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991.
Shot-peening is widely used in the aerospace industry to enhance the resistance of structural components to fatigue damage and stress corrosion by putting the outside layer of a component under an initial, residual compressive stress. The ability to measure these near-surface residual stresses is useful from a quality control and certification perspective, and can help predict the fatigue life of shot-peened components. This paper presents experimental results to examine the feasibility of measuring near-surface residual stresses using nonlinear Rayleigh surface waves. Experiments are conducted on aluminum alloy (AA 7075) samples shot-peened at different peening intensities and thus with different levels of residual stresses. The surface roughness of these samples is also measured. The nonlinear ultrasonic results show a large increase in the acoustic nonlinearity parameter, indicating the potential of nonlinear ultrasonics for the in situ measurement of near-surface residual stresses. The effects of surface roughness and the driving frequency on the measured acoustic nonlinearity parameter are briefly discussed. Finally, a preliminary model is used to interpret some experimental results. Future work to evaluate the separate contributions of cold work, residual stress and surface roughness to the total measured nonlinearity is also discussed.  相似文献   
992.
The oxidation state of chromium in glasses melted in an air atmosphere with and without refining agents was investigated by Cr K-edge X-ray absorption near-edge structure (XANES) and optical absorption spectroscopy. A good agreement in the relative proportion of Cr(III) and Cr(VI) is obtained between both methods. We show that the chemical dependence of the absorption coefficient of Cr(III) is less important in XANES than in optical absorption spectroscopy. The comparison of optical absorption and XANES spectra of glasses melted under different conditions provides an indirect assessment of the molar extinction coefficient of Cr(VI) in glasses.  相似文献   
993.
The best established proteolytic event of osteoclasts is bone matrix solubilization by the cysteine proteinase cathepsin K. Here, however, we draw the attention on osteoclastic activities depending on matrix metalloproteinases (MMPs). We discuss the observations supporting that MMPs contribute significantly to bone matrix solubilization in specific areas of the skeleton and in some developmental and pathological situations. Our discussion takes into account (1) the characteristics of the bone remodeling persisting in the absence of cathepsin K, (2) the ultrastructure of the resorption zone in response to inactivation of MMPs and of cathepsin K in different bone types, (3) bone resorption levels in MMP knockout mice compared to wild-type mice, (4) the identification of MMPs in osteoclasts and surrounding cells, and (5) the effect of different bone pathologies on the serum concentrations of specific collagen fragments believed to discriminate between cathepsin K and MMP cleavage. Next, we provide evidence that MMPs are very critical for osteoclast migration, thereby controlling also the cell-matrix interactions required for cell attachment/detachment. The evidence supporting this role is based on a model of osteoclast recruitment in primitive long bones, an assay of osteoclast invasion through collagen gel, and the effect of proteinase inhibitors/knockouts in these models. Furthermore, we mention observations indicating a role of MMPs in initiation of bone resorption. Finally, we emphasize the many distinct ways MMPs may alter focally the extracellular environment thereby regulating the osteoclast behavior. Although the understanding of MMPs in osteoclast biology is rapidly expanding, it is suspected that important roles remain to be discovered.  相似文献   
994.
995.
A three‐component probe harnesses the extraordinary properties of a solid‐state fluorophore for the detection of living cells exhibiting a particular peptidase activity. The off–on mode by which the probe operates, the bright fluorescence of the resulting precipitate, and the rapid response allow an exceptional signal‐to‐background ratio during microscopic imaging. A tertiary carbamate link between the spacer and phenolic fluorophore is at the heart of the probe's long‐term stability. The degree of chlorination of the probe determines its response time and thus its suitability for live‐cell analysis. Our probe also allows highly resolved localization of peptidase activity during gel analysis or on agar. In comparison, probes releasing soluble fluorophores demonstrate complete diffusion of the fluorescent signal. These results demonstrate the probe's potential for diverse biomedical applications, including high‐fidelity flow cytometry and sensitive colony assays.  相似文献   
996.
