Internalized homophobia and relationship quality among lesbians, gay men, and bisexuals.

The authors examined the associations between internalized homophobia, outness, community connectedness, depressive symptoms, and relationship quality among a diverse community sample of 396 lesbian, gay, and bisexual (LGB) individuals. Structural equation models showed that internalized homophobia was associated with greater relationship problems both generally and among coupled participants independent of outness and community connectedness. Depressive symptoms mediated the association between internalized homophobia and relationship problems. This study improves present understandings of the association between internalized homophobia and relationship quality by distinguishing between the effects of the core construct of internalized homophobia and its correlates and outcomes. The findings are useful for counselors interested in interventions and treatment approaches to help LGB individuals cope with internalized homophobia and relationship problems. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Conductivity Measurement Using Four Linear Electrodes Embedded Inside a Rectangular Sample

Using solid materials prepared by melting or sintering allows inert metal electrodes to be embedded inside the solid. The I–V relations for four linear electrodes embedded inside a rectangular sample are evaluated. Two cases are considered: (a) a sample with uniform electronic (electron/hole) conductivity and (b) the electron/hole partial current in a sample that is a mixed ionic-electronic conductor with a nonuniform electron/hole distribution. Equations are derived which allow the determination of the conductivity from four-electrode measurements if a pure electronic conductor is considered or if a mixed ionic-electronic conductor is considered with the ionic current being blocked.     

The interconnections between socio-spatial factors and labour market integration among Arabs in Israel

The current study investigated labour market integration of Arabs in Israel using Schnell et al.'s ( 2015 ) global segregation/integration index (GSI) that assesses minorities’ socio-spatial integration in multi-ethnic contexts. The merit of this approach lies in being multifaceted and systematically incorporating socio-spatial spheres. The study also conducted structured interviews with the respondents (n = 142), and employed GPS loggers to track their weekly movements. GSI socio-spatial indicators emerged significantly associated with integration in the labour market, with movement in space being the prominent. The study signifies the socio-spatial approach's application to the study of minorities’ labour market integration in metropolitan areas.     

"After Me,The Deluge": Uncertainty and Water Policy in Israel

Israel's water system is characterized by a very high degree of uncertainty, emanating from the semi-arid climatic position, and the dynamic population growth.The agricultural sector dominates water policy making, thereby giving preference to the sector that consumes roughly 70% of the available resources. Water for agriculture is priced too low, resulting in its inefficient use. This paper seeks to explain water policy making in Israel, as an attempt to cope with uncertainty. We show that the pattern has been to shift the burden of uncertainty from present consumers to future consumers. This pattern is explained by the following factors: the high vulnerability of Israel's water system, due to uncertainty in both supply and demand; the inclination of elected policy makers to give preference to short-term objectives over long-term objectives; the acceptance of uncertainty as a constraint rather than a policy variable; and the acceptance of a given level of agricultural activity as a permanent constraint.     

Transthoracic approach for removing adrenal masses

Early results with the transthoracic approach for removing adrenal tumors were evaluated. Between May 1994 and December 1995, 8 women and 5 men (aged 18-74) with adrenal masses underwent transthoracic adrenalectomy. All were excised successfully with short operation times (mean: 86 min), minimal blood loss (151 ml), limited use of parenteral analgesics (1.3 days), early ambulation (1.7 days post operation) and a short period of parenteral nutrition (1.7 days), resulting in reduced hospital stay (mean 6.7 days). With the transthoracic approach procedures are quick and safe even for large, malignant, and hormone-producing tumors. Recovery is easy with brief hospitalization. It provides excellent exposure of the adrenals, enables good control of bleeding vessels and is therefore our preferred method for removing adrenal masses.     

Feasibility study of parameter estimation of random sampling jitter using the bispectrum

An actual sampling process can be modeled as a random process, which consists of the regular (uniform) deterministic sampling process plus an error in the sampling times which constitutes a zero-mean noise (the jitter). In this paper we discuss the problem of estimating the jitter process. By assuming that the jitter process is an i.i.d. one, with standard deviation that is small compared to the regular sampling time, we show that the variance of the jitter process can be estimated from thenth order spectrum of the sampled data,n=2, 3, i.e., the jitter variance can be extracted from the 2nd-order spectrum or the 3rd-order spectrum (the bispectrum) of the sampled data, provided the continuous signal spectrum is known. However when the signal skewness exceeds a certain level, the potential performance of the bispectrum-based estimation is better than that of the spectrum-based estimation. Moreover, the former can also provide jitter variance estimates when the continuous signal spectrum is unknown while the latter cannot. This suggests that the bispectrum of the sampled data is potentially better for estimating any parameter of the sampling jitter process, once the signal skewness is sufficiently large.     

