The Effect of Long-Lasting Swimming on Rats Skeletal Muscles Energy Metabolism after Nine Days of Dexamethasone Treatment

This study investigates the effect of Dexamethasone (Dex) treatment on blood and skeletal muscle metabolites level and skeletal muscle activity of enzymes related to energy metabolism after long-duration swimming. To evaluate whether Dex treatment, swimming, and combining these factors act on analyzed data, rats were randomly divided into four groups: saline treatment non-exercise and exercise and Dex treatment non-exercised and exercised. Animals in both exercised groups underwent long-lasting swimming. The concentration of lipids metabolites, glucose, and lactate were measured in skeletal muscles and blood according to standard colorimetric and fluorimetric methods. Also, activities of enzymes related to aerobic and anaerobic metabolism were measured in skeletal muscles. The results indicated that Dex treatment induced body mass loss and increased lipid metabolites in the rats’ blood but did not alter these changes in skeletal muscles. Interestingly, prolonged swimming applied after 9 days of Dex treatment significantly intensified changes induced by Dex; however, there was no difference in skeletal muscle enzymatic activities. This study shows for the first time the cumulative effect of exercise and Dex on selected elements of lipid metabolism, which seems to be essential for the patient’s health due to the common use of glucocorticoids like Dex.     

Effects of Desolvating Agent Types,Ratios, and Temperature on Size and Nanostructure of Nanoparticles from α‐Lactalbumin and Ovalbumin

In this study, we compare the preparation of ovalbumin (OVA) and α‐lactalbumin (α‐LA) nanoparticles using different desolvating agents (ethanol, acetone, and methanol) and water: desolvating agent volume ratios (1:3, 1:4, 1:5, 1:10, and 1:20). Also the effects of protein solution temperature (25, 50, and 80 ℃) on the size of nanoparticles and the stability of crosslinked nanoparticles for 30 d were studied. OVA and α‐LA were shown to be good candidates for nanoparticulation and nanoparticles in the range of 60 to 230 nm were obtained. The comparison between the 2 proteins offers guidance to optimize OVA and α‐LA nanoparticle fabrication and to efficiently obtain nanoparticles with desired characteristics. The particle sizes of OVA nanoparticles were found to be in the range of 60 to 160 nm, and the particle sizes of α‐LA were between 150 and 230 nm. The sizes varied with different desolvating agents: for OVA, ethanol, and methanol both produced nanoparticles smaller than 100 nm; for α‐LA, methanol produced the smallest nanoparticles. Water: desolvating agent ratios, in the studied range, did not show a significant effect on the particle sizes for both OVA and α‐LA nanoparticles. The size and morphology of the nanoparticles were found to change when the protein solutions were heated up to 50 and 80 ℃ and cooled down before nanoparticulation and most nanoparticles had a smaller diameter.     

Concerted utility review of VVER-440 safety research needs (VERSAFE)

There are twelve operating VVER-440/213 reactors in the Czech Republic, Hungary and Slovakia. The plant owners have carried out extensive safety enhancement programmes, which have included measures to improve prevention, mitigation and control of design basis accidents. Recently, there have been a number of projects to study the Severe Accident Management aspects of these plants. The plant owners have also initiated Plant Life Management programmes. The objective of the VERSAFE Concerted Action is to create a network of the VVER-440/213 plant owners and operators, which aims at definition of the further research needs of severe accidents and plant ageing from the utilities’ viewpoint. The starting point is to formulate a general approach to severe accident management and plant life management and then proceed to define the needs for the additional information expected from the safety research. The role of national research institutes and organisations of the partner countries is of crucial importance in performing such research and, thus, creating and maintaining the expertise on the national level. The successful completion of the project will assist in establishing well-defined research projects that are oriented to the needs of the end-users and provide information that can be used to facilitate and support the negotiations of the EU applicant countries operating VVER-440 reactors.     

Emissions Production from Small Heat Sources Depending on Various Aspects

Mobile Networks and Applications - Solid fuels combustion is rather complicated because there is always environment pollution by emissions, mainly by particulate matter. The efforts of heat sources...     

Historical analysis of pharmacoeconomic terms

Scientometrics - Pharmacoeconomy is a young interdisciplinary science at the intersection of pharmacy, medicine and economics, focusing on the social aspects and implications of different types of...     

