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101.
Kelly Carlson-Reddig 《Journal of Architectural Education》2013,67(2):96-104
This article addresses the struggle that architecture students undergo in their efforts to develop critical thinking regarding architecture's materiality. It describes work that evolved through a seminar entitled “Intention and Materiality,” which explored theoretical frameworks for a variety of historical, technological, contextual, and subjective issues affecting decisions about materials. This article briefly outlines the nature and structure of the seminar, and then provides a broad-based discussion and elaboration of students' ideas and concerns about the role of materials in architecture. Collectively, their ideas reveal inspiring insight and thoughtfulness about questions that are frequently of great concern to architects and educators today. 相似文献
102.
103.
Srivastava Sanjay; Tamir Maya; McGonigal Kelly M.; John Oliver P.; Gross James J. 《Canadian Metallurgical Quarterly》2009,96(4):883
There is growing interest in understanding how emotion regulation affects adaptation. The present study examined expressive suppression (which involves inhibiting the overt expression of emotion) and how it affects a critical domain of adaptation, social functioning. This investigation focused on the transition to college, a time that presents a variety of emotional and social challenges. Analyses focused on 2 components of suppression: a stable component, representing individual differences expressed both before and after the transition, and a dynamic component, representing variance specific to the new college context. Both components of suppression predicted lower social support, less closeness to others, and lower social satisfaction. These findings were robustly corroborated across weekly experience reports, self-reports, and peer reports and are consistent with a theoretical framework that defines emotion regulation as a dynamic process shaped by both stable person factors and environmental demands. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
104.
A two-dimensional, particle-based biofilm model coupled with mass transport and computational fluid dynamics was developed to simulate autotrophic denitrification in a spiral-wound membrane biofilm reactor (MBfR), where hydrogen is supplied via hollow-fiber membrane fabric. The spiral-wound configuration consists of alternating layers of plastic spacer net and membrane fabric that create rows of flow channels, with the top and bottom walls comprised of membranes. The transversal filaments of the spacer partially obstruct the channel flow, producing complex mixing and shear patterns that require multidimensional representation. This study investigated the effect of hydrogen and nitrate concentrations, as well as spacer configuration, on biofilm development and denitrification fluxes. The model results indicate that the cavity spacer filaments, which rest on the bottom membranes, cause uneven biofilm growth. Most biofilm resided on the bottom membranes, only in the wake of the filaments where low shear zones formed. In this way, filament configuration may help achieve a desired biofilm thickness. For the conditions tested in this study, the highest nitrate fluxes were attained by minimizing the filament diameter and maximizing the filament spacing. This lowered the shear stress at the top membranes, allowing for more biofilm growth. For the scenarios studied, biomass limitation at the top membranes hindered performance more significantly than diffusion limitation in the thick biofilms at the bottom membranes. The results also highlighted the importance of two-dimensional modeling to capture uneven biofilm growth on a substratum with geometrical complexity. 相似文献
105.
John Kelly 《Construction Management & Economics》2013,31(4):435-442
Value management is a project‐focused process that makes explicit and appraises the functional benefits of a product, process or service consistent with a value system determined by the client. The value system of the client necessarily requires a method for value setting using harder performance variables than the commonly described facets of time, cost and quality. Current value theory is critically appraised in the context of current value management practice. The research proposition is that the constituent parts of time, cost and quality can be made overt enabling a client to express satisfaction in terms of a finite number of variables enabling the explicit statement of client value within a value management workshop. An action research study into the discovery of the component parts of the client's value system at the early stages of construction projects concludes that the variables are the nine non‐correlated, high order, discretionary performance variables of capital expenditure, operational expenditure, time, esteem, environment, exchange, politics/community, flexibility and comfort. 相似文献
106.
107.