River basin metal pollution originates from heavy industries (plating, automobile) and from urban sources (Paris conurbation: 2740 km(2), 9.47 million inhabitants). The natural sources of metal have been found to be limited due to sedimentary nature of this catchment and to the very low river sediment transport (10 t km(-2) y(-1)). Several types of data have been collected to build the metal budget within the whole Seine River basin: field surveys, economical statistics and environmental models. Environmental contamination and related fluxes have been measured on atmospheric fallout, rural streams particles, and Seine River particles upstream and downstream of Paris and at river mouth. Metal pathways and budgets have been set up for (i) a typical cultivated area, (ii) a Paris combined sewer system, (iii) Paris conurbation and (iv) the whole catchment metal retention effect in floodplain and dredged material. Metal fluxes to the estuary have been decomposed into natural, urban domestic and other sources. The latter are within 1-2 orders of magnitude larger than waste water fluxes directly released into rivers according to an industrial census. These fluxes have been further compared to the annual use (1994-2003) of these metals. Metal excess fluxes exported by the river are now a marginal leak of metal inputs to the catchment (i.e. "raw" metals, metals in goods, atmospheric fallout), generally from 0.2 to 5 per thousand. However, due to the very limited dilution power in this basin, the contamination of particles is still relatively high. The Seine River basin is gradually storing metals, mostly in manufactured products used in construction, but also in various waste dumps, industrial soils, agricultural and flood plain soils.  相似文献   
997.
Although the effect of acoustic cues on speech segmentation has been extensively investigated, the role of higher order information (e.g., syntax) has received less attention. Here, the authors examined whether syntactic expectations based on subject-verb agreement have an effect on segmentation and whether they do so despite conflicting acoustic cues. Although participants detected target words faster in phrases containing adequate acoustic cues ("spins" in take spins and "pins" in takes pins), this acoustic effect was suppressed when the phrases were appended to a plural context (those women take spins/*takes pins [with the asterisk indicating a syntactically unacceptable parse]). The syntactically congruent target ("spins") was detected faster regardless of the acoustics. However, a singular context (that woman *take spins/takes pins) had no effect on segmentation, and the results resembled those of the neutral phrases. Subsequent experiments showed that the discrepancy was due to the relative time course of syntactic expectations and acoustics cues. Taken together, the data suggest that syntactic knowledge can facilitate segmentation but that its effect is substantially attenuated if conflicting acoustic cues are encountered before full realization of the syntactic constraint. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
998.
P2P文件共享网中病毒传播建模   总被引:1,自引:0,他引:1  
鉴于病毒在P2P文件共享网中的巨大危害性,对P2P文件共享网和P2P病毒的传播特点进行了深入的分析,并在此基础上提出了P2P病毒的传播模型。为了考查模型中各参数对病毒传播的影响,使用了专门的数字分析软件进行了大规模仿真实验。不同参数对病毒传播有着不同影响这一仿真实验结果表明,可以通过控制那些影响大的参数来抑制病毒传播。  相似文献   
999.
This paper describes KAZOO, a web application for sign language (SL) generation using a virtual signer. Firstly, it explains the motivation to this project, which is grounded on an approach designed solely from SL corpus analysis and modelling. Then, various projects conducted in the past few years on linguistic modelling and 3D animation are presented. The platform’s architecture integrates parts of this work and new pieces of software allowing control and linking of all these components. This is an ongoing project, though the current version offers the possibility to animate a virtual signer automatically and synthesize the contents using an abstract representation, the authors’ own linguistic model AZee, providing a means of validating this model.  相似文献   
1000.
The objective of this research is to evaluate the effect of providing online feedback, process, and process plus performance on visual search performance for a printed circuit board inspection task. A training aid was developed that provided process and process plus performance feedback and enabled a comparison between the two feedback strategies. Two search strategies—search by area and search by component—were adopted to complete the task, and their sensitivity to the type of feedback and search performance was evaluated. Providing process plus performance feedback helped in improving speed and accuracy, whereas area search strategy proved beneficial in improving search speed for both feedback strategies. Graphical feedback on the component location helped in locating more component defects than area defects. © 2003 Wiley Periodicals, Inc. Hum Factors Man 13: 115–136, 2003.  相似文献   
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