Design and implementation of a web-based medical drawing management system

This paper addresses the architecture and implementation of a medical drawing management system. The system enables physicians to draw directly on a patient picture or built-in anatomical templates of a body part. It contains modules for querying patient data and managing associated drawings including sketching, uploading, and sharing features. The system adapts to embed Windows-based applications into web pages; the web-based applications contain Windows-based graphical tools and enable seamlessly incorporating necessary drawing modules into the web-based healthcare information system at National Taiwan University Hospital. The system provides a web-based sketching capability that effectively support practitioners’ daily operations, as well as the use of paperless, digitizing patient records, and ultimately, will improve the overall quality of healthcare.     

Experimental and computational studies of bulk polymerization of styrene in the presence of N-(O-(1-phenylmethyl)oxy) phthalimide or cyclohexanone-O-(1-phenylmethyl)oxime

Summary Syntheses of potential initiators N-(O-(1-phenylethyl)oxy)phthalimide, N-(O-(1-phenylmethyl)oxy)phthalimide (POP), cyclohexanone-O-(1-phenylethyl)oxime, and cyclohexanone-O-(1-phenylmethyl)oxime (CHPO) are described. Bulk polymerization of styrene in the presence of POP or CHPO and molecular weight measurement by GPC indicate that the polymerization is not a living process. Ab initio calculations show that the C-O or O-N bond cleavage energies of POP and CHPO are close to each other (3: C-O: 46.4, O-N: 47.3 kcal/mol; 1: C-O: 46.9, O-N: 63.0 kcal/mol) and much higher than the similar analogs of 2,2,6,6-tetramethylpiperidinyloxy (TEMPO) (C-O: 20.9, O-N: 34.4 kcal/mol). The similar C-O and O-N bond cleavage energies of the synthesized initiators (POP/CHPO) indicate two possible cleavage pathways and may explain the non-living nature of the polymerization. These results may be helpful in finding future reversible terminator compounds for living polymerization. Received: 28 August 2000/Revised version: 5 December 2000/Accepted: 7 December 2000     

Introduction of affinity set and its application in data-mining example of delayed diagnosis

At least 44,000 people die in hospitals each year as a result of medical errors, and these deaths are becoming the eighth-leading cause of death in the United States. Thus, medical providers have the responsibility to pay attention for reducing avoidable medical errors and improve patient safety as best as they can. It requires the rapid evaluation and prioritisation of life threatening injuries in the primary survey followed by a detailed secondary survey in the emergency room. However, time is always valuable and limited such that some important vital signs may be delayed and ignored. This research explores delayed diagnosis problem and uses the affinity set by Topology concept to classify/focus on key attributes causing delayed diagnosis (missed injury) in order to reduce error risk. Results interestingly indicate that when a patient can breathe normally, but his (or her) blood-pressure or pulse is abnormal, a high probability of delayed diagnosis exists. This affinity work also compares the performance with the model of rough set (Rosetta), neural network, support vector machine and logistic regression. And our affinity model shows its advantage by prediction accuracy and explanation power.     

Preparation and characterization of methoxy‐poly(ethylene glycol) side chain grafted onto chitosan as a wound dressing film

Chitosan has received extensive attention as a biomedical material; however, the poor solubility of chitosan is the major limiting factor in its utilization. In this study, chitosan‐based biomaterials with improved aqueous solubility were synthesized. Two molecular weights (750 Da and 2000 Da) of methoxypoly(ethylene glycol) (mPEG) were grafted onto chitosan (mPEG‐g‐chitosan) to form a ～100‐μm‐thick plastic film as a wound dressing. The chemical structures of the mPEG‐g‐chitosan copolymers were confirmed using Fourier transform infrared spectroscopy (FTIR), and the thermal properties were characterized using thermogravimetry analysis (TGA). Their microstructures were observed using scanning electron microscopy (SEM). The other properties were analyzed via the swelling ratio, tensile strength, elongation, and water vapor transmission rate (WVTR). Biocompatibility evaluations through biodegradability, cytotoxicity, and antimicrobial effect studies were also performed. The obtained mPEG‐g‐chitosan copolymers were soluble in slightly acidic aqueous solutions (pH～6.5) at a concentration of 10 wt %. The optimal mPEG‐g‐chitosan hydrogels had swelling ratios greater than 100% and WVTRs greater than 2000 g/m²/day. Their performance against Staphylococcus aureus will be subjected to further improvements with respect to medical applications. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 42340.     

Predictive maintenance of abnormal wind turbine events by using machine learning based on condition monitoring for anomaly detection

Journal of Mechanical Science and Technology - The predictive maintenance of wind turbines has become a critical issue with the rapid development of wind power generation. The early detection of...     

Maximum entropy probability distributions for flood frequency analysis

It is customary to assume a frequency distribution in flood frequency analysis. The parameters of the distribution are estimated by using observed or transformed data. The fitted distribution is then used to estimate the magnitudes of floods of different frequencies.

