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61.
Multimedia Tools and Applications - In this paper, a hashing based watermarking technique for the protection and authentication of document image is proposed. Message Digest 5 (MD5) hashing is...  相似文献   
62.
Ferroptosis is gaining followers as mechanism of selective killing cancer cells in a non-apoptotic manner, and novel nanosystems capable of inducing this iron-dependent death are being increasingly developed. Among them, polydopamine nanoparticles (PDA NPs) are arousing interest, since they have great capability of chelating iron. In this work, PDA NPs were loaded with Fe3+ at different pH values to assess the importance that the pH may have in determining their therapeutic activity and selectivity. In addition, doxorubicin was also loaded to the nanoparticles to achieve a synergist effect. The in vitro assays that were performed with the BT474 and HS5 cell lines showed that, when Fe3+ was adsorbed in PDA NPs at pH values close to which Fe(OH)3 begins to be formed, these nanoparticles had greater antitumor activity and selectivity despite having chelated a smaller amount of Fe3+. Otherwise, it was demonstrated that Fe3+ could be released in the late endo/lysosomes thanks to their acidic pH and their Ca2+ content, and that when Fe3+ was co-transported with doxorubicin, the therapeutic activity of PDA NPs was enhanced. Thus, reported PDA NPs loaded with both Fe3+ and doxorubicin may constitute a good approach to target breast tumors.  相似文献   
63.
Marrone  Mauricio  Lemke  Sascha  Kolbe  Lutz M. 《Scientometrics》2022,127(7):3857-3878
Scientometrics - Computer-assisted methods and tools can help researchers automate the coding process of literature reviews and accelerate the literature review process. However, existing...  相似文献   
64.

Probabilistic topic modeling algorithms like Latent Dirichlet Allocation (LDA) have become powerful tools for the analysis of large collections of documents (such as papers, projects, or funding applications) in science, technology an innovation (STI) policy design and monitoring. However, selecting an appropriate and stable topic model for a specific application (by adjusting the hyperparameters of the algorithm) is not a trivial problem. Common validation metrics like coherence or perplexity, which are focused on the quality of topics, are not a good fit in applications where the quality of the document similarity relations inferred from the topic model is especially relevant. Relying on graph analysis techniques, the aim of our work is to state a new methodology for the selection of hyperparameters which is specifically oriented to optimize the similarity metrics emanating from the topic model. In order to do this, we propose two graph metrics: the first measures the variability of the similarity graphs that result from different runs of the algorithm for a fixed value of the hyperparameters, while the second metric measures the alignment between the graph derived from the LDA model and another obtained using metadata available for the corresponding corpus. Through experiments on various corpora related to STI, it is shown that the proposed metrics provide relevant indicators to select the number of topics and build persistent topic models that are consistent with the metadata. Their use, which can be extended to other topic models beyond LDA, could facilitate the systematic adoption of this kind of techniques in STI policy analysis and design.

  相似文献   
65.
Journal of Materials Science: Materials in Electronics - Nano Mn0.95M0.05S (M ≡ Cu, Mg) samples were produced using molten salt solid state reaction method. Rietveld analysis of X-ray...  相似文献   
66.
Chemical and Petroleum Engineering - The hydrodynamics of oxidation towers used for bitumen production were studied using a model tower having transparent walls. Experiments were carried out in two...  相似文献   
67.
Journal of Engineering Physics and Thermophysics - Results of investigation into the influence of a corrosion process on thermotechnical characteristics of heat pipes of low-temperature range are...  相似文献   
68.
Deshmukh  P.  Sar  S. K.  Smječanin  N.  Nuhanović  M.  Lalwani  R. 《Radiochemistry》2022,64(4):532-542
Radiochemistry - Magnetically modified waste bark of the Aegle marmelos tree was prepared by using green synthesis method and was used in a batch system for U(VI) removal from aqueous solution. The...  相似文献   
69.
Kamar  M. S.  Shalan  A. S.  Youssef  W. M.  Hussein  A. E. M.  Khawassek  Y. M.  Taha  M. H. 《Radiochemistry》2022,64(2):244-256
Radiochemistry - Ferrugination, sericitization, desulfitization, chloritization, and kaolinitization of hydrothermal origin are the main wall rock alterations occurring within the NNW shear zones...  相似文献   
70.
This paper reports an investigation on the structure-properties correlation of trivalent metal oxide (Al2O3)-doped V2O5 ceramics synthesized by the melt-quench technique. XRD patterns confirmed a single orthorhombic V2O5 phase formation with increasing strain on the doping of Al2O3 in place of V2O5 in the samples estimated by Williamson-Hall analysis. FTIR and Raman investigations revealed a structural change as [VO5] polyhedra converts into [VO4] polyhedra on the doping of Al2O3 into V2O5. The optical band gap was found in a wide semiconductor range as confirmed by UV–visible spectroscopy analysis. The thermal and conductivity behavior of the prepared samples were studied using thermal gravimetric analysis (TGA) and impedance analyzer, respectively. All the prepared ceramics exhibit good DC conductivity (0.22–0.36 Sm-1) at 400 ?C. These materials can be considered for intermediate temperature solid oxide fuel cell (IT-SOFC)/battery applications due to their good conductivity and good thermal stability.  相似文献   
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