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排序方式: 共有68条查询结果,搜索用时 46 毫秒
21.
Ajna Tóth Kateryna V. Voitko Olga Bakalinska Gennadiy P. Prykhod’ko Imre Bertóti Amelia Martínez-Alonso Juan M.D. Tascón Vladimir M. Gun’ko Krisztina László 《Carbon》2012,50(2):577-585
The poor compatibility of carbon materials with different dispersion media can be overcome by surface functionalization. In this work, multiwall carbon nanotubes (MWCNTs) were doped by oxygen and nitrogen at low concentrations. Morphological and structural changes caused by chemical treatment were monitored using nitrogen, propane and water vapor adsorption measurements. Pore size distribution (PSD) functions derived from various models are compared. The contribution of slit-shaped pores to the total surface area available for adsorbed molecules is smaller than that of cylindrical pores. Functionalities with heteroatoms (both O and N) enhance water adsorption onto MWCNTs. However, no statistical difference is observed between the water adsorption properties of O- or N-containing MWCNTs. 相似文献
22.
Carolyn A. Watters Kateryna V. Keefer Patricia H. Kloosterman Laura J. Summerfeldt James D.A. Parker 《Computers in human behavior》2013
Young’s (1998a) Internet Addiction Test (IAT) is one of the most commonly used measures of problematic Internet use. Although the instrument is being increasingly applied in research with adolescents, its measurement structure has not been systematically evaluated with pre-adult respondents. Because the results of previous factor-analytic studies with adults have been highly inconsistent, the present study applied both the traditional (simple-structure) and novel (bifactor) modeling approaches to derive the most optimal measurement structure of the IAT for adolescents. The results of exploratory and confirmatory analyses in a large Canadian sample of high-school students (N = 1948) converged on a bifactor model with a dominant global IA factor and two distinct sub-dimensions, each associated with a unique gender and problem behaviour profile. The discussion focuses on the implications of this bifactor structure for scale scoring and substantive theory on the nature and sources of individual differences in Internet addiction. 相似文献
23.
Csilla Lea Fazekas Adrienn Szab Bibina Trk Krisztina Bnrvi Pedro Correia Tiago Chaves Stphanie Daumas Dra Zelena 《International journal of molecular sciences》2022,23(2)
Glutamate is the most abundant excitatory amino acid in the central nervous system. Neurons using glutamate as a neurotransmitter can be characterised by vesicular glutamate transporters (VGLUTs). Among the three subtypes, VGLUT3 is unique, co-localising with other “classical” neurotransmitters, such as the inhibitory GABA. Glutamate, manipulated by VGLUT3, can modulate the packaging as well as the release of other neurotransmitters and serve as a retrograde signal through its release from the somata and dendrites. Its contribution to sensory processes (including seeing, hearing, and mechanosensation) is well characterised. However, its involvement in learning and memory can only be assumed based on its prominent hippocampal presence. Although VGLUT3-expressing neurons are detectable in the hippocampus, most of the hippocampal VGLUT3 positivity can be found on nerve terminals, presumably coming from the median raphe. This hippocampal glutamatergic network plays a pivotal role in several important processes (e.g., learning and memory, emotions, epilepsy, cardiovascular regulation). Indirect information from anatomical studies and KO mice strains suggests the contribution of local VGLUT3-positive hippocampal neurons as well as afferentations in these events. However, further studies making use of more specific tools (e.g., Cre-mice, opto- and chemogenetics) are needed to confirm these assumptions. 相似文献
24.