Study of a new energy efficient process for French fries production

A new, energy efficient production process for French fries was developed and evaluated. Superheated steam (SHS) was used for evaporation of water instead of pre-drying with air and par-frying with oil. The product was frozen by vacuum cooling. Unfortunately, with this process it was not possible to reach the quality of conventional French fries. Sensory analysis indicated that the main quality defect was a tough crust with a fatty appearance. Confocal Scanning Laser Microscopy showed that this was caused by skin formation on the surface during both SHS drying and vacuum cooling. A frying step was necessary to obtain a porous crust. A satisfactory product quality was feasible after drying with SHS instead of air. Due to the concessions made for the product quality, the final energy reduction was limited. Nevertheless, this study has gained more insight into how processing affects potato tissue on micro-scale and it has shown that a porous structure is essential for good quality French fries.     

The location of a resistive shunt harmonic impedance along a distribution feeder and its influence on harmonic propagation

Although complete compensation is only possible using true active filters, resistive shunt harmonic impedances (SHI) have been shown to provide a considerable reduction of the harmonic propagation. In this paper, the harmonic mitigation potential of a resistive SHI is discussed concerning its influence on the voltage distortion profile along a typical distribution feeder, with the location of the SHI along the feeder as a parameter. Although the distortion values are dependent on the SHI location, it is shown that the end of the feeder is generally a good location to install the SHI, especially when the power system parameters can vary or are unknown. Calculations are performed on a typical radial distribution feeder. Both the power factor correction capacitors and the non-linear loads are concentrated in single nodes. The linear loads are disconnected to obtain the worst case for the voltage distortion. Also some measurements on a scale model of a typical distribution feeder are done and the experimental results confirm the results obtained from simulations.     

e-R&D – Effectively Managing Process Diversity

Managing process diversity becomes increasingly relevant in software development. Software organizations typically do not work on the greenfield and thus need to integrate external workflows with R&;D internal workflow management and heterogeneous development and maintenance processes. To stay competitive with its software development, Alcatel has put in place an orchestrated improvement program of its processes and the underlying engineering tools environment. Why do we call this “e-R&;D”? For two reasons. These improvement activities necessarily fit into the wider context of Alcatel's business process improvement and corporate e-business initiatives. The “e-R&;D” also means enabling of interactive R&;D processes and increasing collaborative work across the globe. At Alcatel we realized, during a substantial reengineering of our development and industrialization processes, that the approach to acquire an off-the-shelf process and tailor it to our needs was not applicable. Different processes need to be seamlessly integrated to avoid inconsistencies and inefficiency caused by replicated work. Specific focus is given within this article on how we manage process diversity in a product line where various components are embedded in individual architectures, asking for different but defined development and maintenance processes depending on pre-selected criteria.     

DAMAGE OF FABA BEAN SEEDS DURING DRYING

Experiments have been carried out to determine a relation between mechanical properties, microstructure and drying conditions of faba bean seeds and their damages during single-stage drying. Results showed that physical damages of beans strongly depend on drying parameters, i.e.drying time and temperature, air flow rate and variety of seeds. It was revealed that some seed parts: the hilum and embryonal axis play a special role in the cracking mechanism of seeds.     

A broader view on the limitations of information processing and communication by nature

Several new and broader views on computation in Nature and by Nature, and on its limitations and barriers are presented and analysed briefly. Quantum information precessing, global network information processing and cosmology-based information processing theories are seen as three extreme, but well-founded approaches to computation by Nature. It is also emphasized that a search for barriers and limitations in information processing as well as attempts to overcome their barriers or to shift limitations, can have deep impacts on science, especially if they are accompanied by a search for limitations and barriers also in communication and security. It is demonstrated that a search for barriers in communications brings a lot of interesting and deep outcomes. Computational and communication complexity is shown to play an important role in evaluating various approaches to get through barriers that current physical theories impose. It is also argued that a search for barriers and limitations concerning feasibility in information processing and physical worlds are of equal or maybe even of larger importance than those to overcome the Church-Turing barrier and some communication barriers. It is also emphasized that relations between information processing in the real and virtual worlds, or between physical and information worlds, are likely very deep and more complex than realized. All that has even broader sense than usually realized because we are witnessing a radical shift in the main characterization of the current science in general. A shift from so called Galilean science dominated by mathematics, to the Informatics (based) science - an informatics methodology based science and technology. This is an extended version of a paper (Thies et al. 2006) that appeared in the 12th International Meeting on DNA Computing, June, 2006.