Wax Ester Rich Oil From The Marine Crustacean,Calanus finmarchicus,is a Bioavailable Source of EPA and DHA for Human Consumption 下载免费PDF全文
Chad M. Cook Terje S. Larsen Linda D. Derrig Kathleen M. Kelly Kurt S. Tande 《Lipids》2016,51(10):1137-1144
Oil from the marine copepod, Calanus finmarchicus, which contains >86 % of fatty acids present as wax esters, is a novel source of n‐3 fatty acids for human consumption. In a randomized, two‐period crossover study, 18 healthy adults consumed 8 capsules providing 4 g of Calanus® Oil supplying a total of 260 mg EPA and 156 mg DHA primarily as wax esters, or 1 capsule of Lovaza® providing 465 mg EPA and 375 mg DHA as ethyl esters, each with an EPA‐ and DHA‐free breakfast. Plasma EPA and DHA were measured over a 72 h period (t = 1, 2, 4, 6, 8, 10, 12, 24, 48, and 72 h). The positive incremental area under the curve over the 72 h test period (iAUC0‐72 h) for both EPA and DHA was significantly different from zero (p < 0.0001) in both test conditions, with similar findings for the iAUC0–24 h and iAUC0–48 h, indicating the fatty acids were absorbed. There was no difference in the plasma iAUC0–72 h for EPA + DHA, or DHA individually, in response to Calanus Oil vs the ethyl ester condition; however, the iAUC0–48 h and iAUC0–72 h for plasma EPA in response to Calanus Oil were both significantly increased relative to the ethyl ester condition (iAUC0–48 h: 381 ± 31 vs 259 ± 39 μg*h/mL, p = 0.026; iAUC0‐72 h: 514 ± 47 vs 313 ± 49 μg*h/mL, p = 0.009). These data demonstrate a novel wax ester rich marine oil is a suitable alternative source of EPA and DHA for human consumption. 相似文献
108.
Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues 下载免费PDF全文
Dr. Mostafa E. Abugrain Dr. Wanli Lu Dr. Yuexin Li Dr. Jeffrey D. Serrill Corey J. Brumsted Andrew R. Osborn Prof. Dr. Adam Alani Prof. Dr. Jane E. Ishmael Prof. Dr. Jane X. Kelly Prof. Dr. Taifo Mahmud 《Chembiochem : a European journal of chemical biology》2016,17(17):1585-1588
Pactamycin is a bacteria‐derived aminocyclitol antibiotic with a wide‐range of biological activity. Its chemical structure and potent biological activities have made it an interesting lead compound for drug discovery and development. Despite its unusual chemical structure, many aspects of its formation in nature remain elusive. Using a combination of genetic inactivation and metabolic analysis, we investigated the tailoring processes of pactamycin biosynthesis in Streptomyces pactum. The results provide insights into the sequence of events during the tailoring steps of pactamycin biosynthesis and explain the unusual production of various pactamycin analogues by S. pactum mutants. We also identified two new pactamycin analogues that have better selectivity indexes than pactamycin against malarial parasites. 相似文献
109.
Kelly Gregg 《Planning Perspectives》2019,34(4):551-577
Pedestrianization was an established concept among modernist architects and planners long before the first post-war pedestrian malls were built in North American downtowns. Post-war pedestrian-oriented suburban shopping malls, such as Northland near Detroit, MI and Northgate in Seattle, WA, linked retail success to the pedestrian shopping experience. This propelled the existing but then-untested assumption that planning downtowns to mimic suburban shopping centres by pedestrianizing main streets would revitalize downtown retail districts. Despite the modern origins of the pedestrianization concept, the rhetorical cues of post-war architects and planners in North America mask its modern roots and employ nostalgic imagery of pre-industrial European urbanism, implying European origin of the concept. Although imagery of European charm became a means of packaging modernist ideas of pedestrianization, the design proposals rarely referenced or replicated actual European precedents. Furthermore, while much research implies a linear transfer of pedestrianization ideas from Europe to North America, professionals in Europe also looked to North American shopping malls and pedestrian streets for guidance in addressing their own challenges with accommodating automobiles in downtowns. 相似文献
110.
The effect on the physical properties and solubility of corn protein (zein) films was studied after reaction of zein with polyethylenemaleic anhydride (PEMA). Reactions were carried out in dimethylformamide (DMF) solution where the concentration of PEMA was varied between 0 and 6%. After reaction at room temperature, cast films were prepared, and the physical and solubility properties were determined. Incorporating more than 2% PEMA provided films with increased tensile strength and elongation. Incorporating 6% PEMA provided films with higher tensile strength (32–42 MPa) and improved solvent resistance (100–21% solubility) relative to control. If the films were heated in an oven, the film's solubility decreased further. Solution rheology experiments demonstrated that the zein and PEMA formed a cross‐linked gel with time in DMF. Dynamic mechanical analysis experiments have shown that the PEMA‐modified zein films undergo a dramatic loss in modulus on reaching 116°C, whereas the control experiences this loss at 98°C. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 40122. 相似文献