Bibina Trk Pter Csikota Anna Fodor Dina Balzsfi Szilamr Ferenczi Kornl Demeter Zsuzsanna E. Tth Katalin Knczl Judith Camats Perna Imre Farkas Krisztina J. Kovcs Jzsef Haller Mario Engelmann Dra Zelena 《International journal of molecular sciences》2022,23(3)
The relevance of vasopressin (AVP) of magnocellular origin to the regulation of the endocrine stress axis and related behaviour is still under discussion. We aimed to obtain deeper insight into this process. To rescue magnocellular AVP synthesis, a vasopressin-containing adeno-associated virus vector (AVP-AAV) was injected into the supraoptic nucleus (SON) of AVP-deficient Brattleboro rats (di/di). We compared +/+, di/di, and AVP-AAV treated di/di male rats. The AVP-AAV treatment rescued the AVP synthesis in the SON both morphologically and functionally. It also rescued the peak of adrenocorticotropin release triggered by immune and metabolic challenges without affecting corticosterone levels. The elevated corticotropin-releasing hormone receptor 1 mRNA levels in the anterior pituitary of di/di-rats were diminished by the AVP-AAV-treatment. The altered c-Fos synthesis in di/di-rats in response to a metabolic stressor was normalised by AVP-AAV in both the SON and medial amygdala (MeA), but not in the central and basolateral amygdala or lateral hypothalamus. In vitro electrophysiological recordings showed an AVP-induced inhibition of MeA neurons that was prevented by picrotoxin administration, supporting the possible regulatory role of AVP originating in the SON. A memory deficit in the novel object recognition test seen in di/di animals remained unaffected by AVP-AAV treatment. Interestingly, although di/di rats show intact social investigation and aggression, the SON AVP-AAV treatment resulted in an alteration of these social behaviours. AVP released from the magnocellular SON neurons may stimulate adrenocorticotropin secretion in response to defined stressors and might participate in the fine-tuning of social behaviour with a possible contribution from the MeA. 相似文献
25.
Yong Xu Tatsuya Hiramatsu Kateryna Tarasenko Toyoaki Nishida Yoshiyasu Ogasawara Takashi Tajima Makoto Hatakeyama Masashi Okamoto Yukiko I. Nakano 《AI & Society》2007,22(2):185-196
A key issue in social intelligence design is the realization of artifacts that can fluently communicate with people. Thus,
we proposed a two-layered approach to enhance a robot’s capacity of involvement and engagement. The upper layer flexibly controls
social interaction by dynamic Bayesian networks (DBN) representing social interaction patterns. The lower layer improves the
robustness of the system by detecting rhythmic and repetitive gestures. We designed a listener robot that can follow and record
humans’ explanation on how to assemble and/or disassemble a bicycle. The implementation of this system is described by assembling
the key algorithms presented in this paper. 相似文献
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29.
Dmytro Nozdrenko Tetiana Matvienko Oksana Vygovska Kateryna Bogutska Olexandr Motuziuk Natalia Nurishchenko Yuriy Prylutskyy Peter Scharff Uwe Ritter 《International journal of molecular sciences》2021,22(13)
The biomechanical parameters of muscle soleus contraction in rats and their blood biochemical indicators after the intramuscular administration of water-soluble C60 fullerene at doses of 0.5, 1, and 2 mg/kg 1 h before the onset of muscle ischemia were investigated. In particular, changes in the contraction force of the ischemic muscle soleus, the integrated power of the muscle, the time to achieve the maximum force response, the dynamics of fatigue processes, and the parameters of the transition from dentate to smooth tetanus, levels of creatinine, creatine kinase, lactate and lactate dehydrogenase, and parameters of prooxidant–antioxidant balance (thiobarbituric acid reactive substances, hydrogen peroxide, and reduced glutathione and catalase) were analyzed. The positive therapeutic changes in the studied biomechanical and biochemical markers were revealed, which indicate the possibility of using water-soluble C60 fullerenes as effective prophylactic nanoagents to reduce the severity of pathological conditions of the muscular system caused by ischemic damage to skeletal muscles. 相似文献
30.
设计了一种通过检测生物活性点与皮肤完整区域之间温度差来监测药物疗效并优化心理疾病治疗的系统。该系统通过实时监控服药计量,以及时调整药量,从而提高治疗的有效性。系统采用两电极 Foll方法结合中该地形解剖参考点找到生物活性点,通过 DS18B20测量温度,利用 ATmega 32单片机对温度进行处理并实时显示温度差,进而通过温度差反应药效。本文数据证实了温差指标 BAP C7、Gi4与评估心理疾病严重程度的神经尺度之间的相关性。实验结果表明,温度差指标能够作为衡量药效的标准,通过监测温度差可以有效实现心理疾病药效的监测。 相似文献