全文获取类型
收费全文 | 4059篇 |
免费 | 437篇 |
国内免费 | 10篇 |
专业分类
电工技术 | 58篇 |
化学工业 | 1163篇 |
金属工艺 | 152篇 |
机械仪表 | 231篇 |
建筑科学 | 75篇 |
能源动力 | 241篇 |
轻工业 | 358篇 |
水利工程 | 10篇 |
石油天然气 | 4篇 |
无线电 | 757篇 |
一般工业技术 | 950篇 |
冶金工业 | 120篇 |
原子能技术 | 75篇 |
自动化技术 | 312篇 |
出版年
2024年 | 3篇 |
2023年 | 52篇 |
2022年 | 76篇 |
2021年 | 134篇 |
2020年 | 108篇 |
2019年 | 127篇 |
2018年 | 149篇 |
2017年 | 182篇 |
2016年 | 172篇 |
2015年 | 168篇 |
2014年 | 216篇 |
2013年 | 296篇 |
2012年 | 325篇 |
2011年 | 412篇 |
2010年 | 248篇 |
2009年 | 268篇 |
2008年 | 191篇 |
2007年 | 160篇 |
2006年 | 138篇 |
2005年 | 129篇 |
2004年 | 107篇 |
2003年 | 127篇 |
2002年 | 97篇 |
2001年 | 101篇 |
2000年 | 80篇 |
1999年 | 72篇 |
1998年 | 64篇 |
1997年 | 39篇 |
1996年 | 40篇 |
1995年 | 34篇 |
1994年 | 31篇 |
1993年 | 16篇 |
1992年 | 20篇 |
1991年 | 18篇 |
1990年 | 17篇 |
1989年 | 18篇 |
1988年 | 12篇 |
1987年 | 10篇 |
1986年 | 15篇 |
1985年 | 10篇 |
1984年 | 9篇 |
1983年 | 1篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 3篇 |
1976年 | 2篇 |
1975年 | 1篇 |
1974年 | 1篇 |
排序方式: 共有4506条查询结果,搜索用时 15 毫秒
31.
Sung Kyung Hong Sang Cheol Leev Jae Won Han Young-sun Ryuh 《International Journal of Control, Automation and Systems》2012,10(5):1000-1004
To achieve the goal of low-cost MEMS gyros for the precise self-localization of mobile robots, this paper presents a simple, yet effective method to minimize drifts on the heading angle by combining measurements from a gyro with measurements from wheel encoders (odometry). The main idea of the proposed approach is to estimate the accuracy of both sensors as a function of the actual maneuver being carried out, and then the output of both sensors are fused by the complementary filter taking into account the maneuvering conditions. The proposed method is applied to a mobile robot and the experimental data demonstrate the effectiveness of this approach. 相似文献
32.
33.
34.
Min?-Ho?LeeEmail author Dong?-Joo?Yoon Dae?-Hee?Won Tae?-Sung?Bae Fumio?Watari 《Metals and Materials International》2003,9(1):35-42
In the present study, commercial pure Ti and Ti-6Al-4V alloy specimens with and without alkali and heat treatments were implanted
in the abdominal connective tissue of mice. Conventional stainless steel 316L was also implanted for comparison. After three
months, their biocompatibility was evaluated byin vitro andin vivo experiments. Surface structural changes of specimens due to the alkali treatment and soaking in Hank’s solution were analyzed
by XRD, SEM, XPS and AES. An apatite layer, which accelerates the connection with bone, was formed more easily on the alkali
treated specimens than the non-treated specimens. The number of macrophages, which is known to increase as the inflammatory
reaction proceeds, was much lower for the alkali and heat treated specimens than for the others. The average thickness of
the fibrous capsule formed around the implant was much thinner for the alkali and heat treated specimens than for the others. 相似文献
35.
Youri Oh Hoyong Jung Hyejin Kim Jihyun Baek Joonhong Jun Hyunwook Cho Daseul Im Jung-Mi Hah 《International journal of molecular sciences》2021,22(8)
Polo-like kinase 1 (PLK1) plays an important role in cell cycle progression and proliferation in cancer cells. PLK1 also contributes to anticancer drug resistance and is a valuable target in anticancer therapeutics. To identify additional effective PLK1 inhibitors, we performed QSAR studies of two series of known PLK1 inhibitors and proposed a new structure based on a hybridized 3D-QSAR model. Given the hybridized 3D-QSAR models, we designed and synthesized 4-benzyloxy-1-(2-arylaminopyridin-4-yl)-1H-pyrazole-3-carboxamides, and we inspected its inhibitory activities to identify novel PLK1 inhibitors with decent potency and selectivity. 相似文献
36.
