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11.
The goal of the study was to determine the influence of drying shrinkage on the kinetics of convection apple slab drying. The arbitrary Lagrange-Eulerian (ALE) method was used to enter a problem with moving boundaries. It was found that drying shrinkage had a major influence on the both simulated temperature and water content in the material. The lower the moisture content in particles during drying, the more pronounced the effect of shrinkage on simulation of heat and mass transfer. It was found that application of the arbitrary Lagrange-Eulerian method for shrinkage modeling leads to a relatively simple mathematical model of the drying kinetics of shrinkable materials. 相似文献
12.
Statistical tests were applied to determine the effects of temperature, moisture content, density, and porosity of material on the effective moisture diffusion coefficient during convective drying of root celery. In biological materials with colloidal capillary-porous structure (like root celery), which shrink considerably during drying and show high heterogeneity, the effective water diffusion coefficient depends not only on material temperature and moisture content, but also on its density. It was found that statistical tests can be applied to predict which independent variables should describe the water diffusivity in colloidal capillary-porous materials. A mathematical model of the effective water diffusion coefficient in root celery was formulated as Arhenius-type equation with moisture content of the raw material, its temperature and density as independent variables. 相似文献
13.
Jacek Chroscielewski Zbigniew Cywinski Ireneusz Kreja Stanislaw Uminski 《Computers & Structures》1983,17(1):37-44
Computer aided finite element analysis has been applied to evaluate the structural behavior of a solid plate representing statically certain box-type construction of a dry dock gate. Possible comparison of particular results following from different procedures, valid for constant plate stiffness and rigid supports, has been performed and the distribution of reactions for variable plate stiffness, within two different numerical accuracies, has been studied. For practical requirements the nonlinear elastic flexibility of dock gate packing has been taken into account and an adequate numerical step-by-step approach, satisfying the considered material characteristics, developed. For last case the deflections, reactions, and internal forces have been examined in detail and a comparison with those for rigid supports presented. 相似文献
14.
The paper is focused on identifying error sources in computational fluid dynamics(CFD) predictions of a spray drying process. Seven groups of drying and atomisation parameters were selected for analysis and 13 simulation trials were performed. The theoretical results were compared with experimental data and sensitivity of the simulation results to the analysed factors was determined. The following parameters affecting the accuracy of CFD spray modelling were found: gas turbulence model, particle dispersion, atomising air, initial parameters of atomisation and heat losses to the environment. A major difference in the errors committed during modelling of spray drying process for fine and coarse sprays was observed. 相似文献
15.
Ireneusz Szcześniak Tadeusz Czachórski Jean-Michel Fourneau 《Photonic Network Communications》2008,16(3):253-261
We present an approximate analytical method for the evaluation of packet loss probability in synchronous optical packet-switched
networks which operate under limited deflection routing with the contention resolution method based on priorities. Packets
are lost because they are removed by nodes. They are removed because they experience too many deflections and stay prohibitively
long in the network. Such packets have to be removed because they will be ignored by the transmission protocols (like TCP)
and because the quality of their optical signal is unacceptable. Presented are results for the network in the topology of
the torus of the two-dimensional grid, which operates at a steady state with the uniform load u, . The strength of our analysis is its novel mathematical approach, which is capable of providing very low packet loss probabilities.
For the network composed of 100 nodes, we predict the packet loss probability as low as 10−9 or lower, while simulation provided results only at the order of 10−6. For a given permissible packet loss probability, our analysis provides the maximal network load and the number of allowed
deflections. We verify the analysis with simulation in the cases for which simulation gave results.
相似文献
Jean-Michel FourneauEmail: |
16.
Ireneusz Litwin Seweryn Mucha Ewa Pilarczyk Robert Wysocki Ewa Maciaszczyk-Dziubinska 《International journal of molecular sciences》2021,22(9)
Antimony is a toxic metalloid with poorly understood mechanisms of toxicity and uncertain carcinogenic properties. By using a combination of genetic, biochemical and DNA damage assays, we investigated the genotoxic potential of trivalent antimony in the model organism Saccharomyces cerevisiae. We found that low doses of Sb(III) generate various forms of DNA damage including replication and topoisomerase I-dependent DNA lesions as well as oxidative stress and replication-independent DNA breaks accompanied by activation of DNA damage checkpoints and formation of recombination repair centers. At higher concentrations of Sb(III), moderately increased oxidative DNA damage is also observed. Consistently, base excision, DNA damage tolerance and homologous recombination repair pathways contribute to Sb(III) tolerance. In addition, we provided evidence suggesting that Sb(III) causes telomere dysfunction. Finally, we showed that Sb(III) negatively effects repair of double-strand DNA breaks and distorts actin and microtubule cytoskeleton. In sum, our results indicate that Sb(III) exhibits a significant genotoxic activity in budding yeast. 相似文献
17.
