全文获取类型
收费全文 | 380篇 |
免费 | 40篇 |
专业分类
电工技术 | 1篇 |
综合类 | 1篇 |
化学工业 | 111篇 |
金属工艺 | 7篇 |
机械仪表 | 9篇 |
建筑科学 | 14篇 |
能源动力 | 9篇 |
轻工业 | 106篇 |
水利工程 | 3篇 |
石油天然气 | 3篇 |
无线电 | 13篇 |
一般工业技术 | 42篇 |
冶金工业 | 21篇 |
原子能技术 | 1篇 |
自动化技术 | 79篇 |
出版年
2023年 | 3篇 |
2022年 | 18篇 |
2021年 | 30篇 |
2020年 | 20篇 |
2019年 | 15篇 |
2018年 | 14篇 |
2017年 | 17篇 |
2016年 | 24篇 |
2015年 | 14篇 |
2014年 | 20篇 |
2013年 | 28篇 |
2012年 | 32篇 |
2011年 | 33篇 |
2010年 | 21篇 |
2009年 | 20篇 |
2008年 | 19篇 |
2007年 | 16篇 |
2006年 | 16篇 |
2005年 | 8篇 |
2004年 | 4篇 |
2003年 | 7篇 |
2002年 | 4篇 |
2001年 | 5篇 |
1999年 | 2篇 |
1998年 | 10篇 |
1997年 | 5篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1980年 | 2篇 |
排序方式: 共有420条查询结果,搜索用时 708 毫秒
221.
Dieter Leupold Lutz Pfeifer Maja Hofmann Andrea Forschner Gerd Wessler Holger Haenssle 《International journal of molecular sciences》2021,22(10)
The melanin fluorescence emitted by pigment cells of the human skin has been a central research topic for decades, because melanin, on the one hand, protects against (solar) radiation in the near-UV range, whereas on the other hand, melanocytes are the starting point for the malignant transformation into melanoma. Until recently, however, melanin fluorescence was not accessible in the context of conventional spectroscopy, because it is ultraweak and is overshadowed by the more intense so-called autofluorescence of endogenous fluorophores. The advent of a new method of laser spectroscopy has made this melanin fluorescence measurable in vivo. A stepwise two-photon absorption with 800 nm photons is used, which more selectively excites melanin (dermatofluoroscopy). Our review summarizes the experimental results on melanin fluorescence of the four types of cutaneous pigment cells from healthy and malignant tissues. Outstanding is the finding that different types of melanocytes (i.e., melanocytes of common nevi, versus dysplastic nevi or versus melanoma cells) show characteristically different fluorescence spectra. The possibilities of using this melanin fluorescence for melanoma diagnosis are shown. Moreover, the uniform fluorescence spectra emitted by different melanoma subtypes are essential. Conclusions are drawn about the molecular processes in the melanosomes that determine fluorescence. Finally, experimental suggestions for further investigations are given. 相似文献
222.
Daniela Jakšić Miranda Sertić Domagoj Kifer Sandor Kocsubè Ana Mornar Turk Biljana Nigović Bojan Šarkanj Rudolf Krska Michael Sulyok Maja Šegvić Klarić 《Indoor air》2021,31(3):730-744
In winter and summer of 2016 and 2017, airborne fungi and house dust were collected in indoors of the village Gunja, which had been flooded, and the control village Gornji Stupnik (Croatia) in order to explore variations of fungal indoor levels, particularly Aspergilli section Nidulantes series Versicolores, as well as fungal metabolites in dust. Levels of airborne Aspergilli (Versicolores) were three times as high in winter and summer in Gunja than in the control village, while dustborne isolates were equally present in both locations. Sequencing of the calmodulin gene region revealed that among Aspergilli (Versicolores), A. jensenii and A. creber were dominant and together with A. puulaauensis, A. tennesseensis and A. venenatus produced sterigmatocystin and 5-methoxysterigmatocystin (HPLC coupled with mass spectrometry); A. amoenus, A. fructus, A. griseoaurantiacus, A. pepii, and A. protuberus produced sterigmatocystin but not 5-methoxysterigmatocystin; A. sydowii did not produce any of these toxins. A total of 75 metabolites related to Penicillium (29), Aspergillus (22), Fusarium (10), Alternaria (5), Stachybotrys (2), and other fungi (7) were detected in dust by liquid chromatography-tandem mass spectrometry. The majority of metabolites including sterigmatocystin and 5-methoxysterigmatocystin exhibited a higher prevalence in winter in Gunja. 相似文献
223.
