Experimental study of kerosene–water two‐phase flow in a vertical pipe using hot‐film and dual optical probes

The local parameters for kerosene–water upward flow are measured in a vertical pipe of 77.8 mm inner diameter at 4200 mm from the inlet (L/D = 54) using hot‐film and dual optical probes. The effect of superficial water velocity and volumetric quality on radial distribution of two‐phase flow parameters is investigated. The results show the following: (i) the profiles of volume fraction and drop frequency are very similar, and increasing superficial water velocity at low volumetric qualities (<18.6%) change the profile from a convex shape with peak at the pipe centreline to uniform then to concave shape with peak near the wall; (ii) the profiles of drop cut chord change from a parabolic shape with peak at centreline for low superficial water velocities to a flat shape at higher superficial water velocity, and the area‐averaged drop diameter decreases with higher superficial water velocities for all volumetric qualities; (iii) velocity profiles for both phases have shapes similar to single phase flow, flatter at higher values of superficial water velocity and volumetric quality and centreline peaked at low superficial water velocities and volumetric qualities; (iv) the slip velocity decreases with radial distance having a peak at centreline and zero values near the wall; (v) introducing kerosene drops into single phase water flow results in a sharp increase in turbulent intensity, particularly at low water velocity, and the difference between the single phase and two‐phase flow turbulence intensities decreases with higher superficial water velocities and (vi) the results show that interfacial area concentration increased with higher volumetric quality and higher number of bubbles thereby increases the contact area between the two phases. © 2012 Canadian Society for Chemical Engineering     

Antioxidative activity of summer savory (Satureja hortensis L.) and rosemary (Rosmarinus officinalis L.) in minced, cooked pork meat

The sensory intensity measured as theabsolute threshold value of spice andrecognition of spice was evaluated for summer savory and rosemary in meat balls. The values forabsolute threshold value of spice were found to be significantly lower for rosemary than for summer savory. The antioxidative activity of the spices was analysed in two accelerated model systems and in a storage experiment. In one of the model systems, oxidation was accelerated by heat and by an elevated pressure of oxygen. Both spices significantly improved the oxidative stability of the meat balls in this model system. In the second model system metal catalyst oxidation in a meat slurry was used and a reduction in the oxidative processes in samples containing the spices was again shown. In both model systems a slightly higher antioxidative activity was seen for rosemary compared to summer savory. In the storage experiment, the spices were added at a sensorially acceptable level and the heat-treated meat balls were stored at 5°C. A significant reduction in the development of warmed-over flavour (WOF) caused by the addition of spices was measured by a reduction in 2-thiobarbituricacid-reactivesubstances (TBARS) and in hexanal. A reduction in TBARS of approximately 30% in meat balls containing added spices was seen independently of packaging in 1% oxygen or in atmospheric air and the reduction (30%) was constant throughout the storage period.     

Amlodipine dynamic effects and myocardial pharmacokinetics in the isolated and perfused guinea-pig heart

Myocardial dynamic effects and pharmacokinetics of amlodipine were studied in the isolated retrogradely perfused and spontaneously beating guinea-pig heart. Pharmacokinetic analysis of drug accumulation showed one-compartment characteristics with an half-life of 76 min. Whereas disposition exhibited two-compartment characteristics with phasic half-lives of 25 and 174 min., respectively. Myocardial drug accumulation was increased by 600 times at steady-state compared to the perfusion liquid. Dynamic effect parameters were studied during increasing amlodipine concentrations from 0.16 to 220 nM. Dynamic steady-states developed within 20 min. Coronary flow-rate increased with an Emax of 119% and an EC50 of 1.2 x 10(-8) M. Amlodipine produced inhibitory effects on contraction amplitude and velocities of contraction and relaxation. Observed Emax-values and curve-fitted EC50-values were: 97, 97 and 94% and 1.10(-8), 7.7 x 10(-9) and 2.1 x 10(-8) M, respectively. Heart frequency was not changed. Oxygen consumption increased markedly to a maximum of 44% at 3 x 10(-8) M amlodipine and then decreased to nearly initial values. The frequency-corrected QT-interval decreased to a maximal extent of 20% at the three highest concentrations. Myocardial efficiency expressed as the ratio of contraction velocity times frequency to oxygen consumption exhibited a progressive decline to about 2% of initial values. The PQ-interval was not changed and the QRS-interval showed only a small but significant decrease at the highest amlodipine concentration. No arrythmogenic effects were observed. The study demonstrated a very slow accumulation and disposition of amlodipine in the guinea-pig heart with a steady-state myocardial drug concentrating accumulation of 600 times. Marked increase in coronary flow-rate and oxygen consumption accompanied by a progressive negative inotropic effect were observed.     

Electronic properties of gallium-arsenide field-effect-transistor structure used as detector for acoustic surface waves

A GaAs field-effect-transistor structure has been used as a detector for acoustic surface waves in the frequency range 65?200 MHz. The conversion loss is shown to be strongly dependent on the source-gate and source-drain voltages. The minimum value obtained is 26 dB for frequencies between 80 and 150 MHz.     