Insulin and C-peptide (proinsulin) packaging: A quantitative immunocytochemical approach

C-peptide and insulin antigenic sites in rat pancreatic β cells were both labeled by the protein A and immunogold techniques. Gold bead density in the secretory granules was correlated with granule size distribution. Our results demonstrate that the distribution patterns of antigenic sites for C-peptide (which also represents proinsulin sites) and insulin are similar when granule size distribution is correlated to the density of antigenic sites. It was found that the ratio of C-peptide to insulin in granules is independent of granule size. Examination of frequency histograms by a Kolmogorov-Smirnov analysis excluded the possibility that the antigenic sites of C-peptide and insulin are distributed in the same manner. Mean gold bead density for insulin antigen (97 ± 24) was slightly higher than C-peptide density (64 ± 18). The efficiency of labeling was found to be very low; less than 0.1% of the theoretically estimated antigenic sites were labeled.     

Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats

Recombinant adenoviruses are highly efficient at transferring foreign genes in vivo. However, duration of gene expression is limited by the host antiviral immune response which precludes expression upon viral readministration. We tested the feasibility of prolonging gene expression by induction of central tolerance to adenoviral antigens in bilirubin-UDP-glucuronosyltransferase-1 (BUGT1)-deficient Gunn rats. Tolerance was induced by intraperitoneal injection of antilymphocyte serum, followed by intrathymic inoculation of one of the following: a recombinant adenovirus (Ad), adenovirus human UDP-glucuronosyltransferase (Ad-hBUGT1) carrying the hBUGT1 gene; a protein extract of the same virus; or viral infected hepatocytes. Controls received intrathymic injections of normal saline. After 12 d all groups were injected intravenously with 5 x 10(9) pfu of either Ad-hBUGT1 or adenovirus beta-galactosidase (Ad-LacZ) (expressing the Escherichia coli beta-galactosidase [LacZ] gene). In all three groups of tolerized rats, hBUGT1 was expressed in the liver after administration of Ad-hBUGT1, with glucuronidation of biliary bilirubin of above 95%. Serum bilirubin levels decreased from 7.2 to 1.8 mg/dl within 1 wk and remained low for 7 wk. Similar findings were observed following repeat injections given on days 45 and 112. In control rats serum bilirubin levels were reduced for only 4 wk, and viral readministration was ineffective. In all tolerized groups, but not in controls, there was a marked inhibition of appearance of neutralizing antibodies and cytotoxic lymphocytes against the recombinant adenovirus. Injection of wild type adenovirus-5 (Ad5) into the tolerized rats elicited a wild type-specific cytotoxic lymphocyte response. This is the first demonstration of Ad-directed long-term correction of an inherited metabolic disease following central tolerization with thymic antigen.     

A geometric view of parametric linear programming

We present a new definition of optimality intervals for the parametric right-hand side linear programming (parametric RHS LP) Problem () = min{c ^t x¦Ax =b + ¯b,x 0}. We then show that an optimality interval consists either of a breakpoint or the open interval between two consecutive breakpoints of the continuous piecewise linear convex function (). As a consequence, the optimality intervals form a partition of the closed interval {; ¦()¦ < }. Based on these optimality intervals, we also introduce an algorithm for solving the parametric RHS LP problem which requires an LP solver as a subroutine. If a polynomial-time LP solver is used to implement this subroutine, we obtain a substantial improvement on the complexity of those parametric RHS LP instances which exhibit degeneracy. When the number of breakpoints of () is polynomial in terms of the size of the parametric problem, we show that the latter can be solved in polynomial time.This research was partially funded by the United States Navy-Office of Naval Research under Contract N00014-87-K-0202. Its financial support is gratefully acknowledged.