Maja Kuzmanović Laurens Delva Ludwig Cardon Kim Ragaert 《Advanced materials (Deerfield Beach, Fla.)》2020,32(52):2003938
The relationship between processing, morphology, and properties of polymeric materials has been the subject of numerous studies of academic and industrial research. Finding an answer to this question might result in guidelines on how to design polymeric materials. Microfibrillar composites (MFCs) are an interesting class of polymer–polymer composites. The advantage of the MFC concept lies in developing in situ microfibrils by which a perfect homogeneous distribution of the reinforcement in the matrix can be achieved. Their potentially excellent mechanical properties are strongly dependent on the aspect ratio of the fibrils, which is developed through a three-stage production process: melt blending, fibrillation, and isotropization. During melt blending, the polymers undergo different morphological changes, such as a breakup and coalescence of the droplets, which play a crucial role in defining the microstructure. During processing, various parameters may affect the morphology of the MFCs, which must be taken into account. Besides the processing parameters, the microstructure of the composite is dependent on the composition ratio of the blend and viscosity of the components, as well as the dispersion and distribution of the microfibrils. The objective here is to outline this importance and bring together an overview of the processing–structure–property relationship for MFCs. 相似文献
224.
Tran Linh Kossaifi Jean Panagakis Yannis Pantic Maja 《International Journal of Computer Vision》2019,127(6-7):824-844
International Journal of Computer Vision - Deep generative models have significantly advanced image generation, enabling generation of visually pleasing images with realistic texture. Apart from... 相似文献
225.
226.
227.
Some of the most compelling characters are morally ambiguous, but little research has examined these characters. This study (N = 313) empirically tests the effects of good, bad, and morally ambiguous characters (MACs) on audience responses. Findings of an experiment reveal that different character types are appealing for different reasons. Specifically, good characters are enjoyed because they are well liked; bad characters are liked the least, but they are equally as transporting, suspenseful, and thus cognitively engaging as other characters. MACs, on the other hand, are liked less than good characters, but they are nevertheless equally as transporting, suspenseful, cognitively engaging, and thereby enjoyable as good characters. The implications of these findings on various media effects theories are discussed. 相似文献
228.
Scientometrics - This study aims to assess the role of authored and edited books in scholarly communication through citation analysis. It focuses on social science journal articles written by... 相似文献
229.
Rossana Paganoni Andr Lechel Maja Vujic Spasic 《International journal of molecular sciences》2021,22(8)
Cancer incidence and mortality are rapidly growing, with liver cancer being the sixth most diagnosed cancer worldwide and the third leading cause of cancer death in 2020. A number of risk factors have been identified that trigger the progression to hepatocellular carcinoma. In this review, we focus on iron as a potential risk factor for liver carcinogenesis. Molecules involved in the regulation of iron metabolism are often upregulated in cancer cells, in order to provide a supply of this essential trace element for all stages of tumor development, survival, proliferation, and metastasis. Thus, cellular and systemic iron levels must be tightly regulated to prevent or delay liver cancer progression. Disorders associated with dysregulated iron metabolism are characterized with increased susceptibility to hepatocellular carcinoma. This review discusses the association of iron with metabolic disorders such as hereditary hemochromatosis, non-alcoholic fatty liver disease, obesity, and type 2 diabetes, in the background of hepatocellular carcinoma. 相似文献
230.
Omid Sascha Yousefi Matias Ruggieri Vincent Idstein Kai Uwe von Prillwitz Laurenz A. Herr Julia Chalupsky Maja Khn Wilfried Weber Jens Timmer Wolfgang W. A. Schamel 《International journal of molecular sciences》2021,22(9)
Activation of T cells by agonistic peptide-MHC can be inhibited by antagonistic ones. However, the exact mechanism remains elusive. We used Jurkat cells expressing two different TCRs and tested whether stimulation of the endogenous TCR by agonistic anti-Vβ8 antibodies can be modulated by ligand-binding to the second, optogenetic TCR. The latter TCR uses phytochrome B tetramers (PhyBt) as ligand, the binding half-life of which can be altered by light. We show that this half-life determined whether the PhyBt acted as a second agonist (long half-life), an antagonist (short half-life) or did not have any influence (very short half-life) on calcium influx. A mathematical model of this cross-antagonism shows that a mechanism based on an inhibitory signal generated by early recruitment of a phosphatase and an activating signal by later recruitment of a kinase explains the data. 相似文献