Affective same-different discrimination tests for assessing consumer discriminability between milks with subtle differences

Affective and analytical same-different discrimination tests for assessing the ability of consumers to discriminate between milks with subtle differences were designed by applying familiarization procedures to induce an affective/synthetic and analytical/synthetic perceptual strategy. The tests were then administered to 100 milk consumers and compared. In both same-different discriminations, consumers adopted a cognitive decision rule that used a β-strategy rather than a τ-strategy. Discrimination tests employing an affective/synthetic perceptual approach (which is the normal consumer perceptual process) resulted in higher discriminability than tests that employed an analytical/synthetic approach. Inter-individual differences in the consumer criteria (boundaries) used for same-different ratings were studied by examining the response distributions over the given response categories for the same pairs. According to the similarity of such response distributions, two different consumer segments were classified and their group discriminabilities differed significantly, with only the more sensitive group showing interactions between the affective/hedonic state and perceptual discriminability.     

Measuring the coolness of interactive products: the COOL questionnaire

Coolness has recently started to be explored as a design goal for interactive products from practitioners as well as researchers within human–computer interaction (HCI), but there is still a need to further operationalise the concept and explore how we can measure it. Our contribution in this paper is the COOL questionnaire. We based the creation of the questionnaire on literature suggesting that perceived coolness is decomposed to outer cool (the style of a product) and inner cool (the personality characteristics assigned to it). In this paper, we focused on inner cool, and we identified 11 inner cool characteristics. These were used to create an initial pool of question items and 2236 participants were asked to assess 16 mobile devices. By performing exploratory and confirmatory factor analyses, we identified three factors that can measure the perceived inner coolness of interactive products: desirability, rebelliousness and usability. These factors and their underlying 16 question items comprise the COOL questionnaire. The whole process of creating the questionnaire is presented in detail in this paper and we conclude by discussing our work against related work on coolness and HCI.     

The Wireless Nursing Call System: Politics of Discourse, Technology and Dependability in a Pilot Project

This paper discusses a research project in which social scientists were involved both as analysts and supporters during a pilot with a new wireless nursing call system. The case thus exemplifies an attempt to participate in developing dependable health care systems and offers insight into the challenges of developing and supporting such systems. The analysis proposes that while dependability is not simply a technical issue, neither is it something, which can be improved merely by adding a social dimension. Instead, it argues that dependability is a relative concept, which may mean different things conditional on how it is specified in practice and who gets to do this. This relativity makes it important to relate the question of how to support dependable health care systems to an analysis of both the politics of technology within specific projects and to the politics of discourse, through which the researcher becomes involved in such projects.     

Interpolating by a factor of 3 in low-voltage low-power ΣΔ DAC

This paper presents the power optimization of a sigma-delta (ΣΔ) modulator based digital-to-analog converter (DAC) for hearing aid audio back-end application. In a number of state-of-the-art publications the oversampling ratio (OSR) of the ΣΔ modulator is chosen as a factor of integer power of two. The reason given is the simplicity of the interpolation filter (IF). However, being able to choose OSR factors of integer powers of two only, might be restricting and not necessarily optimal. Therefore the ΣΔ modulator based DAC designs with multistage IF that include a stage performing oversampling by a factor of 3 are investigated. This new design freedom is used to lower the operating frequency of the whole back-end and save considerable amount of power. It is shown that the figure-of-merit of such designs can be lower than designs using oversampling by a factor of integer powers of two. The same optimization approach can be used for other low voltage low power portable audio applications (mobile phones, notebook computers etc.).     

Tiron Has Negative Effects on Osteogenic Differentiation via Mitochondrial Dysfunction in Human Periosteum-Derived Cells

Tiron is a potent antioxidant that counters the pathological effects of reactive oxygen species (ROS) production due to oxidative stress in various cell types. We examined the effects of tiron on mitochondrial function and osteoblastic differentiation in human periosteum-derived cells (hPDCs). Tiron increased mitochondrial activity and decreased senescence-associated β-galactosidase activity in hPDCs; however, it had a detrimental effect on osteoblastic differentiation by reducing alkaline phosphatase (ALP) activity and alizarin red-positive mineralization, regardless of H₂O₂ treatment. Osteoblast-differentiating hPDCs displayed increased ROS production compared with non-differentiating hPDCs, and treatment with tiron reduced ROS production in the differentiating cells. Antioxidants decreased the rates of oxygen consumption and ATP production, which are increased in hPDCs during osteoblastic differentiation. In addition, treatment with tiron reduced the levels of most mitochondrial proteins, which are increased in hPDCs during culture in osteogenic induction medium. These results suggest that tiron exerts negative effects on the osteoblastic differentiation of hPDCs by causing mitochondrial dysfunction.