烟碱向降烟碱转化对烟叶麦斯明和TSNA含量的影响

以白肋烟TN90为材料,研究了非转化株、低转化株及高转化株烟叶样品的烟碱转化程度及降烟碱含量与烟叶麦斯明和烟草特有亚硝胺(TSNA)含量的关系。结果表明,随着烟株烟碱转化能力的提高和烟叶降烟碱含量的增加,叶片和主脉的麦斯明含量呈线性增加。当烟碱转化率超过20％时,麦斯明含量超过了假木贼碱的含量。在4种主要的TSNA中,具有不同烟碱转化能力的样品间4-(甲基亚硝胺基)-1-(3-吡啶基)-1-丁酮(NNK)、N-亚硝基新烟草碱(NAT)和N-亚硝基假木贼碱(NAB)含量没有显著差异,N-亚硝基降烟碱(NNN)含量则随着烟碱转化能力的提高和降烟碱含量的增加而大幅度升高,尤其在主脉中表现更为明显。NNN占总TSNA的比例随烟碱转化程度的提高而增加,在高转化烟株中可高达90％,其它3种TSNA占总TSNA的比例相应降低。叶片中NAT含量和比例一般高于NNK,而在主脉中NNK含量高于NAT。     

在受限和通风防火分区内对燃烧速率特性的试验研究

在核安全研究框架内对在受限和通风防火分区内油池火燃烧速率进行了试验研究。在实体火灾试验基础上，此研究为在受限和通风火灾场景下的燃烧速率机理提供了新的信息。描述了在自由条件和空气受限条件下所进行的试验，对试验装置、仪器以及火源进行了详细叙述。在相同场景（0．4m^2TPH油池火）下，对自由条件和空气受限条件的试验情况下的燃烧速率进行了对比。在空气受限情况下，燃烧速率与时间的变化曲线显示出三个不同阶段：自由条件和受限燃烧速率相同；不稳定阶段，空气受限条件下燃烧速率高于自由条件下的燃烧速率;稳定阶段。从图像分析看，不稳定阶段显示，动荡和间歇火焰大大提高了燃烧速率。介绍了通风速率和油池面积对此现象的影响。试验结果为理解有限区域内燃烧速率提供了新的试验信息。     

Experimental validation of models for predicting optimal surface quality sterilization temperatures

An experimental procedure was developed to validate experimentally the theoretical optimal process temperatures giving the maximum quality at the surface of conduction heating products for specified levels of sterility. the method involved filling a can with a 10% bentonite solution, placing glass capillaries containing a food quality indicator at the surface, and processing it at different temperatures for the necessary time in order to attain a specified sterility value at the least-lethality point. the acid catalysed sucrose hydrolysis reaction was used as a chemical time-temperature-integrator for a quality index of heat sterilized products. At a pH of 3.8, the kinetic parameters D_121.15°C ard z values of this reaction, were 214min and 31°C, respectively. Final surface retentions of sucrose compared well with theoretically predicted values from simulation modelling. Optimal temperatures calculated using either numerical computer optimization or generalized regression equations were in the range of experimentally determined optimal conditions.     

An Updated Out-of-Core Equation Solver

An assembly method is presented to be used with out-of-core blocked skyline equation solvers. The equation assembly forms the blocked components of the simultaneous equations directly, while reducing input/output (I/O)to a minimum. The assembly is intended to be inserted into finite-element codes and is ideal for microcomputer use. The memory used for both assembly and solution.     

Analysis of tumor-draining vein secretome: A direct access to tumor-derived extracellular vesicles in surgical lung cancer patients

Tumor-secreted extracellular vesicles (EVs) participate in the metastasis process through different mechanisms, including the preparation of the pre-metastatic niche to grant circulating tumor cells (CTCs) implantation and growth. The study of the metastasis process through the analysis of CTCs and tumor-derived EVs is difficult because of the dilution grade of these elements in peripheral blood. In early-stage lung cancer patients, the tumor-secreted products are even more diluted. An attractive strategy in surgical lung cancer patients is to purify them from a pulmonary tumor-draining vein where they are enriched. The information obtained from the analysis of EVs and CTCs purified from this source could give more accurate information about tumor biology and could be an important source of biomarkers to identify patients at high risk of relapse after curative surgery.     

Protective stocks in multi-stage production systems

Uncertainty in MRP systems does exist in several forms, variability in demand from period to period, uncertainty in the supply from stage to stage due to the variability in the yields from each production batch, and uncertainty in the lead times. The goals of the paper are to develop theoretical models for determining optimal decisions in this uncertain environment, to develop a computationally tractable heuristic and to examine how safety stock and safety time can arise. Finally, our methodology is compared with MRP practice.     

EXPERIMENTAL STUDY OF A COMPLEX CATALYTIC REACTION NETWORK IN A TRICKLE-BED REACTOR

In the present report a relatively complex reaction system including several side reactions to the desired main reaction has been studied in a trickle-bed reactor. In addition the experimental part—which showed very good reproducibility of the results—an attempt to a reasonable modelling of the reactor was tried. The starting point was the differential equation system describing the kinetics of the reactions as well as the corresponding kinetic parameters, which had been established earlier in a slurry-reactor. It was possible to demonstrate that the behaviour of a trickle-bed reactor can be simulated by a relatively simple approach containing the basic kinetic equations, the wetting efficiency of the catalyst particles and a one-dimensional, pseudohomogeneous reactor model, the cell model. The so calculated concentration curves of the different reactants and products fitted the experimental values very closely. For those reasons, and especially for the reasonable effort needed for very satisfactory modeling, the results and proceeding steps outlined here might be of particular interest for further applications of trickle-bed reactors.