Monika K. Nisiewicz Agata Kowalczyk Anna Sobiepanek Agata Jagielska Barbara Wagner Julita Nowakowska Marianna Gniadek Ireneusz P. Grudzinski Tomasz Kobiela Anna M. Nowicka 《International journal of molecular sciences》2021,22(1)
Nearly half of patients with advanced and metastatic melanomas harbor a BRAF mutation. Vemurafenib (VEM), a BRAF inhibitor, is used to treat such patients, however, responses to VEM are very short-lived due to intrinsic, adaptive and/or acquired resistance. In this context, we present the action of the B-Raf serine-threonine protein kinase inhibitor (vemurafenib) on the glycans structure and metallomics profiles in melanoma cells without (MeWo) and with (G-361) BRAF mutations. The studies were performed using α1-acid glycoprotein (AGP), a well-known acute-phase protein, and concanavalin A (Con A), which served as the model receptor. The detection of changes in the structure of glycans can be successfully carried out based on the frequency shifts and the charge transfer resistance after interaction of AGP with Con A in different VEM treatments using QCM-D and EIS measurements. These changes were also proved based on the cell ultrastructure examined by TEM and SEM. The LA-ICP-MS studies provided details on the metallomics profile in melanoma cells treated with and without VEM. The studies evidence that vemurafenib modifies the glycans structures and metallomics profile in melanoma cells harboring BRAF mutation that can be further implied in the resistance phenomenon. Therefore, our data opens a new avenue for further studies in the short-term addressing novel targets that hopefully can be used to improve the therapeutic regiment in advanced melanoma patients. The innovating potential of this study is fully credible and has a real impact on the global patient society suffering from advanced and metastatic melanomas. 相似文献
18.
Paweł Wawrzyniak Maciej Jaskulski Ireneusz Zbiciński Marek Podyma 《Advanced Powder Technology》2017,28(1):167-176
A methodology is presented here for the mathematical modelling of moisture evaporation in a dispersed system in an industrial tower. An empirical model using characteristic drying curves was applied to calculate moisture evaporation from a droplet and particle. A simple method was developed to calculate the agglomeration process of the dispersed phase in the drying towers, using transient functions between the initial and final particle size distributions, at the nozzle and in the final product. The developed model and simulation results were validated on the basis of industrial spray tower experiments. High instability of the airflow due to the geometry of the dryer and the construction of the air inlets was observed. The general methodology applied within this CFD model is universal, and can be applied to the scaling-up of installations for dewatering in dispersed systems in order to determine configurations of feeding systems and control the product quality and safety of the process. 相似文献
19.
Roman Klimkiewicz Helena Teterycz Hanna Grabowska Ireneusz Morawski Ludwik Syper Benedykt W. Licznerski 《Journal of the American Oil Chemists' Society》2001,78(5):533-535
A mixture of methyl esters of fatty acids obtained by transterification of nonerucic rape oil was ketonized. The starting
material, diluted with methanol, was converted at atmospheric pressure over a catalyst that contained Sn, Ce, and Rh oxides
in a molar ratio of 90:9:1. At a temperature of 385°C ketones were obtained with a total yield of 63% at the 96% conversion
of starting material. The reported experiments prove that catalysts other than iron that are active in ketonization of primary
alcohols can be successfully used in ketonization of esters of fatty acids. The kind of diluent used plays a crucial role
in the conversion. 相似文献
20.
Czeslaw Strumillo Ireneusz Zbici
ski Iwona Smucerowicz Clayton Crowe 《Chemical Engineering and Processing: Process Intensification》1999,38(4-6):593-600
The paper presents a theoretical and experimental analysis of a pulse combustion spray drying system. Measurements of the velocity flow field inside the drying chamber and extensive tests on drying and water evaporation were carried out for various feed rates and operating parameters of the pulse combustor. Each test included the analysis of temperature distribution in the dryer, evaporation level and sprayed material structure. LDA and PDA techniques were employed to determine the character of pulsating flow in the chamber, amount of water evaporated and to perform a profound analysis of spray structure. Experimental results show an intensive and efficient drying process. An attempt was made to perform theoretical predictions of velocity and temperature distribution in the drying chamber. The CFD technique was used to calculate time-dependent flow in the chamber. Results show vanishing velocity, pressure and temperature oscillations along the length of the drying chamber. Temperature oscillations decline faster than oscillations of pressure and velocity. Satisfactory agreement between calculations and experimental results was found in certain regions of the drying chamber. Discrepancies might be caused by simplification of the system geometry and flow pattern which were assumed to perform calculations in reasonable time. 相似文献