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31.
Wash Ivanovic Glen 《建筑学研究前沿(英文版)》2014,3(1):36-43
The present research introduces the Activity Counter Maps (ACM) as a methodology for visualizing people's social spaces, arguing that accurate representations of these spaces are crucial for understanding the role of human activity as a place-making coordinate. The ACM were tested in two case studies conducted in Ueno Park (Tokyo). The first case study is focused on the visualization of the intensity of activity in the totality of the park. The second case study is focused in two sub-places of the park, generating representations of people's personal spaces combined into a three-dimensional “Common social space”. The research concludes with the analysis of the generated visualizations and their potential for incorporating place-variables into the digital design process. 相似文献
32.
Ljiljana Radovanovic Jelena Petrovic Jasna Saponjic 《International journal of molecular sciences》2021,22(16)
We investigated the alterations of hippocampal and reticulo-thalamic (RT) GABAergic parvalbumin (PV) interneurons and their synaptic re-organizations underlying the prodromal local sleep disorders in the distinct rat models of Parkinson’s disease (PD). We demonstrated for the first time that REM sleep is a predisposing state for the high-voltage sleep spindles (HVS) induction in all experimental models of PD, particularly during hippocampal REM sleep in the hemiparkinsonian models. There were the opposite underlying alterations of the hippocampal and RT GABAergic PV+ interneurons along with the distinct MAP2 and PSD-95 expressions. Whereas the PD cholinopathy enhanced the number of PV+ interneurons and suppressed the MAP2/PSD-95 expression, the hemiparkinsonism with PD cholinopathy reduced the number of PV+ interneurons and enhanced the MAP2/PSD-95 expression in the hippocampus. Whereas the PD cholinopathy did not alter PV+ interneurons but partially enhanced MAP2 and suppressed PSD-95 expression remotely in the RT, the hemiparkinsonism with PD cholinopathy reduced the PV+ interneurons, enhanced MAP2, and did not change PSD-95 expression remotely in the RT. Our study demonstrates for the first time an important regulatory role of the hippocampal and RT GABAergic PV+ interneurons and the synaptic protein dynamic alterations in the distinct rat models of PD neuropathology. 相似文献
33.
The quality of crystals depends on many factors that determine their granulometric properties. In order to obtain crystals of desired size distribution, proper selection of the operating conditions is of a great importance. Commonly, the unseeded cooling crystallization is controlled by selecting the appropriate cooling profile. The crystallization process can also be controlled by adding a certain number of seed crystals of a uniform size in the crystallizer at the saturation temperature. This paper investigates the influence of the process conditions (mixing intensity, cooling profile, batch time, saturation temperature and seeding) on the granulometric properties of pentaerythritol obtained by batch cooling crystallization. All investigated process conditions influence the crystal size distribution (seeded and unseeded experiments). On the other hand, the shape of crystals was the same for all experimental conditions. Optimal cooling profile, lower retention time, higher mixing rate, and smaller initial seed surface area improves the final crystal size distribution. 相似文献
34.
Tumbas VT Canadanović-Brunet JM Cetojević-Simin DD Cetković GS Ethilas SM Gille L 《Journal of the science of food and agriculture》2012,92(6):1273-1281
BACKGROUND: The commercial development of plants as sources of antioxidants that can be used to enhance the properties of foods, for nutritional purposes and preservation as well as for prevention of oxidation‐related diseases, is currently of major interest. Rosehip (Rosa canina L.) is a rich source of vitamin C and polyphenols. RESULTS: Phytochemicals in rosehip tea were separated into three fractions: Fr1 (vitamin C, 39.17 mg kg?1), Fr2 (flavonoids, 451.05 µg kg?1) and Fr3 (phenolic acids, 504.69 µg kg?1). Quercetin and ellagic acid were the most abundant polyphenolic compounds. Rosehip fractions, primarily rosehip flavonoids (EC50 = 49 mg L?1), showed high antioxidant activity towards 2,2‐diphenyl‐1‐picrylhydrazyl radicals (DPPH?). Cell growth effects of rosehip fractions were assessed in HeLa, MCF7 and HT‐29 cell lines, with the lowest IC50 values being determined for rosehip flavonoids, (80.63, 248.03 and 363.95 mg L?1 respectively). However, the vitamin C fraction did not inhibit the growth of tested tumour cells. CONCLUSION: The results of this study confirm that vitamin C and flavonoids are responsible for the antioxidant activity of rosehip tea, while only polyphenols contribute to its antiproliferative activity. Copyright © 2011 Society of Chemical Industry 相似文献
35.
Jelena Vulić Jasna Čanadanović-Brunet Gordana Ćetković Vesna Tumbas Sonja Djilas Dragana Četojević-Simin Vladimir Čanadanović 《Journal of Functional Foods》2012,4(3):670-678
Beetroot (Beta vulgaris) pomace, processing by-product from food industry, was investigated in this work as a starting raw material. The contents of phenolics (1.87–11.98 mg GAE/g of dry weight) and betalains (0.75–3.75 mg betalains/g of dry weight) in the extracts were determinated spectrophotometrically. Some individual phenolic compounds, including ferulic, vanillic, p-hydroxybenzoic, caffeic and protocatehuic acids, were identified and quantified by HPLC. The antioxidative activity of beetroot extracts was tested using DPPH, hydroxyl and superoxide anion radicals by ESR spectroscopy. (0.05–0.108 mg/ml), (0.183–0.333 mg/ml), and (0.198–1.000 mg/ml) were calculated. The regression analysis produced moderate to high correlation coefficients between the scavenging activities and phenolics, and some individual phenolic compounds which indicated that beetroot pomace may be used as functional food ingredient. Cell growth effects were determined in MCF7 and MRC-5 cell lines, using SRB assay. IC50 values were in the range of 362.478–503.525 and 383–587.880 μg/ml in MRC-5 and MCF7, respectively. 相似文献
36.
