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991.
992.
隐马尔科夫模型(Hidden Markov Model)在诸多领域都有广泛应用.本文从不同角度对现有的HMM进行改进并应用于金融预测.首先,我们采取固定K-means方法的初始点,使得K-means的聚类结果更加稳定,由此为Baum-Welch算法确定更好的初始迭代值.其次,为更进一步提升预测效果,与已有方法不同,我们将由BaumWelch算法所得到的模型参数值作为Vertibi算法的输入来确定隐状态的最优取值序列,由此重新划分观测向量,进而得到各个隐状态对应的观测向量的集合;基于Vertibi算法的输出结果,我们重新计算不同类观测向量的均值与方差,将新的均值向量和协方差矩阵作为Baum-Welch算法初始迭代值,最终确定HMM最优的模型参数.最后,代替现有方法仅在历史区间中简单寻求相似走势的做法,我们不仅导出了预测值发生的多步条件概率的精细表达式,而且通过极大化该条件概率的值来得到更佳的预测值.基于中国证券市场具体数据的实证结果表明了本文所提出改进HMM的优越性. 相似文献
993.
Enhanced and Differential Capture of Circulating Tumor Cells from Lung Cancer Patients by Microfluidic Assays Using Aptamer Cocktail 下载免费PDF全文
Libo Zhao Chuanhao Tang Li Xu Zhen Zhang Xiaoyan Li Haixu Hu Si Cheng Wei Zhou Mengfei Huang Anna Fong Bing Liu Hsian‐Rong Tseng Hongjun Gao Yi Liu Xiaohong Fang 《Small (Weinheim an der Bergstrasse, Germany)》2016,12(8):1072-1081
Collecting circulating tumor cells (CTCs) shed from solid tumor through a minimally invasive approach provides an opportunity to solve a long‐standing oncology problem, the real‐time monitoring of tumor state and analysis of tumor heterogeneity. However, efficient capture and detection of CTCs with diverse phenotypes is still challenging. In this work, a microfluidic assay is developed using the rationally‐designed aptamer cocktails with synergistic effect. Enhanced and differential capture of CTCs for nonsmall cell lung cancer (NSCLC) patients is achieved. It is also demonstrated that the overall consideration of CTC counts obtained by multiple aptamer combinations can provide more comprehensive information in treatment monitoring. 相似文献
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995.
Monolithic and Flexible ZnS/SnO2 Ultraviolet Photodetectors with Lateral Graphene Electrodes 下载免费PDF全文
Cheng Zhang Yunchao Xie Heng Deng Travis Tumlin Chi Zhang Jheng‐Wun Su Ping Yu Jian Lin 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(18)
A continuing trend of miniaturized and flexible electronics/optoelectronic calls for novel device architectures made by compatible fabrication techniques. However, traditional layer‐to‐layer structures cannot satisfy such a need. Herein, a novel monolithic optoelectronic device fabricated by a mask‐free laser direct writing method is demonstrated in which in situ laser induced graphene‐like materials are employed as lateral electrodes for flexible ZnS/SnO2 ultraviolet photodetectors. Specifically, a ZnS/SnO2 thin film comprised of heterogeneous ZnS/SnO2 nanoparticles is first coated on polyimide (PI) sheets by a solution process. Then, CO2 laser irradiation ablates designed areas of the ZnS/SnO2 thin film and converts the underneath PI into highly conductive graphene as the lateral electrodes for the monolithic photodetectors. This in situ growth method provides good interfaces between the graphene electrodes and the semiconducting ZnS/SnO2 resulting in high optoelectronic performance. The lateral electrode structure reduces total thickness of the devices, thus minimizing the strain and improving flexibility of the photodetectors. The demonstrated lithography‐free monolithic fabrication is a simple and cost‐effective method, showing a great potential for developement into roll‐to‐roll manufacturing of flexible electronics. 相似文献
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Prof. Dr.‐Ing. Falk Jaeger 《Mauerwerk》2019,23(1):50-54
Brick masonry is not only a question of building physics, building construction and durability, i.e. sustainability, but has much to do with aesthetics and making sense, which may have been forgotten in modern architecture with its absolute lack of décor. Masonry as an art form has been scarce since the era of brick expressionism. Recently, there have been some exceptions – and thoroughly welcome. The ”Fjordenhus“ in Vejle, Denmark, is an astonishing example. 相似文献
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Z.X. Li X. Zhuo L. Vu‐Quoc B.A. Izzuddin H.Y. Wei 《International journal for numerical methods in engineering》2013,95(3):181-211
A four‐node corotational quadrilateral elastoplastic shell element is presented. The local coordinate system of the element is defined by the two bisectors of the diagonal vectors generated from the four corner nodes and their cross product. This local coordinate system rotates rigidly with the element but does not deform with the element. As a result, the element rigid‐body rotations are excluded in calculating the local nodal variables from the global nodal variables. The two smallest components of each nodal orientation vector are defined as rotational variables, leading to the desired additive property for all nodal variables in a nonlinear incremental solution procedure. Different from other existing corotational finite‐element formulations, the resulting element tangent stiffness matrix is symmetric owing to the commutativity of the local nodal variables in calculating the second derivative of strains with respect to these variables. For elastoplastic analyses, the Maxwell–Huber–Hencky–von Mises yield criterion is employed, together with the backward‐Euler return‐mapping method, for the evaluation of the elastoplastic stress state; the consistent tangent modulus matrix is derived. To eliminate locking problems, we use the assumed strain method. Several elastic patch tests and elastoplastic plate/shell problems undergoing large deformation are solved to demonstrate the computational efficiency and accuracy of the proposed formulation. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献