Environmental models are often over-parameterized. A sensitivity analysis can identify influential model parameters for, e.g. the parameter estimation process, model development, research prioritization and so on. This paper presents the results of an extensive study of the Latin-Hypercube-One-factor-At-a-Time (LH-OAT) procedure applied to the Soil and Water Assessment Tool (SWAT). The LH-OAT is a sensitivity analysis method that can be categorized as a screening method. The results of the sensitivity analyses for all output variables indicate that the SWAT model of the river Kleine Nete is mainly sensitive to flow related parameters. Rarely, water quality parameters get a high priority ranking. It is observed that the number of intervals used for the Latin-Hypercube sampling should be sufficiently high to achieve converged parameter rankings. Additionally, it is noted that the LH-OAT method can enhance the understanding of the model, e.g. on the use of water quality input data. 相似文献
Chemical cues, such as volatile organic compounds (VOCs), are often essential for insects to locate food. Relative to the volume of studies on the role of VOCs in insect-plant relationships, the role of VOCs emitted by dung and carrion in mediating the behavior of insect decomposers is understudied. Such relationships may provide a mechanistic understanding of the temporal axis of community assembly processes in decomposing insect communities. We focused on the temporal succession of volatiles released by cow dung pats and the potential influence on dung-inhabiting insects. Using gas chromatography/mass spectrometry we identified and quantified VOCs released from dung 1-h, and 1, 2 3, 5, and 7 d-old. We then related changes in VOCs to successional patterns of dung-inhabiting beetles and flies. We detected 54 VOCs which could be assigned to two successional groups, with chemical turnover in dung changing around day 2. The early successional group consisted primarily of aliphatic alcohols and phenols, and the late one of aliphatic esters, nitrogen- and sulfur-bearing compounds. Flies were predominately associated with the early successional group, mainly with 1-butanol. Beetles were associated predominately with the late-successional group, mainly with dimethyl trisulfide. This association between insect and chemical successional patterns supports the idea that habitat filtering drives the community assembly of dung-inhabiting insects on an aging resource. Moreover, the affinity of both insect groups to specific VOC groups provides a mechanistic explanation for the predictability of successional patterns found in dung-inhabiting insect communities.
Journal of Porous Materials - In this study, the production of porous carbon fibers from viscose fibers was investigated. The effects of final carbonization temperature... 相似文献
We present experimental results and numerical simulations of multiple-wavelength conversion of 10 Gb/s non-return-to-zero (NRZ) signals based on 2-pumps four-wave mixing and of 40Gb/s return-to-zero (RZ) signals through supercontinuum (SC) generation in a highly nonlinear fiber (HNLF). Two pumps with a 100 GHz separation located in the region of anomalous dispersion of the HNLF were combined to form a beat signal The 10 Gb/s NRZ signal anchored on ITU grid was converted with gain into 6 new signals and 6 idlers with 100 GHz separation. High quality sc with bandwidth exceeding 50 nm was generated when the HNLF was pumped with 25 dBm average power. Sliced sc can be used as a source for all-optical multicasting. 相似文献
We present a comparative review of Evolutionary Algorithms that generate new population members by sampling a probability distributionconstructed during the optimization process. We present a unifying formulation for five such algorithms that enables us to characterize them based on the parametrization of the probability distribution, the learning methodology, and the use of historical information.The algorithms are evaluated on a number of test functions in order to assess their relative strengths and weaknesses. This comparative reviewhelps to identify areas of applicability for the algorithms and to guidefuture algorithmic developments. 相似文献
A two-stage, distribution-planning problem is addressed. Customers are to be served with different commodities from a number of plants, through a number of intermediate distribution centres (DCs). The possible locations for the DCs are given. For each location, there is a fixed cost for opening the DC concerned, as well as an operating cost and a maximum capacity. The demand of each customer for each commodity is known, as well as shipping costs throughout. There are also two additional important requirements. First, each customer must be served with all the products it requires from a single distribution centre. Secondly, it must be possible to ascertain the plant origin of each product quantity delivered. The objective is to choose the locations for opening DCs such that the total cost is minimised. The problem is modelled as a mixed-integer-programming problem and solved by branch and bound. Lower bounds are calculated through a series of structural transformations. Much of the power of the solution scheme also stems from frequent generation of good upper bounds. Results of extensive computational experiments are given and discussed. 相似文献
A broad protease-based and cell-based screening of protease inhibitors yielded the aziridine-2-carboxylic acid derivative 2 a and the N-acylated aziridine-2,3-dicarboxylic acid derivatives 32 a and 34 b as the most potent inhibitors of falcipain-2 and falcipain-3 (IC(50) falcipain-2: 0.079-5.4 microM, falcipain-3: 0.25-39.8 microM). As the compounds also display in vitro activity against the P. falciparum parasite in the submicromolar and low micromolar range, these compound classes are leads for new antiplasmodial falcipain inhibitors. 相似文献
We investigated the toxicity of benzo[a]pyrene (B[a]P), 1-nitropyrene (1-NP) and 3-nitrobenzanthrone (3-NBA) in A549 cells. Cells were treated for 4 h and 24 h with: B[a]P (0.1 and 1 μM), 1-NP (1 and 10 μM) and 3-NBA (0.5 and 5 μM). Bulky DNA adducts, lipid peroxidation, DNA and protein oxidation and mRNA expression of CYP1A1, CYP1B1, NQO1, POR, AKR1C2 and COX2 were analyzed. Bulky DNA adducts were induced after both treatment periods; the effect of 1-NP was weak. 3-NBA induced high levels of bulky DNA adducts even after 4-h treatment, suggesting rapid metabolic activation. Oxidative DNA damage was not affected. 1-NP caused protein oxidation and weak induction of lipid peroxidation after 4-h incubation. 3-NBA induced lipid peroxidation after 24-h treatment. Unlike B[a]P, induction of the aryl hydrocarbon receptor, measured as mRNA expression levels of CYP1A1 and CYP1B1, was low after treatment with polycyclic aromatic hydrocarbon (PAH) nitro-derivatives. All test compounds induced mRNA expression of NQO1, POR, and AKR1C2 after 24-h treatment. AKR1C2 expression indicates involvement of processes associated with reactive oxygen species generation. This was supported further by COX2 expression induced by 24-h treatment with 1-NP. In summary, 3-NBA was the most potent genotoxicant, whereas 1-NP exhibited the strongest oxidative properties. 相似文献