Evaluation of the phenolic content,antioxidant activity and colour of Slovenian honey 总被引:1,自引:0,他引:1
Honey samples from the seven most common honey types in Slovenia were screened for total phenolic content by the modified Folin–Ciocalteu method, for potential antioxidant activity using the ferric reducing antioxidant power (FRAP) assay and by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method for antiradical activity. In addition the colour characteristics of honey samples were analysed. The results of the study showed that total phenolic content, antioxidant activity and colour parameters differ widely among different honey types. Phenolic content expressed as gallic acid equivalent ranged from 44.8 mg/kg in acacia honey to 241.4 mg/kg in fir honey. Antioxidant activity was the lowest in the brightest acacia and lime honeys and the highest in darker honeys, namely fir, spruce and forest. The colour of the Slovenian honeys, analysed in this study was very variable and ranged from pale yellow to dark brown. Correlations between the parameters analysed were found to be statistically significant (p < 0.05). 相似文献
37.
Marija V. Pergal Vesna V. Antić Milutin N. Govedarica Dejan Goäevac Sanja Ostojić Jasna Djonlagić 《应用聚合物科学杂志》2011,122(4):2715-2730
Novel polyurethane copolymers derived from 4,4′‐methylenediphenyl diisocyanate (MDI), 1,4‐butanediol (BD) and α,ω‐dihydroxy‐[poly(caprolactone)‐poly (dimethylsiloxane)‐poly(caprolactone)] (α,ω‐dihydroxy‐(PCL‐PDMS‐PCL); = 6100 g mol?1) were synthesized by a two‐step polyaddition reaction in solution. In the synthesis of the polyurethanes, the PCL blocks served as a compatibilizer between the nonpolar PDMS blocks and the polar comonomers, MDI and BD. The synthesis of thermoplastic polyurethanes (TPU) with high soft segment contents was optimized in terms of the concentrations of the reactants, the molar ratio of the NCO/OH groups, and the time and temperature of the polyaddition reaction. The structure, composition, and hard MDI/BD segment length of the synthesized polyurethane copolymers were determined by 1H, 13C‐NMR, and two‐dimensional correlation (COSY, HSQC, and HMBC) spectroscopy, while the hydrogen bonding interactions in the copolymers were analyzed by FT‐IR spectroscopy. The influence of the reaction conditions on the structure, molecular weight, thermal, and some physical properties was studied at constant composition of the reaction mixture. A change in the molar ratio of the NCO/OH groups and the reaction conditions modified not only the molecular weight of the synthesized polyurethanes, but also the microstructure and therefore the thermal and physical properties of the copolymers. It was demonstrated that only PCL segments with high soft segment contents crystallize, thereby showing spherulitic morphology. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011 相似文献
38.
A. Starkey A. Ivanovic R. D. Neilson A. A. Rodger 《Advances in Engineering Software》2003,34(11-12):753-761
The GRANIT1 system is a non-destructive integrity testing method for ground anchorages. It has won two major UK Awards—the Design Council Millennium Product Status in 1999 and the John Logie Baird Award in 1997. It makes use of novel artificial intelligence techniques in order to learn the complicated relationship that exists between an anchorage and its frequency response to an impulse. The GRANIT system has a worldwide patent and is currently licensed to AMEC plc.It is widely recognised that non-destructive testing methods for ground anchorages need to be developed as a high priority [A National Agenda for Long-term and Fundamental Research for Civil Engineering in the United Kingdom (1992)], with only between 1 and 5% of anchorages currently being monitored in service [British Standard Code of Practice for Ground Anchorages (8081) (1989)] using currently available techniques. The GRANIT system is a solution for this requirement, and this paper describes how the use of artificial intelligence techniques enabled, for the first time, the cross-anchorage diagnosis of ground anchorages, where data taken from one anchorage was used to train a neural network, which was then used to diagnose the condition of an adjacent anchorage.The results presented in this paper describe the training of a neural network on data taken from a bolt anchorage, and the diagnosis, using this neural network, of further test data taken from the same anchorage. Data taken from an adjacent anchorage of similar construction is also presented to the neural network, and the cross-anchorage diagnosis of the load level of the second anchorage is achieved. 相似文献
39.
Ivan S. Stefanović Jasna V. Džunuzović Enis S. Džunuzović Danijela V. Randjelović 《应用聚合物科学杂志》2024,141(8):e54989
The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings. 相似文献
40.
Duško Minić Jelena Đokić Vladan Ćosović Jasna Stajić-Trošić Dragana Živković Irma Dervišević 《Materials Chemistry and Physics》2010
Phase diagram of the ternary Bi–Sb–Zn system was investigated experimentally by DTA and SEM-EDS methods and analytically by CALPHAD method. The liquidus projection, invariant equilibria, several vertical sections and isothermal section at 300 °C were predicted using COST 531 thermodynamic database. Phase transition temperatures of alloys along three predicted vertical sections of the Bi–Sb–Zn ternary system with molar ratio Bi:Sb = 1, Bi:Zn = 1 and Sb:Zn = 1, were measured by differential thermal analysis (DTA). Predicted isothermal section at 300 °C was compared with the results of the scanning electron microscope (SEM) with energy dispersive spectrometry (EDS) analysis from this work. 相似文献