Energy Storage Likely to Increase in Utility Resource Planning

Today energy storage is a diverse asset class, and technological advances and rapid cost declines have now resulted in a wide array of energy storage technologies increasingly being deployed on utility systems across the country. Utilities from Hawaii to New York have been finding energy storage an extremely attractive and cost-effective way to solve grid needs.     

Tuning the electronic properties of graphene by hydrogenation in a plasma enhanced chemical vapor deposition reactor

Graphene films grown by chemical vapor deposition on copper foils were hydrogenated using commercially viable methods. Parameters such as plasma power, plasma frequency, and sample temperature were varied to determine the maximum possible hydrogenation without etching the film. The kinetic energy of the ions inside the plasma is critical, in that higher kinetic energy ions tend to etch the film while lower kinetic energy ions participate in the hydrogenation process. The film sheet resistance was shown to increase, while the hole mobility was shown to decrease with increasing hydrogenation. Variable temperature measurements demonstrate a transition from semi-metallic behavior for graphene to semiconducting behavior for hydrogenated graphene. Sheet resistance measurements as a function of temperature also suggest the emergence of a bandgap in the hydrogenated graphene films.     

Single limb performance following contralateral bimanual limb training.

Recent studies on intermanual transfer of reaching movements suggest that this transfer is conducted over an "extrinsic" coordinate system. We hypothesize that training reaching movements in a force field with both hands at the same time, in the same position (bimanual grip) will be more beneficial in promoting transfer of the learned skill to the dominant hand than training the unimpaired limb on the same movements in the same force field since the representation of the movement should be invariant of the limb. However, unlike intermanual transfer, bimanual transfer has the potential to involve infinite number of actuator combinations, or joint configurations, interfering with consistent transfer. The efficacy of this method of transfer has implications for people with hemiparesis since the less-affected arm could potentially "instruct" the more-affected arm how to move. Here, we report on an experiment that evaluates and compares the skill transfer between limbs in a reaching task: 1) intermanual transfer (from the nondominant to the dominant hand) and 2) bimanual transfer (from a bimanual grip to the dominant hand) with healthy subjects. We used two methods from which to judge the transfer: performance in the presence of the force field or by errors made during "catch trials" when the forces were unexpectedly removed as subjects changed hands (known as after effects of adaptation). We found only a small amount of transfer (20% of that seen in the practiced limb) with both types of training, and surprisingly there was no significant difference in the movement accuracy between these two training methods. Moreover, the direction of the after effects supports the assertion that the nervous system generalizes these movements in an extrinsic coordinate system. Accordingly, the limb must experience the dynamics singularly in order to develop an internal model.     

Signal detection in power-law noise: effect of spectrum exponents

Many natural backgrounds have approximately isotropic power spectra of the power-law form, P(f)=K/f(beta), where f is radial frequency. For natural scenes and mammograms, the values of the exponent, beta, range from 1.5 to 3.5. The ideal observer model predicts that for signals with certain properties and backgrounds that can be treated as random noise, a plot of log (contrast threshold) versus log (signal size) will be linear with slope, m, given by: m=(beta-2)/2. This plot is referred to as a contrast-detail (CD) diagram. It is interesting that this predicts a detection threshold that is independent of signal size for beta equal to 2. We present two-alternative forced-choice (2AFC) detection results for human and channelized model observers of a simple signal in filtered noise with exponents from 1.5 to 3.5. The CD diagram results are in good agreement with the prediction of this equation.     

Modelling a complex supply chain: understanding the effect of simplified assumptions

The benefits of coordinating activities and consolidating distribution points in supply chains are well highlighted and intuitively logical. However, the impact of these decisions on the overall performance of a complex supply chain may not be as obvious as usually perceived. This study models a relatively complex supply chain and evaluates the impact of simplifying demand and lead time assumptions under various supply chain configurations. Of particular interest is the investigation of the effect of risk pooling and the synchronization of production cycles in a multi-level multi-retailer supply chain under the influence of various parameters such as batch size, delivery frequency and ordering cycle. This study highlights the extent of complicated interaction effects among various factors exist in a complex supply chain and shows that that the intricacy of these effects can be better understood with a simulation model.     

