Emulation of complex open quantum systems using superconducting qubits

With quantum computers being out of reach for now, quantum simulators are alternative devices for efficient and accurate simulation of problems that are challenging to tackle using conventional computers. Quantum simulators are classified into analog and digital, with the possibility of constructing “hybrid” simulators by combining both techniques. Here we focus on analog quantum simulators of open quantum systems and address the limit that they can beat classical computers. In particular, as an example, we discuss simulation of the chlorosome light-harvesting antenna from green sulfur bacteria with over 250 phonon modes coupled to each electronic state. Furthermore, we propose physical setups that can be used to reproduce the quantum dynamics of a standard and multiple-mode Holstein model. The proposed scheme is based on currently available technology of superconducting circuits consist of flux qubits and quantum oscillators.     

Micromixing with spark-generated cavitation bubbles

The intrinsic laminarity of microfluidic devices impedes the mixing of multiple fluids over short temporal or spatial scales. Despite the existence of several mixers capable of stirring and stretching the flows to promote mixing, most approaches sacrifice temporal or spatial control, portability, or flexibility in terms of operating flow rates. Here, we report a novel method for rapid micromixing based on the generation of cavitation bubbles. By using a portable battery-powered electric circuit, we induce a localized electric spark between two tip electrodes perpendicular to the flow channel that results in several cavitation events. As a result, a vigorous stirring mechanism is induced. We investigate the spatiotemporal dynamics of the spark-generated cavitation bubbles and quantify the created flow disturbance. We demonstrate rapid (in the millisecond timescale) and efficient micromixing (up to 98%) within a length scale of only 200 µm and over a flow rate ranging from 5 to 40 µL/min.     

Microfluidic device with dual-channel fluorescence acquisition for quantification/identification of cancer cells

This paper presents an optofluidic device for cell discrimination with two independent interrogation regions. Pumping light is coupled to the device, and cell fluorescence is extracted from the two interrogation zones by using optical fibers embedded in the optofluidic chip. To test the reliability of this device, AU-565 cells—expressing EpCAM and HER2 receptors—and RAMOS cells were mixed in a controlled manner, confined inside a hydrodynamic focused flow in the microfluidic chip and detected individually so that they could be discriminated as positive (signal reception from fluorescently labeled antibodies from the AU-565 cells) or negative events (RAMOS cells). A correlation analysis of the two signals reduces the influence of noise on the overall data.     

Semantic integration of enterprise information systems using meta-metadata ontology

This paper proposes a non-domain-specific metadata ontology as a core component in a semantic model-based document management system (DMS), a potential contender towards the enterprise information systems of the next generation. What we developed is the core semantic component of an ontology-driven DMS, providing a robust semantic base for describing documents’ metadata. We also enabled semantic services such as automated semantic translation of metadata from one domain to another. The core semantic base consists of three semantic layers, each one serving a different view of documents’ metadata. The core semantic component’s base layer represents a non-domain-specific metadata ontology founded on ebRIM specification. The main purpose of this ontology is to serve as a meta-metadata ontology for other domain-specific metadata ontologies. The base semantic layer provides a generic metadata view. For the sake of enabling domain-specific views of documents’ metadata, we implemented two domain-specific metadata ontologies, semantically layered on top of ebRIM, serving domain-specific views of the metadata. In order to enable semantic translation of metadata from one domain to another, we established model-to-model mappings between these semantic layers by introducing SWRL rules. Having the semantic translation of metadata automated not only allows for effortless switching between different metadata views, but also opens the door for automating the process of documents long-term archiving. For the case study, we chose judicial domain as a promising ground for improving the efficiency of the judiciary by introducing the semantics in this field.     

The effect of price promotions on consumer shopping behavior across online and offline channels: differences between frequent and non-frequent shoppers

Information Systems and e-Business Management - This study evaluates the differential effect of price promotions on brand choice across the offline and online channels of a grocery retailer. We use...     

A case study about the improvement of business process models driven by indicators

Organizations are increasingly concerned about business process model improvement in their efforts to guarantee improved operational efficiency. Quality assurance of business process models should be addressed in the most objective manner, e.g., through the application of measures, but the assessment of measurement results is not a straightforward task and it requires the identification of relevant indicators and threshold values, which are able to distinguish different levels of process model quality. Furthermore, indicators must support the improvements of the models by using suitable guidelines. In this paper, we present a case study to evaluate the BPMIMA framework for BP model improvement. This framework is composed of empirically validated measures related to quality characteristics of the models, a set of indicators with validated thresholds associated with modeling guidelines and a prototype supporting tool. The obtained data suggest that the redesign by applying guidelines driven by the indicator results was successful, as the understandability and modifiability of the models were improved. In addition, the changes in the models according to guidelines were perceived as acceptable by the practitioners who participated in the case study.     

