Effects of prognostic information on global ratings of psychotherapy outcome.

30 graduate students in clinical psychology (raters) viewed a videotape recording of an interview with a patient after having read 1 of 3 types of posttherapy information about the patient. One group of raters was presented information associated with a good prognosis, one group was presented information associated with a poor prognosis, and the last group received neutral information about the patient. Half of the members of each group were told that the interview was made at the termination of therapy, the other half were told that it was a 1-yr follow-up interview. All raters then completed scales regarding patient's level of adjustment, psychic distress, amount of change, and success of patient's therapy. Only ratings of pre- to posttherapy patient change varied as a function of prognostic information. Results suggest that although poor prognosis patients are perceived as exhibiting more change than good prognosis patients, only final level of functioning determines global judgments of psychotherapy outcome. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Dual source fourier transform polarization modulation spectroscopy: an improved method for the measurement of circular and linear dichroism

It is shown that the use of two sources in a four-port interferometer equipped with cube-corner mirrors leads to increased signal-to-noise ratios in Fourier transform (FT-IR) circular and linear dichroism spectra. The output beam to the sample is a superposition of two interferograms, one from each source, having opposite Fourier phases. These two interferograms cancel one another to the degree that the two sources are matched in intensity. If the radiation from each of the two sources is first polarized orthogonally with respect to the other and passed through a polarization modulator before reaching the sample, the resulting polarization-modulation interferograms are out of Fourier phase and out of polarization-modulation phase. As a result, the polarization-modulation interferograms, due to circular or linear dichroism in the sample, from the two sources combine positively rather than negatively. An improvement in signal-to-noise ratio of up to two (or a factor of four in scan-time reduction for the same signal-to-noise ratio) compared to single source operation can be realized, while at the same time, the potential for saturation of the detector signal is significantly reduced due to the reduction in magnitude of the combined ordinary infrared transmission interferogram. Absorption and circular dichroism spectra from a dual-source FT-IR spectrometer are presented and analyzed.     

Optimizing Transportation Problems with Multiple Objectives

Virtually all models developed for transportation problems have focused upon the optimization of a single objective criterion, namely the minimization of total transportation costs. They have generally neglected or often ignored the multiple conflicting objectives involved in the problem, the priority structure of these objectives, various environmental constraints, unique organizational values of the firm, and bureaucratic decision structures. However, in reality these are important factors which greatly influence the decision process of transportation problems. In this study the goal programming approach is utilized in order to allow for the optimization of multiple conflicting goals while permitting an explicit consideration of the existing decision environment.     

The role of rehabilitation psychologists in the treatment of disease and disability.

It is contended that rehabilitation psychologists have remained content to continue using the same techniques for the same types of problems that they used more than a decade ago. Because of a temerity of thought, rehabilitation psychologists have not extended their particular research and technological expertise into the more major areas of health care. Examples are presented in which such psychological techniques as conditioning and biofeedback were employed to treat successfully a variety of serious health problems. Rather than leave the major areas of investigation and treatment to others, as has traditionally been the case, rehabilitation psychologists are urged to utilize their skills in studying and treating the major physical problems of their patients. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Controlled modification and direct characterization of multimode-fiber refractive-index profiles

A combination of controlled annealing and characterization by scanning probe microscopy (SPM) is used to demonstrate that the refractive-index proffle of a commercially available silica-based optical fiber can be accurately reconfigured for use as an evanescent field sensor. The process relies on the controlled relocation of the silica glass dopants across the fiber cross section through heat treatment and the accurate measurement of the resulting dopant redistribution with SPM and differential etching techniques. The effect of variable annealing along a length of fiber is to produce a mode transformer to couple light from a laser source into the sensing region of the fiber.     

Resonance Raman spectroscopy of photolabile transition metal carbonyls: controlled photoalteration with continuous wave lasers to record spectra of reactants or transient species

A method has been developed that enables resonance Raman spectra of photolabile species in solution to be recorded under conditions where the level of photoalteration is controlled: a low level enables reactant spectra to be recorded, whereas a high level enables the spectra of short-lived transient species to be recorded in real time using continuous-wave (CW) lasers and standard Raman detection equipment. The design includes a sealed flow system, enabling air-sensitive species to be studied under an inert atmosphere. A simple theoretical model has been developed to aid the interpretation of experimental results, and its applicability is demonstrated. Controlled photoalteration and its theory are demonstrated with 413.1-nm excitation of carbonmonoxymyoglobin (MbCO), which generates deoxymyoglobin (deoxy-Mb) on photolysis, and for which the spectra of both species are well established. The methods have also been applied to two air-sensitive, photolabile transition metal carbonyls using 514.5-nm wavelength excitation: for Cp2Mo2(CO)6 (Cp = eta5-C5H5), increasing levels of photoalteration result only in a decrease in the parent band intensities, relative to the solvent bands; for Cp2Fe2(CO)4, increasing levels of photoalteration result in the appearance of additional bands that are assigned to the transient species CpFe(mu-CO)3FeCp, formed following the loss of a CO ligand.     

Atomic resolution of lithium ions in LiCoO2

LiCoO2 is the most common lithium storage material for lithium rechargeable batteries, used widely to power portable electronic devices such as laptop computers. Operation of lithium rechargeable batteries is dependent on reversible lithium insertion and extraction processes into and from the host materials of lithium storage. Ordering of lithium and vacancies has a profound effect on the physical properties of the host materials and the electrochemical performance of lithium batteries. However, probing lithium ions has been difficult when using traditional X-ray and neutron powder diffraction techniques due to lithium's relatively low scattering power when compared with those of oxygen and transition metals. In the work presented here, we have succeeded in simultaneously resolving columns of cobalt, oxygen and lithium atoms in layered LiCoO2 battery material, using experimental focal series of LiCoO2 images obtained at sub-?ngstrom resolution in a mid-voltage transmission electron microscope. Lithium atoms are the smallest and lightest metal atoms, and scatter electrons only very weakly. We believe our observations of lithium to be the first by electron microscopy, and that they show promise for direct visualization of the ordering of lithium and vacancies in transition metal oxides.     

Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans

Thymidine monophosphate kinase (TMPK) from Mycobacterium tuberculosis (TMPKmt) is an attractive target for the design of specific inhibitors. This fact is the result of its key role in the thymidine pathway and of unique structural features in the active site observed by X-ray crystallography, especially in comparison to its human counterpart (TMPKh). Different 5-modified thymidine derivatives, as well as purine and pyrimidine analogues or C-nucleosides were tested on TMPKmt and TMPKh, and the results were rationalized by docking studies. 5-Halogenated 2'-deoxyuridines are the best inhibitors of TMPKmt found and present the highest selectivity indexes in favor of TMPKmt.     

A New Sidelobe Correction Algorithm for Microwave Radiometers: Application to the Envisat Instrument

The antenna temperature measured by a microwave radiometer is converted in brightness temperature (TB) by removing the different contributions that do not come from the main lobe of the antenna. Among them, the Earth contribution in the sidelobes may be significant as for the Environmental Satellite mission due to the antenna position on the platform. In such a case, simple corrections commonly applied on previous altimetry missions are inadequate, and a more accurate correction should be determined. We propose in this paper a new method based on global seasonal tables of contamination. This allows application of an accurate sidelobe correction in space and time in the retrieved TB computation     

成功变革的关键战胜心中的"洞中人"

任何新事物都会遇到抵抗.事情总是这样.每个组织都有一种免疫系统,具备自动袭击任何变化的抗体.