温度梯度机理下激光参数对激光成形的影响

以纯铝板和低碳钢板为主要研究对象，对温度梯度机理下激光输入功率、扫描速度、离焦量以及扫描次数等参数与成形弯曲角之间的关系进行了试验研究，深入分析了温度梯度机理下影响成形的主要因素。     

Remanufacturability and Assessment Method

WITH the development of surface engineering andlaws on environment protect,lots of companies have toconsider reclaim of the used products.In practice,theyrealized if the products adopt design forremanufacturing,the benefit of remanufacturing wouldbe increased obviously'1'.Some researcher haveentered into remanufacturability field and built relativeevaluating methods'2'.Based on researching resultabout design for remanufacturing,some concepts,remanufacturability system and assessment method ar…     

工业项目的海绵城市建设标准与技术要点

工业用地是城市建设用地的主要类型之一,是海绵城市建设的重要区域。通过梳理工业项目硬化面积高、径流污染程度高等特征,针对性提出其海绵城市建设的实施路径、建设标准和技术应用等实施建议。工业项目的海绵城市设计应遵循因地制宜的原则,应合理布局绿地并建设海绵设施,通过精细化的标高设计进行径流组织设计;对于降雨径流污染严重的三类工业项目,其海绵措施应以雨水调蓄池(应急事故池)为主,严禁设置具有渗透功能的源头控制设施。对于三类工业项目,海绵城市所提出的年径流总量控制率的目标与事故池的环保要求基本一致,建议相关部门在制定(修订)的应急事故池设计标准时,其中的径流污染控制体积可与对应区域年径流总量控制率标准协同一致。     

国产羟丙基甲基纤维素在高聚合度聚氯乙烯生产中的应用

介绍了国产羟丙基甲基纤维素替代进口羟丙基甲基纤维素在高聚合度聚氯乙烯聚合中的应用,考察了两种羟丙基甲基纤维素对高聚合度聚氯乙烯树脂各项指标的影响.结果 表明,国产羟丙基甲基纤维素替代进口羟丙基甲基纤维素是可行的.     

Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis

Chronic wasting disease (CWD) is a prion disease found in both free-ranging and farmed cervids. Susceptibility of these animals to CWD is governed by various exogenous and endogenous factors. Past studies have demonstrated that polymorphisms within the prion protein (PrP) sequence itself affect an animal’s susceptibility to CWD. PrP polymorphisms can modulate CWD pathogenesis in two ways: the ability of the endogenous prion protein (PrP^C) to convert into infectious prions (PrP^Sc) or it can give rise to novel prion strains. In vivo studies in susceptible cervids, complemented by studies in transgenic mice expressing the corresponding cervid PrP sequence, show that each polymorphism has distinct effects on both PrP^C and PrP^Sc. It is not entirely clear how these polymorphisms are responsible for these effects, but in vitro studies suggest they play a role in modifying PrP epitopes crucial for PrP^C to PrP^Sc conversion and determining PrP^C stability. PrP polymorphisms are unique to one or two cervid species and most confer a certain degree of reduced susceptibility to CWD. However, to date, there are no reports of polymorphic cervid PrP alleles providing absolute resistance to CWD. Studies on polymorphisms have focused on those found in CWD-endemic areas, with the hope that understanding the role of an animal’s genetics in CWD can help to predict, contain, or prevent transmission of CWD.     

粗糙集理论及其在图像处理中的应用*

首先描述了粗糙集理论的基本概念,包括粗糙集知识表示方法和粗糙集约简理论;叙述了粗糙集理论及其与其他非线性理论相结合在图像处理中的应用情况;最后指出了粗糙集理论应用于图像处理的基本思路,并指出将粗糙集理论与其他非线性理论相结合应用于图像处理,将会产生更加有效的结果.     

硫化胶中炭黑燃烧特性的研究

研究硫化胶中炭黑燃烧特性与对应炭黑原材料特性的关系,利用两者间的关系分析不同硫化胶中的炭黑品种,评价炭黑分散性。结果表明:硫化胶中炭黑燃烧特征温度与对应炭黑的压缩吸油值和氮吸附表面积均呈显著线性关系,相关因数分别为0.806 9和0.954 1;根据炭黑燃烧特征温度及线性回归方程推导出硫化胶中炭黑的压缩吸油值和氮吸附表面积,可以判定硫化胶中的炭黑品种;硫化胶中炭黑燃烧特征温度低,在一定程度上可以表明炭黑分散性良好。     

光伏发电接入对配电网低压台区线损的影响

随着可再生能源的不断开发,越来越多的光伏发电接入配电网,而光伏发电的不稳定性会对配电网的稳定造成影响。为此,针对光伏发电对配电网低压台区线损的影响,建立了电源接入模型并进行了仿真计算。     

脉冲作用下Tesla变压器绕组形变故障机理

Tesla变压器在高功率脉冲电源中占有重要地位,其次级绕组是机械故障损坏的主要部位.为了研究次级绕组充电过程中所受动态电磁力以及绕组机械故障机理,建立了有限元模型与集总电路相结合的绕组受力仿真模型.先使用COMSOL有限元分析软件提取Tesla变压器的分布参数,构建求解集总参数电路得到次级线圈的电位电流分布,然后将电流分布赋给有限元模型中的次级线圈作为磁场场源,计算磁场以及电磁力分布.仿真结果验证了平行于锥形线圈母线上的电磁力分量是引起绕组线圈错位的主要原因,且错位力的分布集中在两端,垂直于线圈母线上的压紧力有抵抗绕组变形的能力,在同样卷绕力下大径端的压紧力最小,是整个绕组受力的薄弱点,与实际统计结果大径端处故障频率高一致.在Tesla变压器的设计中应着重考虑加强次级绕组大径端处的机械强度.     

Molecular Dynamics Simulations Based on 1-Phenyl-4-Benzoyl-1-Hydro-Triazole ERRα Inverse Agonists

Estrogen-related receptor α (ERRα), which is overexpressed in a variety of cancers has been considered as an effective target for anticancer therapy. ERRα inverse agonists have been proven to effectively inhibit the migration and invasion of cancer cells. As few crystalline complexes have been reported, molecular dynamics (MD) simulations were carried out in this study to deepen the understanding of the interaction mechanism between inverse agonists and ERRα. The binding free energy was analyzed by the MM-GBSA method. The results show that the total binding free energy was positively correlated with the biological activity of an inverse agonist. The interaction of the inverse agonist with the hydrophobic interlayer composed of Phe328 and Phe495 had an important impact on the biological activity of inverse agonists, which was confirmed by the decomposition of energy on residues. As Glu331 flipped and formed a hydrogen bond with Arg372 in the MD simulation process, the formation of hydrogen bond interaction with Glu331 was not a necessary condition for the compound to act as an inverse agonist. These rules provide guidance for the design of new inverse agonists.