles for treating central nervous system diseases is the blood–brain barrier (BBB) preventing systemic delivery of drugs and optical probes into the brain. To overcome these limitations, nanodiamonds (NDs) are investigated in this study as they are a powerful sensing and imaging platform for various biological applications and possess outstanding stable far‐red fluorescence, do not photobleach, and are highly biocompatible. Herein, fluorescent NDs encapsulated by a customized human serum albumin–based biopolymer (polyethylene glycol) coating (dcHSA‐PEG) are taken up by target brain cells. In vitro BBB models reveal transcytosis and an additional direct cell–cell transport via tunneling nanotubes. Systemic application of dcHSA‐NDs confirms their ability to cross the BBB in a mouse model. Tracking of dcHSA‐NDs is possible at the single cell level and reveals their uptake into neurons and astrocytes in vivo. This study shows for the first time systemic NDs brain delivery and suggests transport mechanisms across the BBB and direct cell–cell transport. Fluorescent NDs are envisioned as traceable transporters for in vivo brain imaging, sensing, and drug delivery.  相似文献   
378.
Our paper describes the requirements and possibilities of integration of metrics tools in the field of software quality assurance. Tools for the support of the measurement process are herein classified as Computer Assisted Software Measurement and Evaulation Tools (CAMETools). Software measurement regarded as a special type of metrics application provides a great amount of basic information for the evaluation of the software development process or the software product itself. Our paper examines the effectiveness and destination of software measurement in tool-based software development and is based on an analysis of more than 20 CAME tools in the Software Measurement Laboratory at the University of Magdeburg. CAMEtools are useable for the process, product, and resources evaluation in all phases of the software life cycle (including the problem definition) for different development paradigms. The efficiency of CAME tools is described on the basis of a general measurement framework. This framework includes all steps in the software measurement and evaulation process: metrics definition, selection of the evaluation criteria, tool-based modelling and measurement, value presentation and statistical analysis. The framework includes the main aspects of the process evaluation techniques (Capability Maturity Model, ISO 9000-3 etc.) and product evaluation (ISO 9126, etc.). It is not a disjointed set of aspects: our measurement framework represents an incremental technique for the application of quantification of quality aspects in a required quality assurance  相似文献   
379.
We report on a systematic study of the magnetoelectric effect in cobalt ferrite (CoFe2O4)—barium titanate (BaTiO3) ceramic composites with (0‐3) connectivity. Both the converse magnetoelectric coefficient, αC, and the direct voltage magnetoelectric coefficient, αE, were measured in dependence on composition and electric and magnetic bias fields. The strongest ME effect was observed in the composition (1?x) CoFe2O4xBaTiO3 with x = 0.5 yielding values αC = 25 psm?1 and αE = 3.2 mV/(cm·Oe). We show that the proper conversion between these two coefficients demands knowledge about the dielectric permittivity of the sample. For low BaTiO3 content the dielectric coefficient of the composite yields a better correspondence, whereas for high BaTiO3 content the sample's average dielectric coefficient yields a better match. The influence of mutual orientation of polarization and magnetization on the ME effect is addressed. We found that for measurements performed parallel to the polarization direction (longitudinal effect), the ME coefficient is approximately twice as large and of opposite sign in comparison to the measurements perpendicular to the polarization direction (transverse effect). This difference has been rationalized in terms of the different contributions of the material coefficient tensor components to the ME effect, the demagnetizing factor, and losses. The obtained results provide a better understanding of peculiarities of the ME effect in bulk ceramic composites.  相似文献   
380.
Biophysical parameters such as leaf area index (LAI) are key variables for vegetation monitoring and particularly important for modelling energy and matter fluxes in the biosphere. Therefore LAI has been derived from remote sensing data operationally based on data with a somewhat coarse spatial resolution. This study aims at deriving high-spatial resolution (6.5 m) multi-temporal LAI for grasslands based on RapidEye data by statistical regressions between vegetation indices (VIs) and field samplings. However, the suitability of those data for grassland LAI derivation has not been tested to date. Thus, the potential of RapidEye data in general and its red edge band in particular are investigated, as well as the robustness of the established relationships for different points in time.

LAI was measured repeatedly over summer 2011 at about 30 different meadows in the Bavarian alpine upland using the LAI-2000 and correlated with VI values. The best relationships resulted from using the ratio vegetation index and red edge indices (NDVIrededge, rededge ratio index 1, and relative length) in non-linear models. Thus the indices based on the red edge channel improved regression modelling. The associated transfer functions achieved R2 values ranging from 0.57 to 0.85. The temporal transferability of those transfer functions to other dates was shown to be limited, with the root mean square errors (RMSEs) of several scenes exceeding one. However, when the LAI ranges are similar, a reliable transfer is possible: for example, the transfer of the regression function based on early autumn measurements showed RMSEs of only 0.77–0.95 for the other scenes except for the high-density stage in July, when the LAI reaches unprecedented maximal values. Also, the combination of multi-temporal training data shows no saturation of the selected indices and enables a satisfactory LAI mapping of different dates (RMSE = 0.59 – 1.02).  相似文献   
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