构建柏林都市区的未来--分散型集中

15年前柏林城市规划的定义与现在完全不同.至今,柏林的两个组成部分还有不同的规划理念:一方面,在西柏林.规划严格控制在划定的50平方公里两百万居民的边线范围内;另一方面,在前东德首都的东柏林.所有活动集中在有限的中心地区以展示其首都功能.而柏林周边地区没有包含在任何区域规划系统内.这样的结果导致东、西柏林以及柏林同周边乡镇有完全不同的生活方式.     

Fibre-polarimeter based on grating taps

The fabrication of novel tilted fibre Bragg gratings coupling light out of the fibre core into two different directions is demonstrated. These gratings in combination with a fibre based quarter waveplate are used to form a high-speed fibre polarimeter for real-time polarisation monitoring.     

Analysis of clinical trial data: The problem of outcome overlap.

The immediate goal of any clinical trial is to determine to which of a specified set of treatments future patients are to be assigned, particularly when analyzing data from clinical trials. When the outcome distributions of Experimental (E) and Control (C) treatments overlap, differences between treatment group means are not conclusive and may not be very informative, so a display of the overlapped frequency distributions and a summary measure of the probability of a random patient in E doing better than a random patient in C are needed. When outcome distributions overlap, the question of statistical model becomes crucial even when there are very significant differences between group means and very large effect sizes. Determining what patient variables interact with treatments is the route to optimal assignment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The content of asbestos bodies in the bronchoalveolar fluid as a parameter of an increased pulmonary asbestos load

Pulmonary asbestos burdens are usually determined by quantitative pulmonary dust analysis. The aim of this study was to investigate the value of bronchoalveolar lavage (BAL) for this purpose. First, the upper limit of normal for asbestos bodies (AB) in BAL fluid was established using a reference group of 371 patients with no evidence of increased exposure to asbestos. 99% of these patients had less than 0.5 AB/ml. In order to see whether BAL fluid AB concentration reflected pulmonary tissue content, BAL fluid and lung tissue from a further 64 patients with diverse histories of asbestos exposure were investigated. There was a positive association between AB concentration in BAL fluid and lung tissue only for the overall group of 64 patients (r = 0.86; P < 0.001). Twelve of 13 patients with more than 1 AB/ml and ten patients with more than 5 AB/ml had more than 1000 AB/cm3 lung tissue, a value that is usually exceeded in asbestosis. When the upper concentration limit was set at 0.5 AB/ml for BAL fluid and 50 AB/cm3 for lung tissue, only two out of 64 patients had a false positive value (specificity 95%), but eleven patients had false negative results (sensitivity 58%). These investigations establish that concentrations of > or = 0.5 AB/ml are a reliable indicator of increased asbestos exposure and concentrations > 1 AB/ml are associated with a higher probability of having more than 1000 AB/cm3 lung tissue. However, exclusion of increased asbestos exposure is not possible on the basis of negative BAL findings, since the sensitivity of the method is too low.