Metabolic P Systems： A Discrete Model for Biological Dynamics

A recent methodology to model biochem- ical systems is here presented. It is based on a concep- tual framework rooted in membrane computing and de- veloped with concepts typical of discrete dynamical sys- tems. According to our approach, from data observed at suitable macroscopic temporal scales, one can deduce, by means of algebraic and algorithmic procedures, a dis- crete model （called Metabolic P system） which accounts for the experimental data, and opens the possibility to under- stand the systemic logic of the investigated phenomenon. The procedures of such a method have been implemented within a computational platform, a Java software called MetaPlab, processing data and simulating behaviors of metabolic models. In the paper, we briefly describe the theory underlying the modeling of biochemical systems by Metabolic P systems, along with its development stages and the related extensive literature.     

Performance evaluation of an IEEE 802.11g mesh network with multiradio nodes

Wireless mesh networks are usually formed by self‐organized nodes and characterized by high reliability and modularity, low‐cost deployment, and easiness of reconfigurability. In order to improve wireless mesh network performance, several approaches have been recently proposed. Among them, one promising solution seems to be the multiradio interface approach where nodes forming the mesh network are equipped with more than one radio interface. The aim of this paper is to provide an IEEE 802.11 distributed coordination function analytical model to study the behavior of single‐hop multi‐interface mesh networks in which nodes use a uniform random interface selection strategy to identify the radio interface to be used. The accuracy of the proposed analytical approach is validated by comparing analytical predictions with simulation results under actual conditions. Copyright © 2011 John Wiley & Sons, Ltd.     

用于电源测试的精确压控电流阱

为了检测潜在的电源缺陷,必须进行动态和静态测试。这里的简单电流阱可测试低到中功率电源和恒压源。在该应用中,在输入电压范围为0V～5V,电源电压最高为20V时,电流阱可吸收0A～1.5A的电流。该电路的基本部件为一个精密运放IC1,采用Texas Instruments的OPA277。该器件特点为：最大输入偏置电压仅为100μV,最大输入偏置电流为4nA,在-40℃-＋85℃温度范围内温漂较低（图1）。运放IC将其正输入电压与检测电阻RSENSE上的电压进行比较。     

State‐of‐the‐Art Neutral Tint Multichromophoric Polymers for High‐Contrast See‐Through Electrochromic Devices

Two new multichromophoric electrochromic polymers featuring a conjugated EDOT/ProDOT copolymer backbone (PXDOT) and a reversible Weitz‐type redox active small molecule electrochrome (WTE) tethered to the conjugated chain are reported here. The careful design of the WTEs provides a highly reversible redox behavior with a colorless red switching that complements the colorless blue switching of the conjugated backbone. Subtractive color mixing successfully provides high performing solution processable polymeric layers with colorless neutral tint switchable limiting states for application in see‐through electrochromic devices. Design, synthesis, comprehensive chemical and spectroelectrochemical characterization as well as the preparation of a proof‐of‐concept device are discussed.     

Completely automated multiresolution edge snapper--a new technique for an accurate carotid ultrasound IMT measurement: clinical validation and benchmarking on a multi-institutional database

The aim of this paper is to describe a novel and completely automated technique for carotid artery (CA) recognition, far (distal) wall segmentation, and intima-media thickness (IMT) measurement, which is a strong clinical tool for risk assessment for cardiovascular diseases. The architecture of completely automated multiresolution edge snapper (CAMES) consists of the following two stages: 1) automated CA recognition based on a combination of scale-space and statistical classification in a multiresolution framework and 2) automated segmentation of lumen-intima (LI) and media-adventitia (MA) interfaces for the far (distal) wall and IMT measurement. Our database of 365 B-mode longitudinal carotid images is taken from four different institutions covering different ethnic backgrounds. The ground-truth (GT) database was the average manual segmentation from three clinical experts. The mean distance ± standard deviation of CAMES with respect to GT profiles for LI and MA interfaces were 0.081 ± 0.099 and 0.082 ± 0.197 mm, respectively. The IMT measurement error between CAMES and GT was 0.078 ± 0.112 mm. CAMES was benchmarked against a previously developed automated technique based on an integrated approach using feature-based extraction and classifier (CALEX). Although CAMES underestimated the IMT value, it had shown a strong improvement in segmentation errors against CALEX for LI and MA interfaces by 8% and 42%, respectively. The overall IMT measurement bias for CAMES improved by 36% against CALEX. Finally, this paper demonstrated that the figure-of-merit of CAMES was 95.8% compared with 87.4% for CALEX. The combination of multiresolution CA recognition and far-wall segmentation led to an automated, low-complexity, real-time, and accurate technique for carotid IMT measurement. Validation on a multiethnic/multi-institutional data set demonstrated the robustness of the technique, which can constitute a clinically valid IMT measurement for assistance in atherosclerosis disease management.     