The maximum entropy (ME) probability distribution is defined as the 'minimally prejudiced probability distribution which maximizes the entropy subject to constraints supplied by the given information'. In spite of many attractive features of the ME distribution, it has not been used in its general form in practice. The main reason for not using the ME distribution in its general form is that the parameter estimation problem associated with the ME distribution is not easy. Recently this problem has been solved and an algorithm has been developed to estimate the parameters of the ME distribution.

The objective of the research reported in the present paper is to fit ME distributions to flood data. The ME distributions are compared with other well known distributions. The computational aspects and selection of orders of distributions are also discussed. The ME distribution is shown to be versatile and fits a variety of flood data very well.     

Efficient Dispersants for TiO2 Nanopowder in Organic Suspensions

This article discusses the appropriate dispersant for titania (TiO₂) nanopowder in organic‐based suspensions. Four types of oleyl‐based dispersants, namely, oleyl alcohol, oleic acid, oleylamine, and oleyl phosphate, which have the functional groups hydroxyl (–OH), carboxyl (–COOH), amino (–NH₂), and phosphorous [–P(=O)(OH)₂], respectively, were compared for their ability to disperse TiO₂. Experimental results for zeta potential, adsorption, FT‐IR spectroscopy, and rheology, as well as theoretical calculations, indicate that dispersants with –P(=O)(OH)₂ and –NH₂ were more efficient than those with –COOH or –OH. The primary reason for this difference is related to the different interactions of TiO₂ with various dispersants and to different dispersion mechanisms. In addition to the major functional groups, –OH in the chemical structure of dispersants was important, as it might have other effects such as destabilization of the suspensions.     

Thermoplastic polyvinyl alcohol/multiwalled carbon nanotube composites: Preparation,mechanical properties,thermal properties,and electromagnetic shielding effectiveness

This study uses the solution mixing method to combine plasticized polyvinyl alcohol (PVA) as a matrix, and multiwalled carbon nanotubes (MWCNTs) as reinforcement to form PVA/MWCNTs films. The films are then laminated and hot pressed to create PVA/MWCNTs composites. The control group of PVA/MWCNTs composites is made by incorporating the melt compounding method. Diverse properties of PVA/MWCNTs composites are then evaluated. For the experimental group, the incorporation of MWCNTs improves the glass transition temperature (T_g), crystallization temperature, T_c), and thermal stability of the composites. In addition, the test results indicate that composites containing 1.5 wt % of MWCNTs have the maximum tensile strength of 51.1 MPa, whereas composites containing 2 wt % MWCNTs have the optimal electrical conductivity of 2.4 S/cm, and electromagnetic shielding effectiveness (EMI SE) of ?31.41 dB. This study proves that the solution mixing method outperforms the melt compounding method in terms of mechanical properties, dispersion, melting and crystallization behaviors, thermal stability, and EMI SE. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 43474.     

Unusual exfoliation of layered silicate clays by non-aqueous amine diffusion mechanism

The organic ionic exchange intercalation of smectite clays is conventionally performed in water swelling conditions. Here we report a different mechanism for modifying the smectite clays in alcohol solvents. The modification of sodium montmorillonite with poly(oxyethylene-oxypropylene)-amines (POA-amine) were compared for the differences between in water and in alcohol. In water, the intercalation of hydrophobic poly(oxypropylene)-rich amines in the silicate galleries expands the interlayer spacing up to 10 nm and even to exfoliation (featureless in X-ray diffraction pattern) with over 5 amine equivalents, where as hydrophilic poly(oxyethylene)-rich amines could only intercalate in a low spacing of 1.8 nm. On the other hand, all of the POA-amines in isopropanol afford the exfoliation with over, 3 amine equivalents. The mechanism of this unexpected exfoliation is explained by the thermodynamic formations of an imaginary membrane surrounding the clay units, followed by amine diffusion from the solvent into the clay galleries.     

Preparation and characterization of poly(lactic acid)/recycled polypropylene blends with and without the coupling agent,n-(6-aminohexyl)aminomethyltriethoxysilane

Blends of polylactide (PLA) and recycled polypropylene (rPP) were prepared by melt-processing using a corotating twin-screw extruder and subsequent pelletizing of the extrudates for injection molding. The PLA/rPP blends were characterized by Thermogravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC), Dynamic Mechanical Analysis (DMA), rheometer (MCR-102), scanning electron microscopy(SEM), tensile tests, and impact measurements. The results indicate that the PLA/rPP blend is immiscible and has a two-phase structure. TGA revealed enhancement of the thermal stability of the blends upon addition of rPP. The storage modulus, loss modulus, and complex viscosity of the blends increased with rPP concentration. Mechanical studies showed that introduction of rPP results in a decrease in tensile strength and modulus and enhancement of the impact strength of PLA in the blends. The effects of a silane coupling agent on the morphology and on the tensile and impact properties of the rPP blends of silane-modified PLA were also examined. SEM studies suggest that silane is an effective interfacial modifier. Thus, better interfacial adhesion was observed with silane-modified blends as compared with unmodified blends. Silane also improved the mechanical properties of the modified blends. The blends reached maximum tensile strength at 1.5 wt.% silane (relative to modified PLA content), and impact strength increased with increasing silane concentration. These results confirm the enhancing effect of silane on modified PLA/rPP blends.