FLAME: a formal framework for the automated analysis of software product lines validated by automated specification testing

In a literature review on the last 20 years of automated analysis of feature models, the formalization of analysis operations was identified as the most relevant challenge in the field. This formalization could provide very valuable assets for tool developers such as a precise definition of the analysis operations and, what is more, a reference implementation, i.e., a trustworthy, not necessarily efficient implementation to compare different tools outputs. In this article, we present the FLAME framework as the result of facing this challenge. FLAME is a formal framework that can be used to formally specify not only feature models, but other variability modeling languages (VML s) as well. This reusability is achieved by its two-layered architecture. The abstract foundation layer is the bottom layer in which all VML-independent analysis operations and concepts are specified. On top of the foundation layer, a family of characteristic model layers—one for each VML to be formally specified—can be developed by redefining some abstract types and relations. The verification and validation of FLAME has followed a process in which formal verification has been performed traditionally by manual theorem proving, but validation has been performed by integrating our experience on metamorphic testing of variability analysis tools, something that has shown to be much more effective than manually designed test cases. To follow this automated, test-based validation approach, the specification of FLAME, written in Z, was translated into Prolog and 20,000 random tests were automatically generated and executed. Tests results helped to discover some inconsistencies not only in the formal specification, but also in the previous informal definitions of the analysis operations and in current analysis tools. After this process, the Prolog implementation of FLAME is being used as a reference implementation for some tool developers, some analysis operations have been formally specified for the first time with more generic semantics, and more VML s are being formally specified using FLAME.     

Consensus and disturbance attenuation in multi‐agent chains with nonlinear control and time delays

In this paper, we investigate consensus and disturbance attenuation in a chain of mobile agents, which include non‐autonomous agents, semi‐autonomous agents and autonomous agents. In particular, the nonlinear dynamics of non‐autonomous agents is given and cannot be designed, while the dynamics of semi‐autonomous and autonomous agents can be partially and fully designed, respectively. To improve the robustness of multi‐agent chains against disturbances, we propose a nonlinear control framework for semi‐autonomous and autonomous agents such that they mimic the behavior of non‐autonomous agents for compatibility while also exploiting long‐range connections with distant agents. This framework ensures the existence of a unique consensus equilibrium, which is independent of the network size, connectivity topologies, control gains and information delays. Robustness of multi‐agent chains against disturbances is investigated by evaluating the frequency response at the nonlinear level. For infinitely long multi‐agent chains with recurrent patterns, we also derive a condition that ensures the disturbance attenuation but only requires the analysis of the linearized model. A case study is conducted for a connected vehicle system where numerical simulations are used to validate the analytical results. Copyright © 2016 John Wiley & Sons, Ltd.     

Theory blending: extended algorithmic aspects and examples

In Cognitive Science, conceptual blending has been proposed as an important cognitive mechanism that facilitates the creation of new concepts and ideas by constrained combination of available knowledge. It thereby provides a possible theoretical foundation for modeling high-level cognitive faculties such as the ability to understand, learn, and create new concepts and theories. Quite often the development of new mathematical theories and results is based on the combination of previously independent concepts, potentially even originating from distinct subareas of mathematics. Conceptual blending promises to offer a framework for modeling and re-creating this form of mathematical concept invention with computational means. This paper describes a logic-based framework which allows a formal treatment of theory blending (a subform of the general notion of conceptual blending with high relevance for applications in mathematics), discusses an interactive algorithm for blending within the framework, and provides several illustrating worked examples from mathematics.     

Reliability and time‐to‐failure bounds for discrete‐time constrained Markov jump linear systems

This paper presents a methodology to obtain a guaranteed‐reliability controller for constrained linear systems, which switch between different modes according to a Markov chain (Markov jump linear systems). Inside the classical maximal robust controllable set, there is 100% guarantee of never violating constraints at future time. However, outside such set, some sequences might make hitting constraints unavoidable for some disturbance realisations. A guaranteed‐reliability controller based on a greedy heuristic approach was proposed in an earlier work for disturbance‐free, robustly stabilisable Markov jump linear systems. Here, extensions are presented by, first, considering bounded disturbances and, second, presenting an iterative algorithm based on dynamic programming. In non‐stabilisable systems, reliability is zero; therefore, prior results cannot be applied; in this case, optimisation of a mean‐time‐to‐failure bound is proposed, via minor algorithm modifications. Optimality can be proved in the disturbance‐free, finitely generated case. Copyright © 2016 John Wiley & Sons, Ltd.