Using SPDY to improve Web 2.0 over satellite links

During the last decade, the Web has grown in terms of complexity, while the evolution of the HTTP (Hypertext Transfer Protocol) has not experienced the same trend. Even if HTTP 1.1 adds improvements like persistent connections and request pipelining, they are not decisive, especially in modern mixed wireless/wired networks, often including satellites. The latter play a key role for accessing the Internet everywhere, and they are one of the preferred methods to provide connectivity in rural areas or for disaster relief operations. However, they suffer of high‐latency and packet losses, which degrade the browsing experience. Consequently, the investigation of protocols mitigating the limitations of HTTP, also in challenging scenarios, is crucial both for the industry and the academia. In this perspective, SPDY, which is a protocol optimized for the access to Web 2.0 contents over fixed and mobile devices, could be suitable also for satellite links. Therefore, this paper evaluates its performance when used both in real and emulated satellite scenarios. Results indicate the effectiveness of SPDY if compared with HTTP, but at the price of a more fragile behavior when in the presence of errors. Besides, SPDY can also reduce the transport overhead experienced by middleboxes typically deployed by service providers using satellite links. Copyright © 2016 John Wiley & Sons, Ltd.     

Estimation of two-dimensional affine transformations through polar curve matching and its application to image mosaicking and remote-sensing data registration.

This paper presents a new and effective method for estimating two-dimensional affine transformations and its application to image registration. The method is based on matching polar curves obtained from the radial projections of the image energies, defined as the squared magnitudes of their Fourier transforms. Such matching is formulated as a simple minimization problem whose optimal solution is found with the Levenberg-Marquardt algorithm. The analysis of affine transformations in the frequency domain exploits the well-known property whereby the translational displacement in this domain can be factored out and separately estimated through phase correlation after the four remaining degrees of freedom of the affine warping have been determined. Another important contribution of this paper, emphasized through one example of image mosaicking and one example of remote sensing image registration, consists in showing that affine motion can be accurately estimated by applying our algorithm to the shapes of macrofeatures extracted from the images to register. The excellent performance of the algorithm is also shown through a synthetic example of motion estimation and its comparison with another standard registration technique.     

Recovery Time and Fault Tolerance Improvement for Circuits mapped on SRAM-based FPGAs

The rapid adoption of FPGA-based systems in space and avionics demands dependability rules from the design to the layout phases to protect against radiation effects. Triple Modular Redundancy is a widely used fault tolerance methodology to protect circuits against radiation-induced Single Event Upsets implemented on SRAM-based FPGAs. The accumulation of SEUs in the configuration memory can cause the TMR replicas to fail, requiring a periodic write-back of the configuration bit-stream. The associated system downtime due to scrubbing and the probability of simultaneous failures of two TMR domains are increasing with growing device densities. We propose a methodology to reduce the recovery time of TMR circuits with increased resilience to Cross-Domain Errors. Our methodology consists of an automated tool-flow for fine-grain error detection, error flags convergence and non-overlapping domain placement. The fine-grain error detection logic identifies the faulty domain using gate-level functions while the error flag convergence logic reduces the overwhelming number of flag signals. The non-overlapping placement enables selective domain reconfiguration and greatly reduces the number of Cross-Domain Errors. Our results demonstrate an evident reduction of the recovery time due to fast error detection time and selective partial reconfiguration of faulty domains. Moreover, the methodology drastically reduces Cross-Domain Errors in Look-Up Tables and routing resources. The improvements in recovery time and fault tolerance are achieved at an area overhead of a single LUT per majority voter in TMR circuits.     

Hybrid Photonic Nanostructures by In Vivo Incorporation of an Organic Fluorophore into Diatom Algae

Biotechnological processes harnessing living organisms' metabolism are low‐cost routes to nanostructured materials for applications in photonics, electronics, and nanomedicine. In the pursuit of photonic biohybrids, diatoms microalgae are attractive given the properties of the porous micro‐to‐nanoscale structures of the biosilica shells (frustules) they produce. The investigations have focused on in vivo incorporation of tailored molecular fluorophores into the frustules of Thalassiosira weissflogii diatoms, using a procedure that paves the way for easy biotechnological production of photonic nanostructures. The procedure ensures uniform staining of shells in the treated culture and permits the resulting biohybrid photonic nanostructures to be isolated with no damage to the dye and periodic biosilica network. Significantly, this approach ensures that light emission from the dye embedded in the isolated biohybrid silica is modulated by the silica's nanostructure, whereas no modulation of photoluminescence is observed upon grafting the fluorophore onto frustules by an in vitro approach based on surface chemistry. These results pave the way to the possibility of easy production of photonic nanostructures with tunable properties by simple feeding the diatoms algae with tailored photoactive molecules.