Grating light reflection spectroscopy for determination of bulk refractive index and absorbance

An optical sensing technique is described and evaluated for sensitivity to changes in refractive index and absorbance of model sample matrices. A binary dielectric/metal transmission diffraction grating is placed in contact with a sample and utilized in reflection mode; thus, the light captured and analyzed does not pass through the sample. This particular condition creates thresholds at which a particular transmitted diffraction order is transformed from a traveling wave to an evanescent one. The positions of these thresholds depend upon the complex dielectric function of the sample, the period of the grating, and the wavelength and incident angle of light striking the grating. Experimental evidence directly supports the theoretical predictions regarding responses to both the real and imaginary portions of the refractive index: the reflection coefficient derivative wavelength peak position shifts linearly with changes in the real part of the refractive index, and the derivative peak amplitudes exhibit a square-root dependence on absorbance. Refractive index sensitivity to a series of ethanol/water solutions is demonstrated with detectable changes in index as small as 2 × 10(-)(6). Absorbance sensitivity is shown via the differentiation of methylene blue samples having equivalent 1 cm path length absorbances between 0.459 and 244 AU. In a single reflection measurement, GLRS offers a large dynamic range for absorbance detection, allows simultaneous determination of bulk refractive index in optically dense media, and provides a platform for performing continuous process analysis.     

Early development of spiny neurons in fish and mouse: morphometric measures of dendritic spine formation pattern

Positions of spines on apical dendrites were evaluated using 4 pattern analysis techniques: spine counts, variance/mean ratio, Lloyd's patchiness index, and nearest neighbor distance matrix. Spiny tectal interneurons from jewel fish (100, 130, 160 and 1550 days old), and layer V pyramidal cells in layer IV auditory cortex of CBA/J mice (100 and 450 days old) were studied. Fish's spines became more numerous and more clumped on distal dendritic strata during development, while mice lost dendritic spines with age. Both species developed a significantly regular spacing pattern between neighboring spines during development. These changes are explained in the context of spine function and a biophysical model of dendritic spine patterns.     

Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukaemia cells predict a poor response to chemotherapy and reduced patient survival

We investigated the role of the drug resistance-related proteins LRP, MRP and Pgp and the apoptotic suppressor, bcl-2, in relation to other clinical characteristics, with respect to response and survival in 91 patients with newly diagnosed AML, treated with standard chemotherapy. Multivariate analysis showed that poor response to chemotherapy was associated with increasing age (P=0.0004), LRP expression (P=0.0001) and Pgp function (P=0.015). The significant predictors of both leukaemia-free survival (LFS) and overall survival (OS) were LRP (LFS, P=0.01; OS, P=0.0001), Pgp function (LFS, P=0.0001; OS, P=0.0003) and cytogenetic abnormalities (LFS, P=0.0001; OS. P=0.0005). Patients with the lowest expression of LRP and Pgp function and favourable karyotype (group I) had an LFS of 30.2 months compared to 8 5 months in the group with the highest expression of LRP and Pgp and poor prognosis karyotype (group III, P=0.002). OS decreased from 75.4 months in group I to 7.9 months in group III patients (P <0.0001). Neither MRP nor bcl-2 were significantly associated with chemotherapy response and survival. Correlations were found between increasing expression of LRP and older age (P=0.05) and an unfavourable karyotype (P=0.005), but these variables were independent of each other in analysis of treatment response and patient survival. Our findings suggest that both LRP and Pgp are clinically relevant drug-resistance proteins and it may be necessary to modulate both LRP and Pgp functions in order to reverse the multidrug resistance phenotype in AML.     

Memory for serial order: A network model of the phonological loop and its timing.

A connectionist model of human short-term memory is presented that extends the "phonological loop" (A. D. Baddeley, see record 1986-98526-000) to encompass serial order and learning. Psychological and neuropsychological data motivate separate layers of lexical, timing, and input and output phonemic information. Connection weights between layers show Hebbian learning and decay over short and long time scales. At recall, the timing signal is rerun, phonemic information feeds back from output to input, and lexical nodes compete to be selected. The selected node then receives decaying inhibition. The model provides an explanatory mechanism for the phonological loop and for the effects of serial position, presentation modality, lexicality, grouping, and Hebb repetition. It makes new psychological and neuropsychological predictions and is a starting point for understanding the role of the phonological loop in vocabulary acquisition and for interpreting data from functional neuroimaging. (PsycINFO Database Record (c) 2010 APA, all rights reserved)