Cheol Park Won Sup Lee Se-Il Go Sang-Ho Jeong Jiyun Yoo Hee-Jae Cha Young-Joon Lee Heui-Soo Kim Sun-Hee Leem Hye Jung Kim Gon Sup Kim Soon-Chan Hong Yung Hyun Choi 《International journal of molecular sciences》2021,22(6)
Evidence suggests that augmented expression of a certain gene can influence the efficacy of targeted and conventional chemotherapies. Here, we tested whether the high expression of enhancer of the rudimentary homolog (ERH), which serves as a prognostic factor in some cancers, can influence the efficacy of anthocyanins isolated from fruits of Vitis coignetiae Pulliat, Meoru in Korea (AIMs) on human gastric cancer cells. The anticancer efficacy of AIMs was augmented in ERH-transfected MKN28 cells (E-MKN28 cells). Molecularly, ERH augmented AIM-induced caspase-dependent apoptosis by activating caspase-3 and -9. The ERH-augmented apoptotic effect was related to mitochondrial depolarization and inhibition of antiapoptotic proteins, XIAP, and Bcl-2. In addition, reactive oxygen species (ROS) generation was augmented in AIMs-treated E-MKN28 cells compared to AIMs-treated naïve MKN28 cells. In conclusion, ERH augmented AIM-induced caspase-dependent mitochondrial-related apoptosis in MKN28 cells. A decrease in expression of Bcl-2 and subsequent excessive ROS generation would be the mechanism for ERH-augmented mitochondrial-related apoptosis in AIMs-treated MKN28 cells. A decrease in expression of XIAP would be another mechanism for ERH-augmented caspase-dependent apoptosis in AIMs-treated MKN28 cells. 相似文献
37.
Nipin Sp Dong Young Kang Jin-Moo Lee Se Won Bae Kyoung-Jin Jang 《International journal of molecular sciences》2021,22(9)
Hormone-specific anticancer drugs for breast cancer treatment can cause serious side effects. Thus, treatment with natural compounds has been considered a better approach as this minimizes side effects and has multiple targets. 6-Gingerol is an active polyphenol in ginger with various modalities, including anticancer activity, although its mechanism of action remains unknown. Increases in the level of reactive oxygen species (ROS) can lead to DNA damage and the induction of DNA damage response (DDR) mechanism, leading to cell cycle arrest apoptosis and tumorsphere suppression. Epidermal growth factor receptor (EGFR) promotes tumor growth by stimulating signaling of downstream targets that in turn activates tumor protein 53 (p53) to promote apoptosis. Here we assessed the effect of 6-gingerol treatment on MDA-MB-231 and MCF-7 breast cancer cell lines. 6-Gingerol induced cellular and mitochondrial ROS that elevated DDR through ataxia-telangiectasia mutated and p53 activation. 6-Gingerol also induced G0/G1 cell cycle arrest and mitochondrial apoptosis by mediating the BAX/BCL-2 ratio and release of cytochrome c. It also exhibited a suppression ability of tumorsphere formation in breast cancer cells. EGFR/Src/STAT3 signaling was also determined to be responsible for p53 activation and that 6-gingerol induced p53-dependent intrinsic apoptosis in breast cancer cells. Therefore, 6-gingerol may be used as a candidate drug against hormone-dependent breast cancer cells. 相似文献
38.
39.
The formation of a phase pure silicon ingot from SiO2+Al+KClO3 and Na2SiO3+Al+KClO3 systems was investigated thermodynamically and experimentally under combustion mode, known also as self-propagating high-temperature
synthesis (SHS). The regularities of combustion and phase formation versus KClO3 concentration by a thermocouple technique were obtained. The morphology, chemical and phase composition of the silicon ingot
were analyzed by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), and ICP-analysis. The method reported
here proved effective in producing silicon ingots with a purity of 98%. 相似文献
40.
A new aromatic diamine monomer containing benzoxazole substituents was prepared by a multistep synthesis starting from 1,4‐dibromo‐2,5‐difluorobenzene. The diamine was polymerized with commercial aromatic dianhydride or dicarboxylic acid chloride monomers to provide several different poly(amic acid)s and polyamides with their inherent viscosities in the range of 0.24–0.46 dL/g. Thermal properties of these polymers including thermal imidization of poly(amic acid)s into polyimides were investigated by using FTIR, DSC, and TGA. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 92: 178–185, 2004 相似文献