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81.
Karel Domansky Josiah D. Sliz Norman Wen Christopher Hinojosa Guy ThompsonII Jacob P. Fraser Tiama Hamkins-Indik Geraldine A. Hamilton Daniel Levner Donald E. Ingber 《Microfluidics and nanofluidics》2017,21(6):107
The majority of microfluidic devices used for cell culture, including Organ-on-a-Chips (Organ Chips), are fabricated using polydimethylsiloxane (PDMS) polymer because it is flexible, optically clear, and easy to mold. However, PDMS possesses significant challenges for high volume manufacturing and its tendency to absorb small hydrophobic compounds limits its usefulness as a material in devices used for drug evaluation studies. Here, we demonstrate that a subset of optically clear, elastomeric, styrenic block copolymers based on styrene-ethylene-butylene-styrene exhibit reduced absorption of small hydrophobic molecules and drug compounds compared to PDMS and that they can be fabricated into microfluidic devices with fine features and the flexibility required for Organ Chips using mass production techniques of injection molding and extrusion. 相似文献
82.
Ingve Simonsen Jacob B. Kryvi Alexei A. Maradudin Tamara A. Leskova 《Computer Physics Communications》2011,182(9):1904-1908
An approach is introduced for performing rigorous numerical simulations of electromagnetic wave scattering from randomly rough, perfectly conducting surfaces. It is based on a surface integral technique, and consists of determining the unknown electric surface current densities from which the electromagnetic field everywhere can be determined. The method is used to study the scattering of a p-polarized beam from an anisotropic Gaussian, randomly rough, perfectly conducting surface. It is demonstrated that the surface anisotropy gives rise to interesting and pronounced signatures in the angular intensity distribution of the scattered light. The origins of these features are discussed. 相似文献
83.
Daniel Welfer Jacob Scharcanski Diane Ruschel Marinho 《Computer methods and programs in biomedicine》2011,104(3):397-409
In this work, we present a new fovea center detection method for color eye fundus images. This method is based on known anatomical constraints on the relative locations of retina structures, and mathematical morphology. The detection of this anatomical feature is a prerequisite for the computer aided diagnosis of several retinal diseases, such as Diabetic Macular Edema. The proposed method is adaptive to local illumination changes, and it is robust to local disturbances introduced by pathologies in digital color eye fundus images (e.g. exudates). Our experimental results using the DRIVE image database indicate that our method is able to detect the fovea center in 37 out of 37 images (i.e. with a success rate of 100%). Using the DIARETDB1 database, our method was able to detect the fovea center in 92.13% of all tested cases (i.e. in 82 out of 89 images). These results indicate that our approach potentially can achieve a better performance than comparable methods proposed in the literature. 相似文献
84.
85.
Behavioral detection differs from appearance detection in that it identifies the actions performed by the malware rather than
syntactic markers. Identifying these malicious actions and interpreting their final purpose is a complex reasoning process.
This paper draws up a survey of the different reasoning techniques deployed among the behavioral detectors. These detectors
have been classified according to a new taxonomy introduced inside the paper. Strongly inspired from the domain of program
testing, this taxonomy divides the behavioral detectors into two main families: simulation-based and formal detectors. Inside
these families, ramifications are then derived according to the data collection mechanisms the data interpretation, the adopted
model and its generation, and the decision support. 相似文献
86.
At the 1992 AAAI robot contest one of the top finishers was Scarecrow—a robot that had no computer in the traditional sense,
was built out of less than $200 of parts, and was explained and operated by a five year old. The designers sought to demonstrate
the capabilities and competence that can be accomplished by using a strictly reactive architecture for well defined tasks
such as that contest. This paper reexamines the Scarecrow robot and puts it into historical context. With fifteen years of
perspective, we can also see what Scarecrow has to say about the perception of intelligence.
相似文献
David P. MillerEmail: |
87.
88.
Mixture model for face-color modeling and segmentation 总被引:11,自引:0,他引:11
In this paper, we propose a general methodology for face-color modeling and segmentation. One of the major difficulties in face detection and retrieval is partial face extraction due to highlights, shadows and lighting variations. We show that a mixture-of-Gaussians modeling of the color space, provides a robust representation that can accommodate large color variations, as well as highlights and shadows. Our method enables to segment within-face regions, and associate semantic meaning to them, and provides statistical analysis and evaluation of the dominant variability within a given archive. 相似文献
89.
K. T. Jacob 《Journal of Materials Science》1980,15(9):2167-2174
The phase diagram of the Cr-W-O system at 1000° C was established by metallographic and X-ray identification of the phases present after equilibration in evacuated silica capsules. Two ternary oxide phases, CrWO4 and Cr2WO6 were detected. The oxygen potential over the three-phase mixtures, W+Cr2O3 s+CrWO4, WO2.90+CrWO4+Cr2WO6 and Cr2O3+CrWO4+Cr2WO6, were measured by solid state cells incorporating Y2O3 stabilized ZrO2 electrolyte and Ni+NiO reference electrode. The Gibbs' energies of formation of the two ternary phases can be represented by the following equations $$\begin{gathered} W(s) + \tfrac{1}{2} Cr_2 O_3 (s) + \tfrac{5}{4} O_2 (g) \to CrWO_4 (s) \hfill \\ \Delta G^0 = - 172 047 + 48.725T ( \pm 230) cal mol^{ - 1} \hfill \\ Cr_2 O_3 (s) + WO_3 (s) \to Cr_2 WO_6 (s) \hfill \\ \Delta G^0 = - 3 835 + 0.235{\rm T} ( \pm 500) cal mol^{ - 1} \hfill \\ \end{gathered}$$ 相似文献
90.
Xiaozhen Mou Jisha Jacob Xinxin Lu Steven Robbins Shulei Sun Joseph D. Ortiz 《Journal of Great Lakes research》2013
Studies on the bacterial communities in Lake Erie have been largely focused on cyanobacteria. To characterize the community structure of the other bacteria, we examined the 16S rRNA gene content of free-living (FL) and particle-associated (PA) bacterioplankton populations in Sandusky Bay (SD) and adjacent waters in the Western Basin (WB) of Lake Erie. A comprehensive survey of nutrients and other limnological variables was also performed in parallel. A total of 18,569 of 16S rRNA V6 pyrotag sequences were recovered, which were affiliated with 64 unique bacterial orders within 14 phyla. FL bacteria were composed differently from PA ones and contained significantly more Actinomycetales. In addition, FL bacteria were taxonomically more diverse. Despite the distinct environmental conditions, compositional variation was insignificant between bacteria in the SD and WB samples. 相似文献